O&G Flashcards

1
Q

What is the quickstart method for contraception? What is involved? Which methods not suitable for?

A

Starting outside of 1st 5 days, risk prengnacy. Do urine bHCG on day and repeat in 4 weeks, condoms for 7 days (3 for POP). Not safe for IUD + cyproterone COCPs.

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1
Q

What are the contraindications to the COCP? 9 categories.

A

6 weeks postpartum, Age >35 + smoking <>15 within 1 year, BMI >35, CVD risk factors (HTN except only in preg, IHD, AF, complicated diabetes), prev VTE or FDR < 45 w VTE or prolonged immobility or known mutations, migraine w aura (old migraines ok), BRCA carrier or breast ca, decomp cirrhosis/current GB disease/liver ca, antiphospholipid antibodies.

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2
Q

What contraception methods are safe in the setting of: postpartum, CVD risk factors, unexplained bleeding, prev breast ca.

A

PP: Implanon, depot, POP. CVD: Implanon, IUD, POP. Bleeding: COCP, POP. Breast ca: copper IUD only.

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3
Q

What medications can affect the efficacy of the COCP?

A

Rifampicin, antivirals, St John’s wort, carbamazepine, phenobarbitol, phenytoin, topiramate.

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4
Q

What are suitable contraceptive options for women over 45? How is this monitored?

A

Age 45 can insert mirena and keep till 55. From 50, avoid COCP and depot. IUD, POP, implanon okay. If no period, check FSH, if >30 can stop contraception in 12mo. Can stop contraception at age 55.

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5
Q

What are 2 forms of POP? How do they work? How long do they take to be effective? What is their window period?

A

Microlut (levonogestrel) - thick mucus + suppress ovulation 60%. 3 days to start, 3hr window (caution vomiting/diarrhoea). Slinda (drospirenone) - suppress ovulation. 7 days to start, 24hr window.

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6
Q

When is breastfeeding a viable form of contraception?

A

Amenorrhoea in 98% if 6mo postpartum, baby fully breastfed and no long intervals between feeds (4h day, 6hr night)

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7
Q

What supplements are recommended in early pregnancy?

A

Folic acid 0.5mg, 5mg if prev/Fhx neural tube defect, GDM, BMI >30, antiepileptic use; 1mo prior and for first 3mo of pregnancy. Iodine 150microg. Vitamin D 400U recommended, check if risk factors.

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8
Q

What tests are recommended in early pregnancy?

A

FBE, fasting BSL, HIV, Hep B, syphilis, rubella, urine MCS + proteinuria, chlamydia < 25 or high prevalence, genetic carrier screening, CST if due. Hep C if risk factors, Vit D if risk factors, gonorrhea/trichomonas/BV if symptoms/risk, CMV if children around, TFTs if risk.

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9
Q

What tests are done to look for chromosomal abnormalities during pregnancy? When? Risks?

A

NIPT from 10 weeks. Combined FTS from 9/11 - 13+6, screen for T18, 21 and 13. 2nd trimester screen from week 14. Diagnostic tests are CVS weeks 11-13, amniocentesis from week 15, 1% risk of miscarriage.

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10
Q

Which pregnant women are screening for thyroid disease, vitamin D and iron deficiency?

A

T: PHx, FHx, autoimmune diseases, prev miscarriage/infertility, goitre. D: dark skin, south lattitude, low sunlight exposure, obesity. I: ATSI, immigrant, vegetarian.

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11
Q

How are back, pelvic pain and N/V managed in pregnancy?

A

BP: common, fitness/strengthen, panadol. P: strength/stabilise, fitness ball, water based exercise. NV: pyridoxine 12.5mg BD , add doxylyamine 25mg at night. 2ndline :maxalon, ondans, stemetil (cat C)

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12
Q

How are psychotropics in pregnancy counselled - benefits, risks, strategies. Which drugs need an urgent plan?

A

B: reduce neglect, harm/distress ofmother. R: preterm, congenital abnormalities, IUGR, neonatal adaptation in serotonin. Aim low doses, avoid polypharmacy, avoid abrupt cessation and rec 2nd trimester scan + observation of neonate postpartum. Lithium, carbamazepine, valproate.

