NURS444 Cardio Flashcards
Define Cardiovascular disease
Alteration in the heart leading to alterations in blood flow (Q) and P
What are the most common Cardiovascular Diseases? (6)
Hypertension - HT Coronary heart disease- CHD Heart failure - HF Cerebrovascular disease - CVD Myocardial ischaemia - MI Acute coronary syndromes
Define Hypertension (HTN)
Sustained elevation in systemic arterial blood pressure
- Systolic > 140 mmHg
- Diastolic > 90 mmHg
Define 1º HTN
Interaction of genetic factors and environmental influences - causing neural and hormonal effects
How to diagnose 1º HTN?
Repeated high BP
Patient history
Urinalysis and blood tests
ECG
2º Hypertension
Increase in SVR or CO due to underlying disease or medication
Arteriosclerosis
Abnormal thickening and hardening (fatty-fibrous plaque) of artery walls (tunica intima) resulting in loss of elasticity
Hyperlidemia
Arteriosclerosis risk factor
Elevated levels of lipids in the blood, mainly cholesterol and triglycerides
i.e. LDL (low-density lipoprotein)
Atherosclerosis: Pathophysiology
1) endothelial dysfunction
2) lipid layer
3) leukocytes and sm cells
4) foam cell formation
5) degradation of extracellular matrix
Atherosclerosis:
Symptoms
● diminished or absent pulses ● changes in skin T° ● pain ● intermittent claudication (leg pain) ● muscle weakness ● dizziness, headaches
Aneurysm
Localised abnormal dilation or outpouching of vessel or cardiac wall
Types of Aneurysms
Fusiform
Saccula
Dissecting
Aneurysm: location
Abdominal aorta
Thoracic aorta
Femoral popliteal
Cerebral artery
Myocardial Ischaemia: Pathophysiology
Narrowing of a major coronary artery by > 50% (due to atherosclerosis)
Lactic acid
Cell death → inflammation
Acute coronary syndromes (ACS)
Obstruction of the coronary arteries with unstable angina and myocardial infarction