NUR 326 exam 1b Flashcards
pneumocystis carini pneumonia
related to immune suppression (hiv, transplant)
yeast-like fungus
mycoplasma
walking pneumonia
mild pna (persistent cough, headache, earache)
organism is between virus and bacteria
legionella
gram negative
spreads via water systems (air conditioners, mists on produce, hot tubs)
aspergillus
fungal pna
walls of old buildings, reconstruction, stored grain, dead leaves, compost
affects lung tissue
pcv13
vaccine preventing pneumococcal pneumonia
ppsv23
vaccine preventing additional types of pna bacteria
staphylococcus aureus
most common cause of gram + HAP
usually mrsa
usually enters through blood stream and travels to lungs
streptococcus pneumoniae
most common cause of CAP
pneumococcal pneumonia
sputum usually brown or rusty
common gram - pna organisms
pseudomonas, aceinetobacter
macrocytic - normochromic
B12 and folate deficiency
microcytic - hypochromic
iron deficiency
normocytic - normochromic anemia
blood loss, sickle cell, aplastic
iron deficiency anemia lab
mcv decreased
B12 or folate deficiency anemia lab value
mcv increased
iron deficiency symptoms
mouth changes
spoon nails
pica
b12 deficiency anemia symptoms
neuropathy
ataxia (difficulty walking)
glossitis
dementia/psychosis
hemolytic anemia symptoms
low hemoglobin
increased reticulocyte count (immature rbcs)
mild jaundice
sickle cell anemia symptoms
swelling of hands and feet (from occluded blood vessels)
painful episodes
sickle cell crisis triggers
dehydration
stress
high altitudes
fever
extreme temperatures
sickle cell treatment
hydroxyurea (antimetabolite drug)
thalassemia symptoms
delayed growth
fatigue
dyspnea
hepatomegaly
splenomegaly
bone deformities
jaundice
diphenhydramine class
sedating antihistamine
diphenhydramine indications
allergic reactions (mild, anaphylaxis)
motion sickness
diphenhydramine se
dry up body (constipation, dry mouth)
drowsiness / dizziness
diphenhydramine nursing considerations
avoid driving or operating machinery
non-sedating antihistamines
loratadine
fexofenadine
cetirizine
non-sedating antihistamines indication
allergic rhinitis
chronic idiopathic urticaria
antihistamine moa
bind to HI receptors and block histamine release
mild cholinergic
sympathomimetics
phenylephrine
pseudoephedrine
sympathomimetics moa
mimic sns
activate a1-adrenergic receptors
constricts nasal blood vessels
sympathomimetics indications
reduce nasal congestion
sympathomimetics se
cns stimulation (agitation, insomnia, anxiety, tachycardia)
sympathomimetics time limit
take for no more than 4 days (rebound congestion)
pseudoephedrine
potential for abuse
antitussives
dextromethorphan
codeine
benzoatate
antitussive moa
directly suppresses cough reflex in the brain
antitussive indications
chronic or acute cough
antitussive se
cns depression
antitussives nursing considerations
potential for abuse
guaifenesin class
expectorant
guaifenesin moa
reduces surface tension of secretions
guaifenesin indication
decrease mucus in colds or bronchitis
guaifenesin se
mild gi distress
guaifenesin nursing considerations
encourage hydration for secretion thinning
acetylcysteine class
mycolytics
acetylcysteine moa
decreases mucus viscosity
acetylcysteine indications
bronchopulmonary disease
cystic fibrosis
acetylcysteine se
bronchospasm
short acting beta-adrenergic agonists
albuterol
levalbuterol
beta-adrenergic agonists moa
mimic action of sns
stimulate beta-2 adrenergic receptors to relax and dilate airways
albuterol indication
rescue
prevention of exercise induced asthma
beta-adrenergic agonists contraindication
uncontrolled HTN
cardiac dysrhythmia
high stroke risk
beta-adrenergic agonists se
hypertension / hypotension
insomnia / restlessness
cardiac stimulation
beta-adrenergic agonists nursing considerations
diminish effects of beta blockers
increase blood sugar
why inhalers
minimize systemic effects
albuterol time dosed
inhaled every 4-6 hours
salmetrol time dosed