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13
Q

What are 4 considerations of SSRIs in pregnancy? Which is safest? Which are least safe and for breastfeeding?

A

Association w poor growth (not proven), possible teratogen/cardiac malformation/miscarriage (paroxetine, venlafaxine), neonatal adaptation, persistent pulmonary hypertension - very slight risk. Sertraline safest. Fluoxetine highest conc in milk. Don’t start fluoxteine or parox, but may cont if already started, dw patient.

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14
Q

What are 3 points of discussion in an unplanned pregnancy?

A

Confidential unbiased nondirective counselling, screen for abuse, 1800myoptions for information.

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15
Q

What are 6 causes of early pregnancy bleeding? What investigations are done?

A

Implant bleed (2wk from ovulation), miscarriage, ectopic, cervical or vaginal (infection, ca, polyp), uterine infection, perigestational haemorrhage. Rarely molar pregnancy. Serial bHCG (48-72hr) transvaginal U/S (visible if bHCG >1500/2000), blood group/antibodies.

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16
Q

What are 7 minor and major causes of antepartum haemorrhage? Definition and other ddx?

A

Min: marginal placental bleed, cervical ectropion, blood-stained show. Maj: placental abruption, placenta praevia, vasa praevia, uterine rupture. Bleed >20wk. DDx: UTI, haemorrhoid.

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17
Q

How is an antepartum haemorrhage managed?

A

Lie supine w lateral tilt, IV access, rapid fluid resus (may need blood), monitor vitals + FHR + CTG, do U/S before any speculum/digital exam incase of praevia.

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18
Q

What are the risk factors + sx for placenta praevia and placental abruption?

A

PP: prev c-section/uterine surgery, prev praevia, advanced age. Painless bleeding. PA: trauma, smoking, cocaine, HTN, PROM. Bleeding, tenderness and possible contractions.

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19
Q

What are the risk factors for pre-eclampsia? Risks of pre-eclampsia?

A

RF: prev preeclampsia, HTN, pre-existing diabetes, SLE, antiphospholipid syndrome, obesity, CKD. M: seizures, renal failure, DIC, pulmonary oedema, HELLP. F: IUGR, preterm delivery, death.

Consider aspirin from 12 weeks.

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20
Q

What is pre-eclampsia? What are severe symptoms? What tests are indicated?

A

New HTN after 20 weeks + involvement of renal/haem/liver/neuro or pulm oedema or IUGR. Headache, visual changes, RUQ pain, altered mental status, dyspnoea/oedema. Ix: FBE, UEC, LFT, urine ACR, U/S.

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21
Q

What is gestational hypertension vs chronic hypertension? How is this managed in pregnancy?

A

HTN after 20 weeks or before. Screen for preeclampsia. 1st line: labetalol, methyldopa

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22
Q

What are 12 things to consider in a 6 week post partum check?

A

Pregnancy complications, labour/delivery, perineal tears, lochia, breastfeeding, bowel/urinary issues, sleep, mood - EDPS, return to exercise (walk, avoid high impact 3mo), sex - contraception, cervical screening, rubella ok in breastfeed but delay 6mo from transfusion.

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23
Q

Post partum endometritis - timing, DDx, tests, mx.

A

Within 1 week, infected RPOC, PID ?septic aborption. Ix: U/S, blood cultures, endocervical swab MCS + PCR (C, G, Myco). Rx: augmentin or bactrim + metro. Severe: IV gent, metro, amoxicillin.

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24
Q

What are 4 signs of adequate breast milk supply? What can help?

A

Growth (150g per week, birth weight by 2w), 5-8 wet nappies, passing stool at least once per day, settled between feeds with good tone/skin. Hold skin to skin, breastfeed freq (2-3h), review attachment, express after feeds, lactation consultant, rarely domperidone (EPSE, long QT).

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25
Q

What are 6 causes of pain with breastfeeding? How is the most common managed?

A

Thrush, mastitis, milk blister/white spot, blocked duct, dermatitis, poor attachment/trauma - lanolin cream, panadol, avoid tight bra, review attachment/lactation consultant, feed from other side first, rest for 1-2 feeds: pump from affected side.

