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O&G PPQs Flashcards

1
Q

Which strains of HPV does gardasil protect against?

A

6, 11,16,18

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2
Q
  1. Gardasil: which HPV serotype from the list does it protect against? HIV, HSV1, HSV2, HPV11, HPV29?
A

HPV11

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3
Q

UTI in first trimester of pregnancy. What would be the safest and most effective treatment? Trimethoprim, Ciprofloxacin, Doxycycline, Cefalexin, Meropenem

A

Cefalexin

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4
Q
  1. Amenorrhoea for 4 months – what is the best initial investigation?
A

Beta HCG

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5
Q

Girl with cystic ovaries on US and irregular menstruation. What other symptom would be the best indicator of her having polycystic ovaries? Dysmenorrhoea, Hirsutism, Obesity, Acne.

A

Hirsutism

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6
Q

Woman with PCOS. Which medication to increase fertility should be given first?

A

Clomiphene

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7
Q

Man with azoospermia. What would be the most likely cause?

A

Variocele

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8
Q
  1. Post-menopausal woman with a PV bleed. What ix should you do?
A

Outpatient USS with endometrial biopsy

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9
Q
  1. Asymptomatic woman, nulliparous, found to have a 5.4cm unilocular ovarian cyst on US, no fhx. Mgmt/Ix? USS guided cyst aspiration, laparoscopic removal of cyst, discharge and safety-net, rearrange USS in 3 months and Ca-125 follow-up
A

Rearrange USS in 3 months and Ca-125 follow-up?

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10
Q

A woman presents 8 weeks after normal vaginal delivery and second degree tear, still bleeding and mild lower pelvic pain. Diagnosis? Normal menstruation, PID, endometritis, lochia

A

Endometritis

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11
Q
  1. What is a 21 week USS useful for? Nuchal thickness for Down’s, congenital heart disease identification, predicting position of placenta at term
A

Congenital heart disease identification (anomaly scan)

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12
Q

What causes increased urinary volume and frequency in the first trimester? Increased GFR, pressure of uterus on bladder, glycosuria

A

Increased GFR?

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13
Q

Effect of taking Paroxetine during pregnancy on baby?

A

In first trimester: small risk of congenital heart defects. In third trimester: risk of persistent pulmonary hypertension of the newborn

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14
Q
  1. Woman with Nexplanon. Most likely reason for wanting to change contraceptive? Weight gain, acne, mood swings, irregular bleeding
A

Irregular bleeding

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15
Q
  1. 14 year old girl wants TOP, can’t/will not inform parents. What do you do?
A

Assess whether she is Gillick competent

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16
Q
  1. Pregnant lady being domestically abused by husband and scared to go home. What do you do in GP? Send her home and ask her to come back with husband, give her a leaflet about domestic abuse, call and arrange emergency accommodation
A

call and arrange emergency accommodation

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17
Q
  1. Woman has pain before periods and has been subfertile, cyst found on ovary with a ground glass appearance on USS
A

Endometrioma

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18
Q
  1. 70 year old lady has some spotting and says she uses some steroid cream for a “rash down there”
A

Vulval cancer

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19
Q
  1. Lady is on Tamoxifen, which cancer does this increase the risk of?
A

Endometrial cancer

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20
Q

Green discharge points to which condition?

A

Trichomonas vaginalis (visualised on wet slide microscopy)

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21
Q

Woman with a slow growing painless lesion on labia

A

Bartholin’s cyst

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22
Q
  1. Woman who has gone through menopause, had a hysterectomy. Wants HRT mainly to prevent osteoporosis and treat her hot flushes. Doesn’t want to take tablets
A

Continuous transdermal oestrogen

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23
Q
  1. Woman with premature ovarian failure, wants to have periods
A

Cyclical combined HRT

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24
Q
  1. 62 y/o woman who just wants to treat osteoporosis
A

Bisphosphonates

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25
Q
  1. Small painful lump inside vagina of sexually active woman
A

Malignancy

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26
Q

Bleeding/unwell post partum- causes

A

Tone, trauma, thrombin, tissue

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27
Q

SBA on what to do with a cord prolapsed

A

push back the presenting part of the foetus

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28
Q

Anorexia diagnostic criteria

A

Anorexia nervosa - BMI <17.5 or 15% less than expected, deliberate weight loss, distorted body image, endocrine disturbance, may also purge
Refusal to maintain 85% of expected weight
Intense fear of gaining weight
Disturbed experience of body
Amenorrhoea

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29
Q

Bulimia diagnostic criteria

A

Bullimia nervosa - binge eating, purging, body image distortion, BMI > 17.5
Binging, purging both occurring twice a week for 3 months
Self evaluation overinfluenced by weight
Disturbance does not occur exclusively during periods of AN

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30
Q

Cardiac malformation in Turner’s?

