Nutrition I

Question 1

fat soluble vits

Answer 1

A, D, E, K

Question 2

vit B1

Answer 2

thiamine

Question 3

vit B2

Answer 3

riboflavin - FAD, FMN

Question 4

vit V3

Answer 4

niacin - NAD+

Question 5

vit B5

Answer 5

pantothenic acid - CoA

Question 6

vit B6

Answer 6

pyridoxine - PLP

Question 7

vit B7

Answer 7

biotin

Question 8

vit B9

Answer 8

folate

Question 9

vit B12

Answer 9

cobalamin

Question 10

vit C

Answer 10

ascorbic acid

Question 11

vitamin storage

Answer 11

all wash out easily from body - water soluble

except B12 and folate - stored in liver

Question 12

vitamin A

Answer 12

retinol
-antioxidant

essential for normal differentiation epithelial tissue into specialized tissues

Question 13

prevent squamous metaplasia

Answer 13

vit A

Question 14

vit A source

Answer 14

liver and leafy veggies

Question 15

vit A deficiency

Answer 15

night blindness - nyctalopia

dry scaly skin - xerosis cutis

corneal degeneration - keratomalacia

Question 16

vit A excess

Answer 16

acute - nausea, vomit, vertico, glurry vision

chronic - alopecia, dry skin, hepatotoxic, teratogenic

Question 17

isotretinoin

Answer 17

vit A derivative
-acutane

need negative pregnancy test before use for acne - because teratogenic

Question 18

vitamin B1

Answer 18

in TPP - cofactor for several DH rxns

pyruvate DH - glycolysis to TCA
a-KG DH - TCA cycle
transketaolase - HMP shunt
branched chain ketoacid DH

Question 19

beriberi

Answer 19

vit B1 deficiency

Question 20

wernicke korsakoff syndrome

Answer 20

vit B1 thiamine deficiency

confusion
ophthalmoplegia
ataxia

also - memory loss - damage medial dorsal nucleus of thalamus and mamillary bodies

Question 21

dry beri beri

Answer 21

vit B1 thiamine deficiency

-polyneuritis - symmetric muscle wasting

Question 22

wet beri beri

Answer 22

vit B1 thiamine deficiency

• high output cardiac failure
• dilated cardiomyopathy
• edema

Question 23

diagnosis thiamine deficiency

Answer 23

vit B1

measure RBC transketolase activity after B1 admin

Question 24

vit B1 deficiency

Answer 24

impaired glucose breakdown - loss of ATP

bad for brain and heart

Question 25

vitamin B2

Answer 25

riboflavin cofactor for redox rxns succinate DH in TCA cycle FAD and FMN

Question 26

vit B2 deficiency

Answer 26

cheilosis - inflammation of lips, scaling and fissures corners of mouth corneal vascularization

Question 27

vit B3

Answer 27

niacin constituent of NAD+ and NADP+

Question 28

tx dyslipidemia - raise HDL, lower VLDL

Answer 28

niacin - bit V3

Question 29

vitamin B3 deficiency

Answer 29

glossitis pellagra

Question 30

pellagra

Answer 30

vit B3 niacin deficiency 3 D's: diarrhea dementia dermatitis dermatitis - C3/4 dermatome broad collar rash and hyperpigmented sun exposed skin

Question 31

excess vit B3

Answer 31

facial flushing due to prostaglandin avoid - take aspirin with niacin

Question 32

vit B5

Answer 32

pantothenic acid component of CoA deficiency - dermatitis, enteritis, alopecia, adrenal insufficiency

Question 33

vit B6

Answer 33

pyridoxine converted to PLP cofactor lots of rxns synthesis of cystathione, heme, niacin, histamine, serotonin, E, NE, dopamine, GABA

Question 34

deficiency vit B6

Answer 34

pyridoxine convulsion hyperirritable peripheral neuropathy sideroblastic anemia

Question 35

vit B7

Answer 35

biotin -cofactor carboxylation enzymes deficiency - eat too many egg whites

Question 36

eat too many egg whites

Answer 36

vit B7 deficiency - biotin dermatitis, alopecia, enteritis

Question 37

vitamin B9

Answer 37

folate converted to THF important synthesis of nitrogenous bases of DNA and RNA

Question 38

vit B9 deficiency

Answer 38

folate macrocytic megaloblastic anemia hypersegmented PMNs glossitis lab - elevated homocysteine normal methylmalonic acid MC vit deficiency in US - alcoholic and pregnant

Question 39

supplement folate

Answer 39

vit B9 pregnant women prevent neural tube defects

Question 40

folate vs. B12 deficiency

Answer 40

folate - no neuro sx B12 - neuro sx both have megaloblastic anemia