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26
Q

Lactational mastitis - 4 nonpharm mx, pharm mx and indication.

A

Breastfeed as usual (feed from affected first to drain), covered cold packs 10min/hr, gentle massage to axilla for lymphatics (no deep/firm), lactation consultant review attachment. If systemically unwell or not improve in 48hr, fluclox/diclox 5-10d. Keflex if allergy, clinda if severe.

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27
Q

How is breastfeeding reduced - wean and post abortion?

A

Aim to drop feeds per day by 1 per week, express only for comfort but avoid excess. In abortion, cabergoline 1mg stat + tight bra.

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28
Q

Symptoms/signs of nipple thrush and management.

A

Burning stinging pain, persists after feed, tender to light touch. Pink/shiny nipple or flaky. Baby: daktarin QID then D (2wk). Mum: oral fluconazole 3 doses over 1 week then oral nystatin TDS and daktarin gel to nipple QID for 1 week.

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29
Q

Risks of PND? Diagnosis. 5 aspects of management.

A

Suicide, infanticide, psychosis. EPDS >13. Optimise supports (carer cert), parent infant therapist - PANDA, crisis lines, psychology - CBT first line, if severe use sertraline.

30
Q

What tests/workup indicated in decreased foetal movements?

A

After 28 weeks. Do abdo exam, symphysis fundal height, BP. FHR w doppler. Need CTG within 2 hours and U/S within 24hr - urgent hospital. Don’t use kick charts.

31
Q

What is recurrent pregnancy loss? What workup is indicated and for what causes? Advice for parents.

A

2 losses. Karyotype of POC +/- parents for genetic (eg. chromosomal anomaly); U/S for fibroid or septate uterus; screen for hypothyroid, diabetes, thrombophila (antiphospholipid - lupus anticoag + cardiolipin Abs). Avoid drugs/alc/smoking, healthy BMI, < 3 cups coffee.

32
Q

What is the ovulation window? What female causes are of infertility are considered and when/how is testing done?

A

5d before + day of ovulation (14d before period, daily/2nd daily intercourse. PCOS, endometriosis, PID/STI, prolactinoma, early menopause. Ix after 12mo or 6mo if > 35yo –> Day 2 FSH, LH, oestradiol; AMH level, TSH, U/S pelvis - anatomy, follicle count, endometriosis.

33
Q

What are causes of primary and secondary amenorrhoea?

A

No period age 15/16: constitutional delay, ovarian dysgenesis (Turner), imperforate hymen or mullerian agenesis. Both: Hypothalamic (stress/illness/exercise); pituitary (prolactin), hypothyroid, PCOS, pregnancy, Secondary: early menopause, adrenal (CAH, cushings), meds (OCP, antipsychotics - prolactin, chemo).

34
Q

What exam and investigations are indicated for amenorrhoea?

A

Height - turners, acne/facial hair PCOS, galactorrhoea (prolactin), hypothyroidism, BMI, systemic illness. FSH, LH, oestradiol, TSH, prolactin, U/S, pregnancy test.

35
Q

What is secondary dysmenorrhoea? Presentation, possible causes and mx.

A

Pain from a disorder, not physiological. Later in life, change in pattern, Fhx of endo, dyspareunia or IMB. Endo, adenomyosis, fibroid, PID, cervical stenosis. Mx: Contraception, NSAID (ibuprofen, ponstan, naproxen for 2-3d). 2nd: heat, TENS, acupuncture.

36
Q

What are the possible causes of intermenstrual bleeding? 9

A

Polyps, adenomyosis, leiomyoma, endo/cervical ca, coagulopathy, ovulatory dysfunction. Cervicitis/endometritis - STI, thyroid dysfunction, cervical ectropion.

37
Q

What tests/workup for intermenstrual bleeding?

A

Pregnancy, co-test, STI screen. If 1 episode of post-coital and normal cotest then stop. If more than 1 or not post-coital, do colposcopy/refer. If persistent and risks consider coags screen + U/S for endometrial thickness (max 4mm post, 5mm peri, 12mm pre).