A

bicuspid aortic valve, coarctation of aorta

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31
Q

What situation would you use donor eggs?

A

POI

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32
Q

What do you test for in Hep B infection antenatally?

A

Hep B surface antigen

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33
Q

What is the treatment for a bartholian abscess?

A

Marsupilisation

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34
Q

Women with APH (spotting) otherwise well, what is the most important thing to rule out?

A

Placental abruption

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35
Q

What type of contraception can increase risk of osteoporosis?

A

Progesterone only

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36
Q

When to admit Hyperemesis gravidarum?

A

Ketones and electrolyte imbalance. Dehydrated.

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37
Q

What is likely to cause this man’s azoospermia?

A

Variocele

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38
Q

Someone comes in at 28w with a Hb of 10.4 what would you do?

A

Give oral iron supplements?

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39
Q

Clue cells - what diagnosis?

A

Bacterial vaginosis

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40
Q

Strawberry cervix

A

Trichomonas vaginalis

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41
Q

Painful multiple lesions on labia

A

Genital warts

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42
Q

Mother with stillborn baby, generalized oedematous when born, mother had fever at 18w with rash on trunk

A

Varicella zoster virus

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43
Q

Smear comes back as moderate dyskaroysis

A

CIN?

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44
Q

76 year old had a single brown discharge - most likely diagnosis?

A

Atrophic vaginitis

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45
Q

Mother had previous CS, sudden abdo pain and abnormal CTG

A

Uterine rupture

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46
Q

Mother with girl who doesn’t speak, what should you do?

A

Hearing test?

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47
Q

Kid fitting for over 5mins, normal glucose, what do you give?

A

Buccal midazolam

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48
Q

Dehydration + ill kid (not DKA)– weight 15kg what do you give initially?

A

0.9% saline IV fluid bolus (20ml/kg)

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49
Q

Strawberry tongue (2 possibilities)?

A

Scarlet fever, Kawasaki disease

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50
Q

Child with pruritus ani worse at night, what would you give to treat? -

A

Single dose of mebdenazole to whole household

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51
Q

Impetigo treatment

A

Fusidic acid

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52
Q

Rash not involving flexures treatment?

A

Zinc and castor oil?

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53
Q

Rash involving flexures treatment?

A

Clotrimazole??

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54
Q

Chickenpox treatment

A

No treatment required

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55
Q

Posterior fossa tumour?

A

Medulloblastoma

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56
Q

Kid with sore throat, cervical lymphadenopathy, been given antibiotics, rash comes on.

A

EBV

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57
Q

Rash that started from behind the ears and spread to trunk, parents are vegetarians and kid goes to school in north London

A

Measles?

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58
Q

Scaphoid abdomen in a baby

A

Congenital diaphragmatic hernia?

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59
Q

Someone who just started on an antipsychotic and becomes tachycardia, hyperthermia, sweating, urine drug screen negative, what is the diagnosis?

A

Neuroleptic malignant syndrome

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60
Q

Diagnosed bipolar disorder – sudden renal failure, what do you check?

A

Lithium levels

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61
Q

Starting 21 year old with depression + suicidal idealization on antidepressants, what is your follow up plan?

A

Follow up in 1 week

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62
Q

Someone with acute dystonia what would you give?

A

Procyclidine

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63
Q

Alcoholic and had previous delirious tremens and wants detox at home what would you do?

A

Recommend hospital detox

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64
Q

78yo guy has issues with organization, troubles with understanding words

A

Frontotemporal dementia?

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65
Q

Women with sudden confusion what would you do first?

A

Urine dipstick

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66
Q

Failed 2 antipsychotics – what do you give?

A

Clozapine

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67
Q

Someone who was started on haloperidol and has acute muscle spasm (acute dystonic) ?

A

Give procyclidine

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68
Q

Lady has a diagnostic laparotomy. She has suprapubic pain that not even IV paracetamol is helping. What is the likely reason?

A

Perforation??

