nurs 360 exam 2 Flashcards
stages of HIV infection
Stage 0: Acute phase or primary infection
high viral load, decrease of CD4+ count–> indicate early infection from lab testing (RNA is in the blood and they are infected during this time)
begins about a couple of weeks to a month after becoming infected and can spread to others.
Signs and symptoms: flu-like symptoms
stage 1: may present as asymptomatic bc there is still high CD4+ but decreases; based on CD4+ count
stage 2 and 3 are based on the CD4+ count
what is CD4+?
aka T Cells which are white blood cells that fight infection and play an important role in your immune system
What is viral load?
Viral load measures the amount of virus is in a given fluid
–> higher load= higher chance of transmission
How do you know when antivirals are working?
Viral load goes down
CD4+ goes up
Examples include penciclovir, peramivir, oseltamivir
How to prevent opportunisitic infections in HIV/AIDS patients?
water from treated sources, eat foods that are not raw, avoid sexual activity, keep vaccines up to date, take ART
what are the clinical manifestations of HIV/AIDS patients? What are some opportunistic infections related to HIV/AIDS?
1) Respiratory: SOB, dyspnea, cough, chest pain, and fever
☆ penumocytsitis pneumonia: pneumo vax
☆ mycobacterium avium complex
☆tuberculosis: night sweats, trouble breathing
2) GI: loss of appetite, nausea, vomiting, oral and esophageal candidiasis and chronic diarrhea
☆salmonella (avoid raw foods or contaminated water)
☆C. Difficile
☆ candidiasis (fungal infection, creamy white plaque lesions on the tongue or skin)
3) oncologic manifestations: Kaposi sarcoma (little brownish pink spots
4) neurologic: inflammation, atrophy, necrosis
☆ peripheral neuropathy
☆HIV encephalopathy: dementia complex
What is antiretroviral therapy?
AKA HAART; reduce hiv morbidity, restore and preserve immunologic function, suppresses HIV viral load, and prevent HIV transmission
What do you do if you’re started on post exposure prophylaxis (PEP):
❥ taken after a potential exposure of HIV.
❥ Has to be within 72 hours
❥ not for routine use but emergencies
❥taken for 28 days
❥HIV testing at 7 wks, 12 wks, and 6 months
medications include
- truvada and isentress (raltegravir)
- truvada and dolutegravir (tivicay)
How to prevent and treat HIV/AIDs?
1) screening: who is at risk? sexual behavior, drug usage, blood transfusion
2) educate about HIV
3) monitoring; nucleic acid tests, antigen/antibody tests, and antibody tests
What do you check for in an HIV antibody titer test?
There is no such thing.
Treatments of HIV symptoms include
Octreotide acetate, statin has been used for severe diarrhea; patho- inhibit GI motility
What type of vaccines do you avoid if you are ammunocomprimized? Give examples.
The flu vaccine is NOT a live vaccine so you can get it.
LIVE VACCINES→ Measles, mumps, rubella (MMR combined vaccine) Rotavirus. Smallpox. Chickenpox. Yellow fever.
How do you do an epinephrine injection? Where do you store an epi pen?
orange cap down, put it on the inner thigh and push for 10 seconds.
store epinephrine in a cool, dry place so dont do it in your car.
How often can you give epinephrine? Is there a limit? What meds do you give afterwards as a monitoring sign?
Give epinephrine 15 minutes in between; unlimited until they start feeling better
1) start IV epinephrine after SUBQ injections
2) then give corticosteroids and diphenhydramine afterwards
3) monitor for rebound 4-8 hours
Which drugs do you avoid during an allergy test?
antihistamine (diphenhydramine, fexofenadine) and corticosteroids (prednisone, cyrocortisone)
What happens when you stick yourself with a sharp?
go to employee health
What is a SED rate?
(erythrocyte sedimentation rate, also known as ESR) is a simple blood test that helps detect inflammation in the body.
Increased sed rate indicates inflammation.
What is CRP test?
C-reactive protein (CRP) is a protein made by the liver. CRP levels in the blood increase when there is a condition causing inflammation somewhere in the body. A CRP test measures the amount of CRP in the blood to detect inflammation due to acute conditions or to monitor the severity of disease in chronic conditions.
What is rheumatoid factor test?
A positive rheumatoid factor test result indicates that a high level of rheumatoid factor was detected in your blood. A higher level of rheumatoid factor in your blood is closely associated with autoimmune disease, particularly rheumatoid arthritis.
measures the amount of rheumatoid factor in your blood
Contraindication to diphenhydramine
drowsy, confusion, dizziness, dry mouth, nausea
anticholinergic effects
contraindication loratadine
2nd gen anti-histamine (non sedating)
headache, nervousness, edema, depression, increased appetite
What is allopurinol? What are the effects of allopurinol?
Allopurinol is used to treat gout and certain types of kidney stones. It is also used to prevent increased uric acid levels.
What are the foods associate with latex allergies>
Pineapple 🍍 Banana 🍌 Kiwi 🥝 Mangos 🥭 Passion fruit Avocados 🥑 Chestnuts 🌰
What is Cyclobenzaprine? What are the adverse effects>
Cyclobenzaprine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.
anti-cholinergic (cant see, cant, pee, cant spit, cant shit)
What is rheumatoid arthritis?
rheumatoid arthritis is an autoimmune condition where the immune system attacks the joints and attacks the synovial fluid of the joint. NO CURE.
characteristics include inflammation, autoimmunity, and degeneration
☑ inflammation of the synovial fluid, cartilage loss, exposed and pitted bones
What is DMARDS? Adverse effects?
Antimalarials: hydroxychloroquine, chloroquine
action: anti-inflammatory. inhibits lysosomal enzymes
slow acting
May be administered with NSAIDs. anticholinergic effects (visual changes0, GI upset, skin rash, headache bleaching of hair
exam for ophatmaology 6-12 months
What is Systematic lupus erythematous (lupus, SLE)?
Autoimmune chronic condition that causes inflammation (there may be flareups)
–> joints, skin, lungs, heart, kidneys, brain, and blood system can be affect.
signs and symptoms: memory loss, psychosis, memory loss
lupus can affect the hair and skin: skin rashes (malar discoid), alopecia
heart: murmur, pericarditis
kidneys: retain fluid, renal failure, lupus nephritis
What medications do you use for rheumatoid arthritis for the early stages
Methotrexate
Patient education about lupus
labs:
☑ anti-body labs; positive ANA (the body created against the nuclei of the cells)
☑anti-dsDNA (found in some pts with lupus and is not typcially presents in pts who dont have lupus
☑ CBC (white blood cells, anemia), metabolic panel (renal function)
medications:
☑steroids (prednisone, prednisolone)–> decreases inflammation quickly
☑ NSAIDs
☑anti-malarial : hydrocychlorquine: decreases antibodies attacking the body (does not see immediate results, tae with food must check eyes regularly, no smoking)
☑ immunosuppressants: azathioprine or mycophenolate mofetil; suppresses immune system
- steroid sparking, increases risk for infection and certain cancer
-educated about preventing infection and monitoring self for infection, NO LIVE VACCINEs