38
Q

Investigations and management of menorrhagia?

A

Pregnancy, CST if due, FBE/ferritin +/- coags, TSH. No hormones if cyclical. If persistent 6mo or pain for 3mo or concern re endo/fibroids, do U/S. Mx: IUD first line, NSAID, tranexamic acid, OCP, cyclical POP. Acute: tranexamic acid or medroxyprogesterone 10mg 4-8hr or norethisterone.

39
Q

What are the indications for referral for menorrhagia?

A

Not responding 6mo, fibroid >3cm, severe pain, fertility planning eg endo, risk of ca - PCOS w oligomenorrhoea, obestiy, age >45, unopposed oestrogen use, thick uterus (>12mm pre, >5 peri).

40
Q

What are the non-hormonal/pharm options for menopausal symptoms?

A

CBT, mindfulness, hypnosis for vasomotor, weight loss if overweight, cooling techniques. Flushes: SSRI/SNRI (escitalopram, desvenlafaxine), gabapentins also help w sleep/pain, clonidine.

41
Q

What are the contraindications to systemic HRT? What are the contraindications to oral HRT?

A

Starting age >60, prev VTE/TIA/AMI, uncontrolled HTN, oestrogen dependent ca (breast/endometrial) or undiagnosed bleeding, high risk of breast ca, significant liver disease, SLE. Oral: risk factors for VTE/CVD (obesity, smoking, diabetes, HTN), liver/gallbladder disease.

42
Q

What are the 4 hormonal treatment options for HRT?

A

Oestrogen only (no uterus). Combined cyclical if perimenopausal. Combined continuous if >1y since period or on cyclical for 1 year w less bleeding. Tibolone - synthetic steroid, risk breast but not assoc w VTE.

43
Q

How is HRT reviewed - titration, bleeding.

A

Review 6-8 weeks then 6mo. Increase oestrogen if flushes ongoing. Cyclical: Bleeding should occur after day 10 of progesterone (if not, increase dose). Cont: can get breakthru bleeding for 3-6mo. Only ix if heavy, postcoital or high risk.

44
Q

5 causes of post menopausal bleeding? What are baseline tests?

A

Endometrial ca, endometrial polyp, endometrial hyperplasia w HRT, atrophic endometritis/vaginitis, cervical cancer. Cervical co-test, U/S.

45
Q

What are risk factors for endometrial cancer (warrant gynae for post menopausal bleeding)? What will gynae do and when?

A

Chronic anovulation, PCOS, unopposed oestrogen, tamoxifen use, Strong Fhx of endo/colon ca (Lynch syndrome), nulliparity, endometrial thickness >4mm, obesity. Endometrial biopsy with/wo hysteroscopy, within 6 weeks.

46
Q

Urinary incontinence history - symptoms, risk factors, associated conditions.

A

Stress or urge. RF: parity, vaginal deliveries, chronic cough, constipation, smoking, alcohol/caffeiene/sweeteners, high impact exercise. Assoc: UTI sx, bowels, haematuria, limb weakness/saddle, prolapse sx, diabetes, NPH (gait, confusion)

47
Q

7 exam findings and 5 investigations to consider in urinary incontinence?

A

Palpable bladder, atrophic vaginal mucosa, cough test, prolapse, constipation, lower limb neuro, CCF signs. Bladder diary recommended (hold 400mL day, 800 night), exclude UTI, diabetes, consider U/S renal tract + urine cytology.

48
Q

What are 7 aspects of non-pharm management of overactive bladder?

A

Healthy weight, treat constipation, optimise fluid intake, reduce stimulants (coffee, alcohol), use pads, pelvic floor strengthening w physio (avoid cough/weights), bladder training - scheduled voiding

49
Q

What are 3 medications to help treat overactive bladder - frequency, mode, SE.

A

Oxybutynin TDS (non-selective anticholinergic) - dry mouth, blurred vision, constipation, delirium. Solifenacin (selective anticholinergic) - hepatic impairment. Mirabegron (beta 3 agonist) - HTN, long QT.

50
Q

Features of bartholins cysts/abscess and management.