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69
Q

Somali lady comes in doesn’t speak much English says she’s 42 weeks. Examination of abdomen suggests a 32 week uterus. What is next in management?

A

USS scan?

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70
Q

Leading cause of maternal mortality in UK?

A

VTE??

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71
Q

Child is slow to get dressed. Likes to arrange his toys in a particular way

A

ADHD

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72
Q

Child is an arsonist. Gets in fights. Attacks teachers. What is he likely to have at age 20?

A

Antisocial personality disorder

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73
Q

Neonate. Ortolani test positive. What you do?

A

Hip USS at 6 weeks

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74
Q

Child has inspiratory stridor (doesn’t explicitly state, but gives a description implying this) since birth. Likely cause?

A

Laryngomalacia

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75
Q

7 year old goes to a new school. School complains that he keeps soiling himself. What is most likely reason?

A

encopresis

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76
Q

What defines a mild learning disability? [IQ: <80/<70/<60/<50/<30]

A

<70

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77
Q

You’re a GP. Elderly person presents with a history of the classical signs of Alzheimer’s. What do you do next?

A

Refer to memory clinic

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78
Q

A person with a diagnosis of Bulimia nervosa. BMI 22. Wants to get help. Management? [CBT; CBT+ Fluoxetine; Fluoxetine; Psychoanalytic therapy]


A

??

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79
Q

Two fetal poles, one gestational sac - what type of twins?

A

Monoamniotic; Dichorionic

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80
Q

MAOi cheese reaction?

A

Hypertensive crisis

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81
Q

Child with posterior rib fractures and some other patterns of injuries

A

NAI

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82
Q

Girl not able to weight bear. Recently recovered from viral illness.

A

Transient synovitis

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83
Q

Yellow-green discharge and pain - diagnosis?

A

PID

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84
Q

Commonest type of endometrial cancer?

A

Endometroid adenocarcinoma

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85
Q

Age of smiling?

A

6 weeks

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86
Q

When should children achieve pincer grip?

A

12 months

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87
Q

28 day child with pale stools

A

Biliary atresia

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88
Q

Child at school. Complains of unusual smell. Then seems to ‘space out’. Afterwards she’s very drowsy 
and sleeps for a few hours in the school nurses office. She has no recollection of what happened??

A

Focal seizure

89
Q

Redcurrent jelly stools - diagnosis?

A

Intussception

90
Q

19 year old abdo swelling, weight gain, irregular periods usually, can’t remember when last period was, denies being sexually active. What is the first test you would do?

A

Pregnancy test

91
Q

Woman with PCOS. Best medication to increase fertility.

A

Comifene

92
Q

Woman with signs of premature ovarian failure. What test would be best to confirm this diagnosis: Oestradiol, Testosterone, FSH, LH

A

FSH

93
Q

Man with azoospermia. What would be the most likely cause? Hx of mumps, hx of testicular torsion, Varicocele

A

Variocele

94
Q

What is a 23 week USS useful for? Nuchal thickness for Down’s, congenital heart disease identification, predicting position of placenta at term..

A

Congenital heart disease identification

95
Q

14 year old girl wants TOP, can’t/will not inform parents. What do you do?

A

Assess gillick competence

96
Q

Pregnant lady being domestically abused by husband and scared to go home. What do you do in GP? Send her home and ask her to come back with husband, give her a leaflet about domestic abuse, call and arrange emergency accommodation

A

call and arrange emergency accommodation

97
Q

Lady high White cell count, fever, lump in breast

A

Abscess

98
Q

General breast tenderness - left sided, breastfeeding

A

Mastitis

99
Q

Small painful lump inside vagina of sexually active woman

A

Genital wart

100
Q

Small slow growing lesion on labia, pregnant lady

A

Bartholin’s cyst?

101
Q

Kid who has acne. Topical Antibiotics don’t work. What do you give next?

A

Oral antibiotics + BPO

102
Q

Kid with history of anal fissure - what is your first cause of action?

A

Inspect anal region

103
Q

Kid has pain in outer ear, ear was protruding outwards, and there was a lump behind his ear.

A

Mastoiditis

104
Q

Kid with cervical lymphadenopathy, fever, sore throat, red tongue with white spots. What does she have?

A

Measles

105
Q

4yo kid having acute asthma attack, given iv salbutamol and hydrocortisone. Sats still low, no chest sounds on auscultation. What do you do/give next?

