NUR 112 Exam 2 Drugs Flashcards
Anemia, Thyroid & Diabetes drugs
Plicamycin - What does it Tx? How does it work?
Hyperparathyroidism
Lowers serum calcium
Alendronate - Pamidronate
?Category
What does it Tx? How does it work?
Route of admin for each?
Biphosphonates Tx for Hyper PTH Inhibits release of calcium from bone Alendronate - IV Pamidronate - PO
Propanolol / Atenolol
?Category
What does it Tx? How does it work?
Beta adrenergic blockers
Tx HYPER thyroidism
symptomatic relief
Methimazole
?Category
What does it Tx? How does it work?
Dose freq?
Thiomide
Tx HYPER thyroidism
inhibits synthesis of thyroid hormones
Q day
Iodine
What does it Tx? How does it work?
Tx HYPER thyroidism
inhibits synthesis & blocks release of T3/T4
repaglinide - nateglinide
?Category
What does it Tx? How does it work?
Side effects?
Meglitinides
RAPID stim release of insulin from pancreas
Hypoglycemia & weight gain
Pramlintide
Category
What does it Tx? How does it work?
Side effects?
Amylin Analog - SC**** (can take w/ insulin) Tx - DM insulin deficiency Inc satiety (dec. caloric intake) dec gastric emptying reduces glucagon secretion after meals Hypoglycemia dec. appetite/headache
propythiouracil
?Category
What does it Tx? How does it work?
Dose freq?
Thiamide - anti thyroid
inhibits synthesis thyroid hormones
take TID
Furosemide
What does it Tx? How does it work?
hypercalcemia as a result of hyperparathyroidism
diuretic
Iodine 131
What does it Tx? How does it work?
hyperthyroidism
destroys tissue that makes T3/T4
Lithium
What does it Tx? How does it work?
hyperthyroidism
Blocks hormones resulting in hypothyroidism
filgrastrim - pegfilgrastrim
What does it Tx? How does it work?
Neutropenia
stim bands to mature, & activates segments
Exenatide - liraglutide
Category
What does it Tx? How does it work?
Side effects?
Incretin mimic DM insulin deficiency stimulates release of insulin Inc satiety dec gastric emptying reduces glucagon secretion Hypoglycemia NVD, hypoglycemia, headache
Oprelvekin
What does it Tx? How does it work?
Route?
thrombocytopenia
Stim Bone Marrow to produce megakaryocytes & platelets
SC
sitagliptin - saxagliptin
Category
What does it Tx? How does it work?
Side effects?
Dipeptidyl peptidase - 4 inhibitor
DM insulin deficiency
release of insulin - enhances incretin system
URTI, sore throat, headache, UTI, diarrhea
Procrit
What does it Tx?
Routes?
aplastic anemia caused by Chemo, renal failure or AIDS Tx
SC or IV
Epogen
What does it Tx?
Routes?
aplastic anemia caused by Chemo, renal failure or AIDS Tx
SC or IV
What do the following drugs all Tx? (1 condition) Calcium chloride calcium gluconate Magnesium sulphate Calcium/Vit D supplements
hypoparathyroidism
pioglitazone - rosiglitazone Category What does it Tx? How does it work? Side effects? DO NOT USE in pt. with \_\_\_\_\_\_\_\_\_\_\_\_\_\_?
Thiazolidinediones (insulin sensitizers) DM insulin deficiency Inc glucose uptake in muscle dec endogenous glucose production weight gain, Inc risk MI/CVA \_\_\_\_\_\_\_\_\_ HF!
Levothyroxine
What does it Tx?
Time of day to take?
hypothroidism
AM empty stomach
ascarbose - miglitol Category What does it Tx? How does it work? Side effects? NB\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
alpha glucosidase inhibitor DM insulin deficiency delays absorption of glucose from GI tract gas, abdominal pain, diarrhea NB\_\_\_ take with 1st bite of each meal
metformin Category What does it Tx? How does it work? Side effects? Do not use in pt. with a, b, c, d. NB \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
biguanide Pre diabetes & DM insulin deficiency dec rate liver glucose production helps glucose enter tissues esp. muscles diarrhea, lactic acidosis a. kidney disease b. liver disease c. HF d. Hx X.S. alcohol use NB \_\_\_ HOLD 1-2 days B4 IV contrast and 48 hours after (to protect kidneys)
Humalog, novolog, apidra Type: Onset O: Peak P: Duration D:
Type: Rapid acting
Onset O: 15 min
Peak P: 60-90 min
Duration D: 3-4 hr
Humulin N, Novolin N, ReliOn N Type: Onset O: Peak P: Duration D:
Type: Intermediate
Onset O: 2-4 hrs
Peak P: 4-10 hr
Duration D: 10-16 hr
