NUR 112 Exam 2 Drugs Flashcards

Anemia, Thyroid & Diabetes drugs

1
Q

Plicamycin - What does it Tx? How does it work?

A

Hyperparathyroidism

Lowers serum calcium

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2
Q

Alendronate - Pamidronate
?Category
What does it Tx? How does it work?
Route of admin for each?

A
Biphosphonates
Tx for Hyper PTH
Inhibits release of calcium from bone
Alendronate - IV
Pamidronate - PO
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3
Q

Propanolol / Atenolol
?Category
What does it Tx? How does it work?

A

Beta adrenergic blockers
Tx HYPER thyroidism
symptomatic relief

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4
Q

Methimazole
?Category
What does it Tx? How does it work?
Dose freq?

A

Thiomide
Tx HYPER thyroidism
inhibits synthesis of thyroid hormones
Q day

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5
Q

Iodine

What does it Tx? How does it work?

A

Tx HYPER thyroidism

inhibits synthesis & blocks release of T3/T4

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6
Q

repaglinide - nateglinide
?Category
What does it Tx? How does it work?
Side effects?

A

Meglitinides
RAPID stim release of insulin from pancreas
Hypoglycemia & weight gain

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7
Q

Pramlintide
Category
What does it Tx? How does it work?
Side effects?

A
Amylin Analog - SC**** (can take w/ insulin)
Tx - DM insulin deficiency
Inc satiety (dec. caloric intake)
dec gastric emptying
reduces glucagon secretion after meals
Hypoglycemia
dec. appetite/headache
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8
Q

propythiouracil
?Category
What does it Tx? How does it work?
Dose freq?

A

Thiamide - anti thyroid
inhibits synthesis thyroid hormones
take TID

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9
Q

Furosemide

What does it Tx? How does it work?

A

hypercalcemia as a result of hyperparathyroidism

diuretic

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10
Q

Iodine 131

What does it Tx? How does it work?

A

hyperthyroidism

destroys tissue that makes T3/T4

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11
Q

Lithium

What does it Tx? How does it work?

A

hyperthyroidism

Blocks hormones resulting in hypothyroidism

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12
Q

filgrastrim - pegfilgrastrim

What does it Tx? How does it work?

A

Neutropenia

stim bands to mature, & activates segments

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13
Q

Exenatide - liraglutide
Category
What does it Tx? How does it work?
Side effects?

A
Incretin mimic
DM insulin deficiency
stimulates release of insulin
Inc satiety 
dec gastric emptying
reduces glucagon secretion 
Hypoglycemia
NVD, hypoglycemia, headache
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14
Q

Oprelvekin
What does it Tx? How does it work?
Route?

A

thrombocytopenia
Stim Bone Marrow to produce megakaryocytes & platelets
SC

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15
Q

sitagliptin - saxagliptin
Category
What does it Tx? How does it work?
Side effects?

A

Dipeptidyl peptidase - 4 inhibitor
DM insulin deficiency
release of insulin - enhances incretin system
URTI, sore throat, headache, UTI, diarrhea

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16
Q

Procrit
What does it Tx?
Routes?

A

aplastic anemia caused by Chemo, renal failure or AIDS Tx

SC or IV

17
Q

Epogen
What does it Tx?
Routes?

A

aplastic anemia caused by Chemo, renal failure or AIDS Tx

SC or IV

18
Q
What do the following drugs all Tx? (1 condition)
Calcium chloride
calcium gluconate
Magnesium sulphate
Calcium/Vit D supplements
A

hypoparathyroidism

19
Q
pioglitazone - rosiglitazone
Category
What does it Tx? How does it work?
Side effects?
DO NOT USE in pt. with \_\_\_\_\_\_\_\_\_\_\_\_\_\_?
A
Thiazolidinediones (insulin sensitizers)
DM insulin deficiency
Inc glucose uptake in muscle
dec endogenous glucose production
weight gain, Inc risk MI/CVA
\_\_\_\_\_\_\_\_\_ HF!
20
Q

Levothyroxine
What does it Tx?
Time of day to take?

A

hypothroidism

AM empty stomach

21
Q
ascarbose - miglitol
Category
What does it Tx? How does it work?
Side effects?
NB\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
A
alpha glucosidase inhibitor
DM insulin deficiency
delays absorption of glucose from GI tract
gas, abdominal pain, diarrhea
NB\_\_\_ take with 1st bite of each meal
22
Q
metformin
Category
What does it Tx? How does it work?
Side effects?
Do not use in pt. with a, b, c, d.
NB \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
A
biguanide
Pre diabetes & DM insulin deficiency
dec rate liver glucose production
helps glucose enter tissues esp. muscles
diarrhea, lactic acidosis
a. kidney disease
b. liver disease
c. HF
d. Hx X.S. alcohol use
NB \_\_\_ HOLD 1-2 days B4 IV contrast and 48 hours after (to protect kidneys)
23
Q
Humalog, novolog, apidra
Type:
Onset O:
Peak P:
Duration D:
A

Type: Rapid acting
Onset O: 15 min
Peak P: 60-90 min
Duration D: 3-4 hr

24
Q
Humulin N, Novolin N, ReliOn N
Type:
Onset O:
Peak P:
Duration D:
A

Type: Intermediate
Onset O: 2-4 hrs
Peak P: 4-10 hr
Duration D: 10-16 hr

25
Q

glipizide - glyburide - glimepiride
Category
What does it Tx? How does it work?
Side effects?

A
sulfonylureas
DM insulin deficiency
Stim release of insulin
enhance cell sensitivity to  insulin
dec. glycogenosis & gluconeogensis
hypoglycemia, weight gain
26
Q
lantus, Levemir
Type:
Onset O:
Peak P:
Duration D:
A

Type: Long acting
Onset O: 1-2 hr
Peak P: 0
Duration D: 24 hrs +

27
Q
Humulin R, Novolin R, ReliOn R
Type:
Onset O:
Peak P:
Duration D:
A

Type: Regular - short acting
Onset O: 30 min - 1 hr
Peak P:2-3 hr
Duration D: 3-6 hr