A

Call for senior help

106
Q

4 month old, about to have 3 batch of primary vaccinations. Which would be a complete contraindication to having the vaccine?

A

currently ill with a fever of 38.5

107
Q

Kid with URTI and generalised abdo tenderness

A

Mesenteric adenitis

108
Q

Baby was born at 41 weeks via emergency C section due to foetal distress. Needed ventilation straight away. X ray showed hyper inflated lungs with areas of consolidation. What does he have??

A

Meconium aspiration??

109
Q

Grandmother brings boy in with swollen knee. Boy’s brother died young of a minor head injury.

A

Haemophilia

110
Q

Treatment of scabies

A

permethrin cream and malathion lotion

111
Q

Risk of schizophrenia with family history

A

While the risk is 1 percent in the general population, having an FDR such as a parent or sibling with schizophrenia increases the risk to 10 percent.

The risk jumps to 50 percent if both parents have been diagnosed with schizophrenia, while the risk is 40 to 65 percent if an identical twin has been diagnosed with condition.

112
Q

60 year old woman, short term memory loss, struggling to complete her normal daily tasks, ataxia and dysphagia. What would you see on MRI? Hippocampal atrophy, lacunar lesions, white matter lesions, frontotemporal atrophy, general signs concordant with old age

A

Hippocampal atrophy??

113
Q

What is raised in anorexia nervosa?

A

growth hormone,glucose, salivaryglands,cortisol,cholesterol,carotinaemia

114
Q

What signifies onset of active labour?

A

4cm dilatation

115
Q

Woman has cervical cancer, is a smoker, hasnt had a smear for 8 years - what is the most likely contibuting factor?

A

No smears

116
Q

Woman with white discharge and itch. Which treatment

A

Clotrimazole pessary

117
Q

Pregnant woman with itchy feet, what investigation?

A

LFTs

118
Q

Results show azoospermia. How should they be managed?

A

IVF with ICSI

119
Q

Ground glass appearance of ovarian cyst

A

serous cystadenoma?

120
Q

Lady is on Tamoxifen, which cancer does this increase the risk of?

A

Endometrial??

121
Q

A newborn appears to be in severe respiratory distress and appears blue. Despite being given high flow O2, his saturations remain at 65%.
What is the next best step to take with regards to his management?
Chest X-Ray
Infusion of Prostaglandin
Surgery
Indomethacin

A

Prostaglandin E1??

122
Q

ADHD treatment

A

Parental training, methylphenidate, clonidine

123
Q

What is the most important thing to look at in follow up of HSP?

A

Urine protein and RBCs

124
Q

15 year old boy with short stature. Passing urine 10 times a day with no dysuria. Pale with heart rate at 78bpm, blood pressure at 158/88 and respiratory rate at 14. What is the likely diagnosis?

A

Diabetes??

125
Q

6 year old child with 24 hour history of left peri-orbital swelling. Had an upper respiratory tract infection last week. Left proptosis, visual acuity was normal and had a fever of 38.9. What is the best diagnostic investigation?
CT of nasal orbits, USS of nasal orbits, nasal endoscopy, intraocular pressure measurement, plain x-ray of nasal sinus

A

CT of nasal orbits

126
Q

Boy with itchy bottom, what do you prescribe?

A

Mebdenazole

127
Q

Child with 6m of loose stools. Passed one hard blood streaked stool 10 days ago. What investigation?

A

do nothing

128
Q

Infant with episodes of throwing arms forward with fists clenched.

A

Infantile spasm?

129
Q

Child with fever, white exudate on one tonsil, diagnosis? Tonsillitis, Quinsy, diphtheria

A

??

130
Q

Child with episodes of smelling strange things, hard to communicate with during these episodes, falls asleep for an hour after and doesn’t remember anything. Diagnosis?
Focal seizure, absence seizure, tonic clonic, narcolepsy

A

Focal seizure

131
Q

Mother worried 5 year old? son has autism. Which would most support a diagnosis of autism? Child doesn’t make eye contact, child didn’t speak first words until 2 years old and goes to a speech and language therapist, brings a particular toy with him everywhere

A

child didn’t speak first words until 2 years old and goes to a speech and language therapist

132
Q

Mother complains her young child is a fussy eater. She eats soft foods and drinks a lot of milk. Also has been feeling tired recently. Diagnosis?

A

Iron deficiency anaemia

133
Q

4 year old girl with a high fever that was followed by a rash which has small white dots on a red base. What is the most likely Dx?