A

Cysts 1-3cm, not painful. Sitz baths or warm compress, may drain if large. Abscess - >3cm or pain/inflamed, from piercing, STI, skin infection, hair. Abx, sitz, incision.

51
Q

Causes of vulvovaginitis - 5 dermatoses, 4 infections and 2 others.

A

Irritant dermatitis, atopic dermatitis (eczema), lichen sclerosus, lichen planus, psoriasis. Candida, herpes, BV (grey, smelly) trichomonas (itch, frothy fishy green). Atrophic vaginitis, provoked vestibulodynia.

52
Q

How is vulvovaginal candidiasis treated? - nonpharm, pharm, recurrence, ddx.

A

Take swab. Loose cotton underwear, avoid sprays/soaps, wash hands before touching, gentle wipe dry. Clotrimazole 1% 6 nights or 100mg 6nights or 10%/500mg 1 night. Alt: nystatin cream, oral fluconazole 150mg. Recur if >3 in a year: fluconazole 3 doses then weekly for 6mo. DDx: candida glabrata, use nystatin.

53
Q

Features of lichen sclerosus, associations, risks, management.

A

White sclerotic/shiny, itchy patches, may be painful/blistered in figure 8 around anogenital. Assoc: autoimmune (thyroid, vitiligo). R: labial fusion/phimosis, dyspareunia, SCC 5%. Refer - can do biopsy, high dose topical steroid, monitor for cancer yearly.

54
Q

Causes of vulvodynia (4 categories), mx.

A

Lube: poor arousal, fear, hormone (age, breast feeding). Skin - UTI, eczema, thrush. Vaginismus (tightness): from prev trauma/infection. Deep: endo, fibroids, PID, prolapse. Mx: avoid painful sex, avoid irritants, can use topical lidocaine and see vulval spec. Vaginismus: education, pelvic floor physio, psychology, systemic desensitisation w dilators.

55
Q

How is CST performed around pregnancy? Young people < 25?

A

Use cytobroom/swab (no brush). If positive, do culposcopy for invasive disease. Post pregnancy recommended from 6 weeks, usually done at 3mo for good cervical cells. If sex < 14 (before HPV) OR immunosuppressed 5 years, do screen.

56
Q

What CST is recommended in older women? Immunosuppressed? Post hysterectomy?

A

From 70 either test, if neg cease, if +ve do colposcopy. If severe immunosuppression, screen 3y and colposcopy if +ve. Hysterectomy from HSIL - cotest for 2 years. Subtotal hysterectomy, screen as usual. Others, don’t need.

57
Q

What features are diagnostic of PCOS? What tests are used in the workup of PCOS?

A

Oligoovulation, hyperandrogen, polycystic. Bloods if no clinical androgens: total testosterone, FAI, LH/oestradiol/progesterone for phase, 17 progesterone for CAH, TSH, prolactin, bHCG for others. U/S if >8y post menarche for at least 12 follicles if bloods not diagnostic.

58
Q

What are 6 aspects of PCOS management? What are the risks?

A

Aim BMI < 25, emotional support, regulating periods/reducing androgens, fertility, metformin if high BMI or T2DM as adjunct. Risks: T2DM (do OGTT), OSA, depression, high cholesterol, CVD risk, endometrial hyperplasia.

59
Q

What are 4 options to help manage periods in PCOS? Benefits?

A

COCP most effective, mirena, cyclical progesterone (short term only), metformin may help as adjunct. Need to counter anovulatory cycles which lead to high oestrogen - reduce cancer risk. Aim for 4 periods per year unless on OCP.

60
Q

What is first line management of infertility in PCOS? What can GPs and specialists do?

A

Lifestyle - diet, exercise, 5% weightloss if overweight. Can add metformin esp BMI >30, while waiting. Specialist: letrozole, gonadotrophins, drilling, IVF.

61
Q

Ovarian ca - risk factors, protective, symptoms, exam findings.

A

Fhx, Fhx breast/colon/uterine ca, BRCA gene or lynch syndrome, nulliparity, smoking, HRT. Prot: COCP, parity, breast feeding. Sx: bloating, early satiety, urinary freq/incontinence, abdo pain, fatigue. Ex: mass, ascites, lymphadenopathy, effusion

62
Q

What tests may be indicated in someone with risk factors for ovarian cancer? What are suspicious features on US (4)?

