nutrition for the sick patient Flashcards
How do we detect malnutrition?
- MEDICAL & DIET HISTORY:
– Physiological status: reproduction, age, activity
– Persistent GI signs: nausea, vomiting, diarrhea
– Disease history: Concurrent diseases may:
> Worsen without nutrition support
> Inhibit food intake for long time
– Diet history: homemade, limited ingredient, therapeutic, etc. - PHYSICAL EXAM:
– Significant weight loss
– Evidence of muscle wasting
– Depletion of subcutaneous fat
– Poor hair coat, discolouration - Lab work
wiehgt loss or BCS indicative of malnutrition
Weight loss > 10% in 1 wk
BCS < 3/9
MCS < mild muscle loss
Who should receive nutritional support?
- Patients already with malnutrition
- Patients at risk of malnutrition
- Inappetant
> Not eating for 48 h
> Food intake < RER for > 3 d - Concurrent disease
- GI dysfunction
food deprivation - what is used for endogenous fuel
- Glycogen
- Fat tissue
- Muscle protein
> Fuel to meet metabolic needs
> Maintain blood glucose
cachexia:
- mechanism
- appetite
- effect of feeding
- metabolism
- thyroid
- body energy stores
- mechanism: chronic illness
- appetite: decreased
- effect of feeding: does not change appetite, may maintain body weight but lean losses continue
- metabolism: no change to increased
- thyroid: no change to increased
- body energy stores: use fat or muscle for energy, but seems to be a preference for muscle breakdown
cachexia is driven by
catecholamines, glucocorticoids, glucagon, inflammatory mediators
complications of protein malnutrition
- Ileus & Bacterial translocation > Sepsis
- Immunity ↓ - infection risk ↑
- Tissue synthesis & repair ↓
- Drug metabolism > risk for activity and overdose
> Hepatic biotransformation ↓
> Binding & transport ↓
> Renal blood flow ↓ - Elimination↓
- Not always appropriate to feed a therapeutic diet in hospital because
learned food aversion
Every day without adequate nutrition impacts recovery how?
3-5 days extra for recovery
when should we make sure a sick patient is eating?
ASAP
GOAL - Within 24-48 h of hospitalization
- Hemodynamically stable
what to feed the hospitalized patient?
KNFs
PROTEIN
* Protein requirement ↑ (2-3 x > healthy)
Dog ~3g/kg BW0.75
FAT
- efficient energy source
CARBOHYDRATE
* Less efficient as energy source
* Adverse effects: DIARRHEA, HYPERGLYCEMIA
why do hospitalized animals need more protein? cautions?
- Protein breakdown ↑
- protein synthesis ↑
- GOAL
- Protein synthesis ↑
- Spare endogenous muscle protein
- Essential AA and amino groups acute phase proteins / immune response
- caution if:
- liver or renal dz
> if less than RER high protein can be ok
caution feeding more fat to hospitalized patient if
Pancreatitis
Hyperlipidemia
Diarrhea
Vomiting
> If less than RER, Moderate/high fat diet can be OK!
purpose of fat in hospital diet
- Much more efficient (> 2x calories/volume)
- Calorically dense > smaller volume
- Shift glucose to fat metabolism
> Metabolic complications ↓
> CO2 production ↓
adverse effects of carbohydrate in hostpital diet
Malabsorption > DIARRHEA
- Dehydration
- Acid/base & mineral balance
- Contamination of wounds
- Colonic fermentation ↓
- Butyrate production ↓
()
Altered glucose control > HYPERGLYCEMIA
- Osmotic shifts: Refeeding syndrome
- Glucosuria
- Altered immune function
- Predispose to infection
- Oxidative stress / damage
- Respiratory work ↑ (CO2)