inhaled every 12 hours
salmetrol always given with
inhaled corticosteroid
salmetrol indication
prevention
copd bronchospasm
long acting beta-adrenergic agonist
salmetrol
formoterol
ipratroprium class
anticholinergic
ipratroprium moa
blocks action of acetylcholine
causes bronchodilation
ipratroprium indication
copd prophylaxis
ipratroprium se
dry as a bone
hot as a hare
blind as a bat
red as a beet
mad as a hatter
xanthine derivatives
theophylline
aminophylline
xanthine derivatives moa
inhibits phosphodiesterase
increase cAMP
stimulates cns
xanthine derivatives indication
2nd line treatment to prevent copd exacerbation
xanthine derivatives se
toxicity
n/v, lack of appetite
lots of contraindications
xanthine derivatives nursing considerations
narrow therapeutic index (monitor)
avoid caffeine
lots of drug interactions
leukotriene receptor agonist
montelukast
zafirlukast
LTRA moa
prevent leukotrienes from attaching to immune cells in the lungs
prevents inflammation
LTRA indication
prophylaxis and treatment of non emergent asthma
LTRA se
headache
n/d
dizziness
inhaled corticosteroids
beclomethasone diproprionate
budesonide
fluticasone
inhaled corticosteroids moa
reduce inflammation
enhance beta agonist activity
inhaled corticosteroids indication
prevention of copd
inhaled corticosteroids se
pharyngeal irritation (rinse mouth)
inhaled corticosteroids nursing consideration
take bronchodilator 1st
cromolyn class
mast cell stabilizer
cromolyn moa
stabilize mast cell membranes
prevent release of bronchorestrictive inflammation
cromolyn indicaiton
prevention of asthma attack (15 min before known trigger)
omalizumab class
monoclonal antibody anti asthmatic
omalizumab moa
limits release of mediators of allergic response
omalizumab se
anaphylaxis (monitor closely)
roflumilast class
pde-4 inhibitor
roflumilast moa
binds to pde-4 in lungs
lows inflammation
roflumilast indication
prevents copd exacerbation
roflumilast se
n/v/d
spasms/tremors
isoniazid moa
disrupts bacterial cell wall synthesis
isoniazid indication
active tb
isoniazid se
peripheral neuropathy
hepatotoxicity
vision changes
hyperglycemia
isoniazid bbw
risk of hepatitis
isoniazid nursing considerations
monitor liver enzymes
avoid antacids
rifampin moa
attack hydrocarbon ring structure
inhibiting protein synthesis
rifampin indication
myobacterial infections
rifampin se
hepatitis
hematologic disorders
re-brown body fluids
rifampin nursing considerations
lots of drug interactions
tell HCP if on this
ethambutol moa
suppress rna and protein synthesis
ethambutol se
visual changes
ethambutol age
not for children under 13
pyrazinamide moa
unknown
pyrazinamide se
hepatotoxicity
hyperuricemia
pyrazinamide contraindications
hepatic disease
acute gout
pregnancy
streptomycin moa
interfere with normal protein synthesis
streptomycin se
ototoxicity
nephrotoxicity
blood dyscraias
streptomycin nursing considerations
can increase bleeding with anticoagulants
oral iron supplement
ferrous sulfate
parenteral iron
iron dextran
iron therapy indications
iron deficient anemia
blood loss
iron dextran bbw
allergic reaction (have epi ready)
iron therapy se
gi upset
metallic taste
stain teeth
overdose in children
dark stool
iron therapy drug interactions
decreased absorption with antacids
increased absorption with vitamin c
iron therapy nursing consideration
best absorbed on empty stomach
deferoxamine
treats iron toxicity
cyanocobalamin moa
b12 replacement
cyanocobalamin indication
b12 anemia
epoetin alfa class
erythropoietin stimulating agent
epoetin alfa moa
stimulates erythropoietin
increases hemoglobin and reticulocyte counts
epoetin alfa indication
anemia with chronic kidney disease
epoetin alfa se
polycythemia (hypertension / CV event)
cancer progression
epoetin alfa contraindications
uncontrolled htn
epoetin alfa bbw
cv risk (stroke, mi)
epoetin alfa parameters
ONLY if hemoglobin <10 OR on dialysis
monitor levels weekly so not above 11