A

Roseola infantum

134
Q

Child has an URTI 2 weeks ago. Has now developed a rash over the back of the legs along with joint and abdominal pain.

A

HSP

135
Q

Nappy rash with satellite lesions treatment?

A

1% hydrocortisone or anti-fungal cream

136
Q

Kid given dexamethasone for croup 12 hours ago by GP, was stable and well with good sats but still mild stridor. What else do you give?

A

Repeat steroids

137
Q

Hypochloraemic hypokalaemic pH shown, with some clinical information. What is the initial management for it?

A

Correct electrolyte imbalance

138
Q

Voraciously hungry kid, hypotonia and almond eyes what was the diagnosis? Initial problems feeding (big give away for prader-willi) and almond eyes.

A

Prader-Willi

139
Q

Kid who had rashes which had crusted over and he was also scratching them and now he had a peak fever and cool peripheries. What is the cause for his acute presentation?

A

Varicella zoster viraemia

140
Q

3 year old kid with unilateral nasal discharge with bleeding and crust or something like that, What was the most likely cause

A

Foreign body insertion

141
Q

Neonate with some cardio problem. Systolic murmur loudest at the left sternal edge 2/6

A

VSD

142
Q

Kid who basically had ADHD. What is the management? CBT, Parental training, methylphenidate.

A

Parental training

143
Q

14 year old kid who thieves, got into fights (basically conduct disorder). What is 1st Mx? Multisystemic (family) therapy, CBT, DBT, psychodynamic therapy

A

Multisystemic (family) therapy

144
Q

Child who has a hx of very dry skin, rash over arms, getting worse & spreading to ?extensor surfaces. Sister has itchy rash on ankles and wrists. (Sounds like Eczema) What would be the management? Fusidic acid, emollients+1% hydrocortisone, permethrin cream

A

emollients+1% hydrocortisone

145
Q

Hip pain on exercise and climbing stairs. Prolonged history, otherwise well. Perthes disease, osgood-schlater, septic arthritis

A

Perthes disease

146
Q

23yo female child with intermittent limp, otherwise well. DDH, irritable hip, osgood-schlater, septic arthritis

A

DDH

147
Q

Uncle gets TB, kid lives with him, Mantoux test showed a number between 10-14mm for the result. What should you do? Watch and wait, give Isoniazid prophylaxis, Start anti-TB treatment (the kid has TB with those diameters) give BCG vaccine, prophylactic isoniazid etc.u

A

Start anti-TB treatment (the kid has TB with those diameters

148
Q

Precocious puberty (5yo and has sparse axillary and pubic hair as well as breast bud development) and high centile growth parents are along some lower centile. What definitive diagnostic test do you do? Bone age, gonadotropin stimulation test, MRI scan of pituitary fossa

A

Gonadotropin stimulation test

149
Q

Cerebral Palsy (described hemiplegic weakness with brisk reflexes), what area of the brain is affected? Motor cortex, basal ganglia, pyramidal tracts, cerebellum, internal capsule

A

? Motor cortex

150
Q

Kid with 2cm x 2cm neck mass (inframandibular) on L side, painful, neck mass, reactive neutrophils - blood film shows: toxic left shift with reactive neutrophilia ?

A

Lymphadenitis

151
Q

Newborn with purple spot on face [Sturg-Weber], what is the next best approach? Discharge to Gp follow up, Medical photography, Clotting studies, Send urgently to A&E [MRI probably was a choice but not sure - don’t think so]

A

Medical photography?

152
Q

Kid needs fluids, but you can’t get standard IV access. Where do you go? Jugular, brachial, carotid, Intraosseous

A

Intraosseous

153
Q

HIV with undetectable viral load. what is contraindicated in labour?

A

Foetal blood sampling

154
Q

60 year old woman with PMB and superficial dyspareunia, what is the MOST LIKELY diagnosis?

A

atrophic vaginitis

155
Q

Mother had rupture of membranes at like 32 weeks. What do you give her? IM dexamethasone, magnesium sulphate, something that began with c

A

Dexamethasone

156
Q

Babies head comes out but it kinda goes back in. What is the cause?

A

Shoulder dystocia

157
Q

Woman with painful breast after giving birth. She’s breast-feeding - think she had abscess secondary to mastitis. Surgical excision, aspirate and ?culture, Ciprofloxacin

A

Ciprofloxacin

158
Q

Woman with blocked tubes, blocked tubes on hysterosalpingogram, what treatment should you do for fertility? IVF, IUI, ICSI.

