Nutrient Compounds

Question 1

Se

Answer 1

DNA protection, repair, induction of cell cycle arrest

Question 2

Soy Isoflavones

Answer 2

phytoestrogens that alter hormone regulation. Genistein and daidzein can bind to estrogen receptors.

Question 3

Curcumin

Answer 3

Turmeric: induces apoptosis and inhibit angiogenesis

Question 4

Indole-3-carbinol

Answer 4

Cruciferous vegetables: influences estrogen regulation, induce cell cycle arrest, inhibit angiogenesis, and suppress inflammation

Question 5

Sulforaphane

Answer 5

Compound in cruciferous vegetables may inhibit carcinogen formation and induce apoptosis.

Question 6

Allyl Sulfer

Answer 6

Found in Garlic may block formation of carcinogens, enhance DNA repair, reduce proliferation and induce apoptosis.

Question 7

Folate

Answer 7

Adequate intake= lower chance of developing many cancers. Can provide substrates for DNA synthesis and accelerate tumor expansion. Anti folate chemo drug Methotrexate acts on this. Patients require calcium leucovorin (a form of folate) for toxicity.

Question 8

Nutrients and DNA

Answer 8

DNA repair= folate, se
Apoptosis= Se, curcumin
Prevent damage= Vit C/ E

Question 9

ECGC

Answer 9

reduces inflammation and cell differentiation. Drinking tea can raise antioxidant ability.

Question 10

Flaxseed

Answer 10

Plant lignins, and ALA/ Omega 3. May reduce BC risk but depends on the person. ? enhance Tamoxifen in mice