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ABSN > NUR 326 exam 1a > Flashcards

NUR 326 exam 1a Flashcards

1
Q

beta lactam antibiotics

A

sulfabactam
clavulanic acid
tazobactam
avibactam

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2
Q

beta lactam moa

A

prevents action of beta lactamase
allows antibiotic to do work

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3
Q

beta lactam indication

A

given with other antibiotics that have a beta lactam ring

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4
Q

penicillin general moa

A

inhibits cell wall synthesis and weakens cells wall

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5
Q

penicillin general indication

A

growing and dividing bacteria

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6
Q

penicillin se

A

urticaria
prurtis
angioedema

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7
Q

penicillin nursing considerations

A

lots of drug interactions

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8
Q

natural penicillins

A

PCN G
PCN V

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9
Q

natural penicillins indications

A

least toxic
common for STIs

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10
Q

penicillinase-resistant penicillins

A

nafcillin

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11
Q

nafcillin moa

A

resistant to penicillinase

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12
Q

nafcillin route

A

iv only

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13
Q

aminopenicillins

A

amoxicillin
ampicillin

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14
Q

aminopenicillin se

A

diarrhea
rash

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15
Q

aminopenicillin nursing considerations

A

commonly combined with beta lactam

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16
Q

extended spectrum penicillin

A

piperacillin

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17
Q

piperaillin indications

A

pseudomonas infection

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18
Q

piperacillin se

A

effects platelet and renal function

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19
Q

piperacillin nursing considerations

A

always given with a beta lactam

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20
Q

cephalosporins moa

A

inhibit cell wall synthesis through penicillin-binding protein
activates autolysis

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21
Q

cephalosporins indications

A

increased ability to penetrate csf

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22
Q

cephalosporins se

A

rash
gi upset
itching, redness, edema

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23
Q

cephalosporins nursing considerations

A

avoid if patient is allergic to penicillins
poor oral absorption

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24
Q

1st gen cephalosporin

A

cefazolin
cephalexin

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25
Q

cefazolin, cephalexin indication

A

staph and strep infections

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26
Q

cefazolin indication

A

iv only for surgical prophylaxis

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27
Q

2nd gen cephalosporins

A

cefuroxime
cefotetan

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28
Q

cefuroxime, cefotetan indication

A

aerobic bacteria

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29
Q

3rd gen cephalosporins

A

ceftriaxone
ceftazidime
cefotaxine

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30
Q

3rd gen ceph indication

A

potent for gram -

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31
Q

ceftiaxone

A

long acting
crosses bbb
not for liver failure patients

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32
Q

ceftazidime indication

A

pseudomonas

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33
Q

4th gen cephalosporins

A

cefapime

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34
Q

cefapime moa

A

broad spectrum
crosses bbb

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35
Q

ceftaroline indication

A

mrsa, mssa
vrsa, visa
complicated infections

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36
Q

5th gen cephalosporins

A

ceftaroline

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37
Q

carbapenems moa

A

cell wall inhibition
broadest spectrum

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38
Q

carbapenems indication

A

last resort

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39
Q

carbapenems se

A

seizures

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40
Q

carbapenems nursing considerations

A

iv infused over at least 60 min

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41
Q

imipenem, cliastin moa

A

very beta lactamase resistant

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42
Q

imipenem, cliastin indication

A

complicated infection
can penetrate bbb

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43
Q

cliastin purpose

A

stops breakdown of imipenem in kidneys

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44
Q

meropenem se

A

rash
diarrhea

45
Q

glycopeptide antibiotic

A

vancomycin

46
Q

vancomycin moa

A

DIRECT and immediate inhibition of cell wall

47
Q

vancomycin indication

A

mrsa
pcn-resistant pseudomonas

48
Q

vancomycin oral indication

A

cdiff
pseudomembranous colitis

49
Q

vancomycin se

A

ototoxicity
thrombocytopenia
nephrotoxic
redman’s syndrome

50
Q

vancomycin nursing considerations

A

not for cns infection
peak and tough monitored

51
Q

aminoglycosides moa

A

inhibit or alter protein (or dna) synthesis

52
Q

aminoglycosides

A

gentamycin
amikacin
tobramycin

53
Q

aminoglycosides se

A

nephrotoxic
ototoxic

54
Q

gentamycin se

A

not given with paralytics
cns depression
cochlear damage

55
Q

aminoglycosides nursing considerations

A

peak and trough monitoring

56
Q

lincosamides

A

clindamycin

57
Q

clindamycin moa

A

bactericidal or bacteriostatic depending on the concentration

58
Q

clindamycin se

A

deadly pseudomembranous colitis

59
Q

clindamycin nursing considerations

A

very toxic (monitor levels)