A

IVF

159
Q

Poorly controlled diabetic mother, her newborn has an abnormal asymmetric Moro reflex - what’s wrong? (secondary to probably shoulder dystocia coz of diabetes) HIE, fracture of humerus, brachial plexus injury??

A

brachial plexus injury

160
Q

What procedure is contra-indicated in HIV pregnant woman?

A

Fetal blood sampling

161
Q

Woman at term has just SROM’d, transverse lie clear liquid but fetal distress, why?

A

Cord prolapse

162
Q

Old man who was ex-accountant has like MMSE 28/30, getting somewhat forgetful and needs wife to do his finances as he gets confused, but manages all other daily activities. what’s the diagnosis?

A

Mild cognitive impairment

163
Q

Some 25 year old students with asthma/diabetes, stressed about exams for 6 weeks and his exams are coming up in like 2 weeks. What do you do? watch and wait, CBT, beta blocker, benzo, sertraline

A

Give benzos

164
Q

Atypical anorexia nervosa?

A

All the symptoms but BMI >18.5

165
Q

50 year old guy wanders in screaming he sees ants and tiny men running around (buzzword), hot?, sweating, dishevelled looking - delirium tremens, cocaine ingestion, Wernicke’s

A

Delirium tremens

166
Q

Dude with LBD, given a drug that makes him worse, what drug?

A

Haloperidol

167
Q

Child has classic symptoms of ADHD, how do you manage? Methlyephenidate, Family Therapy or CBT

A

Family Therapy (first line ALWAYS)

168
Q

Some with dilated pupils, urinary retention, obs normal-ish - cause of overdose? TCA/amytriptiline, benzos, opioids, SSRI

A

TCA?

169
Q

50y lady fell over gardening, comes in with paralysis of leg, no medical cause found?

A

Conversion disorder

170
Q

Most common congenital infection in the UK?

A

CMV

171
Q

Investigations for ADHD:

A

Investigations:
Diagnosis only by a clinical psychiatrist
Includes psychometric testing
Include information from parents and teachers to ensure symptoms present in more than one aspect of life
Connor’s assessment scale may be useful
Educational psychologist assessment

172
Q

ADHD treatment

A

Stimulants, such as methylphenidate or dexamphetamine, and non-stimulants, such as atomoxetine, reduce excessive motor activity and improve attention on task and focused behaviour

173
Q

Follow up in ADHD medication

A

Height and weight measured in children every 6 months (3 months if under 10)
Measure CVD every 6 months
Sexual dysfunction, seizures, tics, sleep disturbances
Adherence difficult
Review treatment at least once a year

174
Q

Questionnaires for alcohol

A

Assess the pattern and severity of the alcohol misuse (AUDIT)
LDQ or SADQ for dependence
CIWA-Ar for severity of withdrawal
APQ for the nature and extent of the problems arising from alcohol misuse.
Consider MMSE for help in treatment planning

175
Q

Alcohol detoxification management

A

Detoxification:
Chlordiazepoxide to replace alcohol and prevent withdrawal symptoms
They are gradually withdrawn and stopped.

Thiamine: prescribed as prophylaxis against Wernicke’s encephalopathy.
Given parenterally (IM or IV) since it is poorly absorbed in the gut.

Symptom-led assessment is used, where medication is given according to observed withdrawal symptoms.
Outpatient detoxification indications 

Clinical evidence of alcohol withdrawal
Hx of alcohol dependence

Alcohol use greater than 10 units per day over the past 10 days
Inpatient detoxification indications

Acute confusion or symptoms of Wernicke-Korsakoff syndrome

Hx of seizures or delirium during withdrawals, comorbidities, malnutrition
Suicide risk high, history of polydrug use, comorbidities
Lack of stable support in community

176
Q

Alcohol relapse prevention

A

Psychological: CBT and problem-solving therapies
Medical: Acamprosate (anti-craving): enhanced GABA transmission in brain
S/E: pruritus, GI upset, rash
Disulfiram (Antabuse mimics flush reaction to alcohol)
Irreversible inhibitor of acetaldehyde dehydrogenase prescribed once abstinence is achieved
S/E: headache, halitosis, rarely liver toxicity

177
Q

Discuss oppositional defiant disorder.

