NUR 112 Exam 1 Electrolytes K+ Flashcards
K+ major cation found in ECF or ICF?
ICF
Name cation needed for Na+ - K+ pump to work properly
Mg 2+
In addition to neuromuscular and cardiac function list 3 things that K+ does in the body
- regulates intracellular osmolality
- promotes cell growth
- Reg acid-base balance
What organ excretes the majority of K+?
kidney
K+ has an inverse relationship with which other cation? (1 is retained the other is excreted and vice versa)
Na+
Will low blood volume cause K+ to be conserved or lost?
lost
Low BV = aldosterone production = inc. in reabsorption of Na+ = loss of K+
List 2/3 things (drugs/situations) that cause K+ to shift from ECF to ICF
- insulin
- beta adrenergic stimulation (stimulates Na+ K+ ATP pump)
- alkalosis (K+ exchanges with H+)
List 2/3 things (drugs/situations) that cause K+ to shift from ICF to ECF
- cell trauma (burns/crush injury/tumor lysis)
- exercise
- acidosis
list 3 major causes of hyperkalemia
- massive intake (salt substitute, K+ in drugs, IV fluid, hemolyzed RBC)
- impaired excretion by kidneys.
- shift of K+ from ICF to ECF
list causes of impaired excretion of K+ by kidneys (4)
- renal disease
- K+ sparing diuretics
- ACE inhibitors
- adrenal insufficiency - not enough aldosterone = Na + excretion = K + retention
At cellular level what does inc. in ECF K+ do?
increases cellular excitability
s/s hyperkalemia in skeletal muscles
leg cramps
weakness
paralysis
s/s hyperkalemia in smooth muscles
hyperactivity leading to: abdominal cramps
diarrhea
s/s hyperkalemia in cardiac muscle
cardiac conduction disturbances: cardiac depolarization is decreased cardiac repolarization occurs more quickly QRS complex widens T waves Tall and peaked v. fib v. standstill
general s/s hyperkalemia (4)
irritability
anxiety
parasthesias
irregular pulse
List 5 main Tx for hyperkalemia
- eliminate oral/parenteral K+ intake
- eliminate K+ or dilute.
- shift K+ from ECF to ICF
- reverse (reduce) membrane excitability
- hemodialysis (if pt. has renal failure)
3 ways to eliminate/dilute K+ from/in body
- diuretics
- kayexalate (resin binds K+ in exchange for Na+ - then excreted in feces)
- inc. fluids (inc. renal elimination)
What is used to force K+ from ECF to ICF?
Insulin & glucose
What is calcium gluconate used for in hyperkalemia?
to reverse (reduce) membrance excitability. Given in addition to diuretics, kayexalate, and insulin if pt. is experiencing dysrhythmias
If pt. has renal failure and hyperkalemia what is Tx of choice?
hemodialysis