60
Q

macrolides

A

erythromycin
azithromycin

61
Q

macrolides indications

A

normal infections
legionnaires, listeria, mycoplasma pneumonia

62
Q

macrolides se

A

intense gi distress

63
Q

erythromycin indication

A

increase gastric motility in diabetic gastroparesis

64
Q

erythromycin nursing considerations

A

not on empty stomach

65
Q

azithromycin different from erythromycin

A

better coverage
good tissue penetration
less gi upset

66
Q

azithromycin nursing consideration

A

take without food to increase absorption

67
Q

tetracyclines

A

tetracycline
doxycycline
minocycline

68
Q

tetracyclines indication

A

broad spectrum (rickettsia, chlamydia, Lyme disease, cholera)

69
Q

doxycycline indication

A

STIs, acne

70
Q

minocycline indication

A

meningitis
rheumatoid arthritis

71
Q

tetracyclines se

A

tooth discoloration
enamel degradation

72
Q

tetracyclines nursing considerations

A

not for pregnant or nursing moms

73
Q

fluoroquinolone

A

ciprofloxacin
levofloxacin

74
Q

fluoroquinolone Moa

A

interfere with dna gyrase and topoisomerase

75
Q

ciprofloxacin indication

A

normal infection
anthrax

76
Q

ciprofloxacin se

A

arthopathy

77
Q

ciprofloxacin age range

78
Q

levofloxacin indication

A

atypical respiratory infection

79
Q

levofloxacin se

A

cns disorder
kidney failure
photosensitivity
prolonged qt interval

80
Q

levofloxacin nursing consideration

A

100% bioavalibility po

81
Q

sulfonamides

A

sulfamethoxale + trimethoprim
BACTRIM

82
Q

bactrim moa

A

prevents synthesis of folic acid for dna synthesis

83
Q

bactrim indications

A

uncomplicated utis
respiratory infection
samonella, shigellosis, hiv

84
Q

bactrim se

A

“sulfa” allergies
photosensitivity

85
Q

metronidazole class

A

antiprotozoal and antibacterial

86
Q

metronidazole moa

A

inhibits dna synthesis

87
Q

metronidazole indication

A

crohns disease
antibiotic associated diarrhea

88
Q

metronidazole se

A

n/v
xerostomia
vaginal candidiasis

89
Q

metronidazole nursing consideration

A

do NOT take with alcohol

90
Q

antivirals

A

acyclovir
oseltamivir
ganciclovir

91
Q

acyclovir moa

A
  1. interfers with rna/dna
  2. prevents viruses from entering cells
  3. stimulates immune system to kill viruses
92
Q

acyclovir indication

A

herpes (oral, genital, chickenpox)
reduces severity but does not cure

93
Q

acyclovir se

A

gi upset
renal impairment
idiopathic thrombocytopenia
tissue necrosis if iv not patent

94
Q

oseltamivir moa

A

inhibit neuraminidase to stop viral replication

95
Q

oseltamivir indication

A

flu prophylaxis or within 48 hours of symptoms
elderly or immunocompromised

96
Q

oseltamivir se

A

n/v
seizures
renal impairment

97
Q

genciclovir moa

A

inhibits viral dna polymerases
stops virus from replicating

98
Q

ganciclovir indication

A

cytomegalovirus (immunocompromised, controls but does not cure)

99
Q

ganciclovir bbw

A

hematological toxicity
fertility impairment
fetal toxicity
carcinogenesis

100
Q

dont give ganciclovir with…

A

imipenem (seizure potential)

101
Q

antiretroviral therapy moa

A
  1. block viral entry
  2. inhibit NRTIs
    **stop hiv from multiplying
102
Q

ART cocktail

A

2 nucleoside meds with one from another class

103
Q

goal of ART

A

decrease viral load to undetectable level

104
Q

how we monitor hiv progression

A

cd4 count and viral load

105
Q

nucleoside reverse transcriptase inhibitors se

A

peripheral neuropathy
pancreatitis

106
Q

NRTIs bbw

A

lactic acid syndrome

107
Q

pre exposure prophylaxis

A

use of meds if partner has hiv

ABSN (7 decks)

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