A

Children should be younger than 10 years old and exhibit four behaviours from either the list below or up to two from the 15 item conduct disorder list above and the rest from the list below:
Has unusually frequent or severe temper tantrums for his or her developmental level
Often argues with adults.
Often actively refuses adults’ requests or defies rules.
Often, apparently deliberately, does things that annoy other people.
Often blames others for his or her own mistakes or misbehaviour.
Often ‘touchy’ or easily annoyed by others.
Often angry, resentful or spiteful

178
Q

Pharmacological treatment for conduct disorder?

A

Consider risperidone for the short-term management of severely aggressive behaviour in young people with a conduct disorder who have problems with explosive anger and severe emotional dysregulation and who have not responded to psychosocial interventions.

179
Q

Alzheimer’s (4 As)

A

Amnesia, aphasia, agnosia, apraxia

180
Q

Signs of frontotemporal dementia?

A

Change in behaviour and language difficulties

181
Q

Treatment of miscarriage?

A

Give anti-emetics and pain relief

182
Q

Follow up after medical miscarriage

A

Advise women to take a urine pregnancy test 3 weeks after medical management of miscarriage unless they experience worsening symptoms, in which case advise them to return to the healthcare professional responsible for providing their medical management.

183
Q

Follow up of expectant management for miscarriage <6 weeks without pain

A

To repeat a urine pregnancy test after 7–10 days and to return if it is positive
A negative pregnancy test means that the pregnancy has miscarried
To return if their symptoms continue or worsen.

184
Q

Manual vacuum aspiration is done where and when?

A

Before 14 weeks? Under LA in an outpatient or clinic setting

185
Q

Causes of Recurrent miscarriage = 3+ consecutive miscarriages?

A

Antiphospholipid syndrome
Endocrine disorders: poorly controlled diabetes mellitus/thyroid disorders.
Polycystic ovarian syndrome
Uterine abnormality: e.g. uterine septum
Pparental chromosomal abnormalities
Smoking

186
Q

Investigations for recurrent miscarriage?

A

Anti-cardiolipin antibodies, TFTs, HbA1c, prolactin, FSH/LH, transvaginal USS to rule out uterine abnormality, parental chromosome abnormalities, discuss lifestyle

187
Q

What to do if bleeding with CRL<7mm and no fetal heartbeat?

A

Refer for second opinion or re-scan in 1 week

188
Q

Questions in TOP?

A

Safeguarding, long-term contraception, STI screen,

189
Q

Medical treatment of TOP?

A

Oral mifepristone followed by misoprostol 24-48 hours later
Progesterone antagonist + prostaglandin
Pain relief for medical abortion
NSAIDS
N.B. If history of asthma can’t use prostaglandins
4-9w = mifepristone and one dose of misoprostol
9-24w = mifepristone and multiple doses of misoprostol

190
Q

13-24w = surgical management of TOP?

A

Dilatation and evacuation

191
Q

Diagnostic Criteria for LD:

A

Impairment of intellectual functioning
IQ <70 (2 SD from the mean)
Impairment in social or adaptive functioning
AoDL
Present before 18 years of age

192
Q

IQ parameters of LD:

A

IQ:
50-69 = mild
35-49 = moderate
20-34 = severe
0-20 = profound

193
Q

Most common inherited cause of LD?

A

Fragile X syndrome

194
Q

What is naltrexone?

A

Naltrexone (anti-craving): reduces total alcohol consumed and number of drinking days;
S/E: anxiety, headache, fatigue, flu-like symptoms, GI upset, sleep disturbance

195
Q

Questionnaires for PTSD

A

Impact of Event Scale (children’s version as well)
Post-traumatic Diagnostic Scale
Davidson Trauma Scale
PTSD Checklist

196
Q

What is the prognosis for the first instance of PP?

A

What is the prognosis for the first instance of PP?
Should resolve in 6-12 weeks
High risk of suicide
Risk of reoccurrence in subsequent pregnancies ~50%

What would be the main red flags for PP?
Feelings of harming self/ baby
Sudden change in mood/ mental state
Sudden change in attachment

197
Q

Drugs that can cause psychosis

A

anticonvulsants, high-dose corticosteroids, levodopa and dopamine agonists, or opioids

198
Q

Treatment for GAD?

