NUR 112 Exam 1 Electrolytes K+ Flashcards
K+ major cation found in ECF or ICF?
ICF
Name cation needed for Na+ - K+ pump to work properly
Mg 2+
In addition to neuromuscular and cardiac function list 3 things that K+ does in the body
- regulates intracellular osmolality
- promotes cell growth
- Reg acid-base balance
What organ excretes the majority of K+?
kidney
K+ has an inverse relationship with which other cation? (1 is retained the other is excreted and vice versa)
Na+
Will low blood volume cause K+ to be conserved or lost?
lost
Low BV = aldosterone production = inc. in reabsorption of Na+ = loss of K+
List 2/3 things (drugs/situations) that cause K+ to shift from ECF to ICF
- insulin
- beta adrenergic stimulation (stimulates Na+ K+ ATP pump)
- alkalosis (K+ exchanges with H+)
List 2/3 things (drugs/situations) that cause K+ to shift from ICF to ECF
- cell trauma (burns/crush injury/tumor lysis)
- exercise
- acidosis
list 3 major causes of hyperkalemia
- massive intake (salt substitute, K+ in drugs, IV fluid, hemolyzed RBC)
- impaired excretion by kidneys.
- shift of K+ from ICF to ECF
list causes of impaired excretion of K+ by kidneys (4)
- renal disease
- K+ sparing diuretics
- ACE inhibitors
- adrenal insufficiency - not enough aldosterone = Na + excretion = K + retention
At cellular level what does inc. in ECF K+ do?
increases cellular excitability
s/s hyperkalemia in skeletal muscles
leg cramps
weakness
paralysis
s/s hyperkalemia in smooth muscles
hyperactivity leading to: abdominal cramps
diarrhea
s/s hyperkalemia in cardiac muscle
cardiac conduction disturbances: cardiac depolarization is decreased cardiac repolarization occurs more quickly QRS complex widens T waves Tall and peaked v. fib v. standstill
general s/s hyperkalemia (4)
irritability
anxiety
parasthesias
irregular pulse