A

Screening for breast and colon cancer. In post menopause, U/S and Ca125 helpful. Solid area, ascites, papillary structures, blood flow.

63
Q

Breast lump - history features, assessment.

A

Hormone history, Fhx breast/ovarian ca, weight, alcohol, smoking. Lump exam (size, shape, location, consistency, mobility, tenderness); U/S if < 35, U/S + mammogram if >35. Non-excisional/core biopsy. Triple test for all lesions and refer if abnormal.

64
Q

Features and causes of pathological nipple discharge. Management.

A

Unilateral, single duct, spontaneous, bloody. Papilloma (benign but can have atypical area), duct ectasia - benign, older women. Cancer 5-15% usually DCIS. Infection - mastitis. Do mammogram + U/S.

65
Q

Features and causes of benign nipple discharge, workup.

A

Bilateral, milky, multiple ducts, maybe yellow/green. Most from prolactin (tumour, hypothyroid, drugs - antipsychotic, maxalon). Others: eczema, pagets disease. bHCG, TFT, UEC, prolactin level and do imaging (unless resolved and obv benign). If antipsychotic, use aripiprazole (psych to do)

66
Q

What are possible presenting symptoms of endometriosis? When is referral indicated?

A

Pain, dysmenorrhoea, dyspareunia, period/cyclical GI symptoms OR urinary symptoms, infertility. Refer if significant sx, seeking fertility, bowel/bladder involvement, mass/nodule or sx not responding to 3mo of painrelief +/- hormones.

67
Q

What are risk factors for an ectopic pregnancy? What are 3 signs of ruptured ecoptic?

A

Prev ectopic, prev tubal surgery, sterilisation or IUD, IVF, prev STI/PID, smoking, OCP. Do speculum - blood and/or cervical motion tenderness, peritonism, shock.

68
Q

How is rubella and pertussis exposure managed in pregnancy?

A

R: check IgG and IgM, high risk in 1st trimester, consider abortion. Rare risks after 16wk. P: if close contact w infectious person within 2 weeks, and last month of pregnancy, treat prophylactically.

69
Q

How is varicella exposure managed in pregnancy?

A

Exp if living together, F2F contact 5 min or 1hr in same room. If prev VZV, no treatment. If unsure, check VZIG levels - give ZIG within 96hr or up to 10d if no prev immunity. If after 96h from exposure, consider antiviral therapy for 2nd half of pregnancy.

70
Q

Pelvic organ prolapse risk factors(7), mx options (8).

A

Pregnancies (assissted + vaginal), menopause, age, constipation, chronic cough, obesity, smoking. Mx: weight loss, avoid lifting, smoking cessation, treat constipation, pelvic floor muscle training. Ring pessary, topical oestrogen post menopause (may reveal urine incontinence). Surgery 2ndline due to risks.

71
Q

How is a medical termination of pregnancy achieved? When can it be done? What are contraindications?

A

Mifepristone (stops pregnancy), misoprostol (induce labour,take 24-48hr after). Bleeding 3h later for 10-16d. Must be within 2h from hospital, < 9 weeks gestation and intrauterine (need U/S first). C/I: long term steroids, chronic adrenal failure, coagulopathy.

72
Q

What is premature ovarian insufficiency? Risks, Ix and treatment.

A

Amenorrhoea before 40. Risks: symptoms, bone loss, CVD, infertility, autoimmune conditions. Check elevated FSH, DEXA, TFTs, CVD risk. Rec treating with oestrogen until age 51 unless cancer –> OCP or MHT w progesterone or MHT w mirena.

73
Q

What are 3 benign cervical abnormalities? What 3 cervical changes need referral?

A

Ectropion - columnar epithelium visible. Nabothian cyst/follicles (yellowish mucous retention cyst). Atrophy post menopause - wider, pale. Polyp if >3cm or atypical, any bothersome changes (pain/bleeding), warts + leukoplakia risk malignancy.