A

Step 1 - education
Step 2 - low intensity psychological treatment
Step 3 - high intensity psychological treatment OR drug treatment

199
Q

15 year old boy with short stature. Passing urine 10 times a day with no dysuria. Pale with heart rate at 78bpm, blood pressure at 158/88 and respiratory rate at 14. What is the likely diagnosis? Chronic renal failure, diabetes mellitus, nephroblastoma, acute pyelonephritis, urinary tract infection

A

Chronic renal failure

200
Q

Child with fever, white exudate on one tonsil, diagnosis? Tonsillitis, Quinsy, diphtheria

A

Quinsy

201
Q

Amenorrhoea for 4 months - what do u do?

A

Beta HCG

202
Q

Asymptomatic woman, nulliparous, found to have a 5.4cm unilocular ovarian cyst on US, no fhx. Mgmt/Ix? USS guided cyst taspiration, laparoscopic removal of cyst, discharge and safety-net, rearrange USS in 3 months and Ca125 follow-up

A

rearrange USS in 3 months and Ca125 follow-up

203
Q

What causes increased urinary volume and frequency in the first trimester?

A

Increased GFR

204
Q

Small slow growing lesion on labia, pregnant lady

A

Genital warts

205
Q

Prem baby, resp distress, CXR looks like ground glass.

A

Respiratory distress syndrome (surfactant deficiency)

206
Q

80 year old man with new onset dementia, needs MRI but refuses. You need someone to make decision for him.

A

Independent mental health advocate

207
Q

Schizophrenia risk with family history

A

(1st degree relative is 1/10, a twin is 50%)

208
Q

Guy on medication for schizophrenia get muscle rigidity, altered consciousness, high blood pressure, tachycardia. Mgmt?

A

ITU admission

209
Q

Man with treatment resistant schizophrenia on clozapine, recently stopped smoking. High level of clozapine now. Most likely consequence?

A

Seizures

210
Q

How is removal of foreign body done?

A

Removal of foreign body under bronchoscope-guidance + antibiotics + bronchodilators. Then had to explain this to mum. Bronchoscopy

211
Q

What are the causes of oligohydramnios?

A

Renal agenesis
Multicystic kidneys
Posterior urethral valves
Placental insufficiency and FGR
Maternal drugs (NSAIDS)
Chromosomal abnormalities
Post-dates pregnancy
PPROM
Amnion nodosum
Intrauterine infection

212
Q

Criteria for learning disability

A

Lower intellectual ability (usually an IQ of less than 70). Significant impairment of social or adaptive functioning. Onset in childhood.

213
Q

What is the definition of a small for dates baby? How do we diagnose?

A

The estimated fetal weight or abdominal circumference of the fetus <10th centile for gestation – diagnosed on ultrasound

214
Q

What is the most common cause of SGA?

A

Constitutionally small (50-70% cases)

215
Q

Investigations for SGA

A

Screening for toxoplasmosis, CMV (malaria, syphilis if high risk travel)
Refer for umbilical artery surveillance every 2 weeks from 26-28 weeks
Measure EFW and AC every 2 weeks
Other surveillance: amniotic fluid maximum pool depth (<2cm = oligohydramnios), computerised CTG

216
Q

In SGA, At 31 weeks umbilical artery Doppler shows absent end diastolic flow – what next?

A

Continue UA surveillance daily and AC/EFW weekly
If DV Doppler is abnormal recommend delivery
If DV Doppler is normal, still recommend delivery by 32 weeks
Give steroids

217
Q

What is a DV doppler?

A

The ductus venosus (DV) is an intrahepatic end-part of the umbilical vein. Inappropriate first trimester DV Doppler blood flow patterns correspond to a higher risk of chromosomal abnormalities.

218
Q

If small for dates was picked up earlier (18-20 week scan) what investigations might you do?

A

Detailed fetal anatomical survey and uterine artery Doppler by fetal medicine specialist
Karyotyping if structural abnormalities or picked up before 23 weeks (may have trisomy 18 or triploidy)

219
Q

Cessation of smoking in pregnancy counselling:

A

Give her NHS Pregnancy Smoking Helpline
Refer to NHS Stop Smoking Services: structured self-help and support
NRT not recommended in pregnancy but can be given only if mother has stopped smoking
Offer CBT/motivational interviewing

Risks of smoking:
Miscarriage
Preterm delivery
Stillbirth
IUGR
Abruption
SIDS
Reduction in breast milk production
Jitteriness in babies in perinatal period (nicotine withdrawal)
More respiratory childhood infections

V Flashcards (17 decks)

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