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FRCA > Numberwang > Flashcards

Numberwang Flashcards

1
Q

MAC in 100% O2

  • Des
  • Sevo
  • Iso
  • Xe
  • N2O
A 
Des 6.6
Sevo 2.0 
Iso 1.1 
Xe 71
N2O 105
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2
Q

B:G (speed of onset/offset)

  • Des
  • Sevo
  • Iso
  • Xe
  • N2O
A 
Des 0.45
Sevo 0.7
Iso 1.4 
Xe 0.12 
N2O 0.47
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3
Q

O:G (potency)

  • Des
  • Sevo
  • Iso
  • Xe
  • N2O
A 
Des 29
Sevo 80
Iso 98
Xe 1.9
N2O 1.4
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4
Q

Neuraxial blockade levels

  • LSCS
  • MROP
  • Labour
  • EVAR
  • TURP
A 
LSCS: T4 cold, T6 pinprick, down to S3
MROP: T6
Labour: T10 (pain is T10-L1 1st stage, S2-4 2nd stage)
Cervical cerclage: T10 
EVAR: T10 
TURP: T10
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5
Q

Elimination t1/2 (m)

  • Morphine
  • Fentanyl
  • Alfentanil
  • Remi
A

Morphine 170
Fentanyl 190
Alfentanil 100
Remi 10

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6
Q

Clearance (ml/kg/min)

  • Morphine
  • Fentanyl
  • Alfentanil
  • Remi
  • Thio
  • Pethidine
A 
Morphine 16
Fentanyl 13 
Alfentanil 6
Remi 40 
Thio 3
Pethidine 10
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7
Q

Vd (L/kg)

  • Morphine
  • Fentanyl
  • Propofol
  • Pethidine
  • Tramadol
  • Alfentanil
  • Remi
  • Thio
A 
Morphine 4 
Fentanyl 4 
Propofol 4 
Pethidine 4 
Tramadol 4 
Alfentanil 0.6 
Remi 0.3 
Thio 2
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8
Q

Plasma protein binding (%)

  • Morphine
  • Fentanyl
  • Alfentanil
  • Remi
  • Propofol
  • Thio
  • Pethidine
  • Tramadol
  • Lidocaine
  • Bupivacaine
A 
Morphine 35
Fentanyl 83
Alfentanil 90
Remi 70
Propofol 98 
Thio 85 
Pethidine 40 
Tramadol 20 
Lidocaine 65
Bupivacaine 95
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9
Q

pKa

  • Aspirin
  • Midazolam, alfentanil
  • Remi
  • Thio, diamorphine
  • Lidocaine
  • Morphine
  • Bupivacaine, ropivacaine
  • Fentanyl
  • Pethidine
  • Propofol
A 
Aspirin 3.0 
Midazolam, alfentanil 6.5 
Remi 7.1 
Thio, diamorphine 7.6 
Lidocaine 7.9
Morphine 8.0 
Bupivacaine, ropivacaine 8.1 
Fentanyl 8.4 
Pethidine 8.7 
Propofol 11.0
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10
Q

Unionised fraction at pH 7.4 (%)

  • Morphine
  • Fentanyl
  • Alfentanil
  • Remi
A

Morphine 23
Fentanyl 9
Alfentanil 89
Remi 68

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11
Q

Relative lipid solubility

  • Morphine
  • Fentanyl
  • Alfentanil
  • Remi
  • Pethidine
  • Diamorphine
A 
Morphine 1
Fentanyl 600 
Alfentanil 90 
Remi 20 
Pethidine 30 
Diamorphine 200
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12
Q

Cobb angle

A

10 degrees minimum for diagnosis of scoliosis
Surgery when >45-50 degrees
>60 = significant respiratory compromise

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13
Q

COSHH max agent concs (ppm)

  • Halothane
  • N2O
  • Enflurane/isoflurane
A

Halothane 10
N2O 100
Enflurane/isoflurane 50

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14
Q

BP (degrees C)

  • Des
  • Sevo
  • Iso
  • Xe
  • N2O
A 
Des 23
Sevo 58.5
Iso 48.5
Xe -108 
N2O -89
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15
Q

SVP at 20C (kPa)

  • Des
  • Sevo
  • Iso
A

Des 88
Sevo 21
Iso 33

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16
Q 
Steroid equivalence (mg) 
Pred, hydrocort, methylpred, dex
A

Pred 5
Hydrocort 20
Methylpred 4
Dex 0.75

17
Q

Oral opioid equivalence (ratios)
Morphine, oxycodone, tramadol, codeine
Buprenorphine and fentanyl patches

A

Morphine 1
Oxycodone 2
Tramadol 0.15
Codeine 0.1

Transdermal:
Buprenorphine 5mcg/h patch = 12mg Oramorph
Fentanyl 50mcg/h patch = 180mg Oramorph

18
Q

Umbilical vessel SpO2

A

Vein 70%

Artery 45%

19
Q

Incidence of inherited diseases

  • Down’s syndrome
  • CF
  • MD
  • CHD
  • HCM
  • SCD
  • Bicuspid AV
  • Autism
  • RA
  • MH
A

Down’s 1 in 1000 live births
CF 1 in 2500 live births (1 in 25 carrier allele)
MD 1 in 8000 prevalence
CHD 1% live births
HCM 1 in 500 prevalence (25% cases obstructive)
SCD 1 in 2000 live births
Bicuspid aortic valve 0.5-2.5%
Autism 1%
RA 1-2%
MH 1 in 5000-10,000 susceptible; 1 in 40,000-100,000 GAs

20
Q

Prevalence of acquired diseases

  • Diabetes
  • Post tonsillectomy bleed
  • Asthma
  • COPD
  • IHD
  • HTN
  • Obesity
  • AF
  • PD
  • OSA
  • Dementia
  • AS and aortic sclerosis
  • GBS
  • MG
  • Phaeo
  • Latex allergy
  • Penicillin allergy
  • Anaphylaxis
  • Alcohol misuse
  • PONV
A

Diabetes 9% (90% type 2)
Post tonsillectomy bleed 0.5-2%
Asthma 12% (>1400 deaths/y)
COPD 2% (diagnosed; much more undiagnosed)
IHD 4%
HTN 30%
Obesity 27%
AF 5.5% (50% perm, 25% persis, 15% paroxys)
PD 1% of >65s
OSA 5-10%
Dementia 1% (7% of >65s)
AS 3% >65s, aortic sclerosis 25% of >65s (9% progress to AS)
GBS 1-2 in 100,000 (3-5% mortality)
MG 1 in 1000
Phaeo 1 in 100,000
Latex allergy 4.3% (9.7% in healthcare workers)
Penicillin allergy 10% reporting rate (90% of which are not truly allergic)
Anaphylaxis 1/5000-1/20,000, 3:1 female preponderance
Alcohol misuse 9% men, 4% women
PONV 30%

21
Q

Commonest cancers

A

Breast 15%
Lung 13%
Prostate 13%
Bowel 11%

22
Q

% metabolised

  • Des
  • Sevo
  • Iso
  • Xe
  • N2O
A 
Des 0.02
Sevo 5 
Iso 0.2 
Xe 0 
N2O 0
23
Q

Molecular weights

  • Des
  • Sevo
  • Iso
  • Xe
  • N2O
A 
Des 168 
Sevo 200
Iso 184 
Xe 131
N2O 44
24
Q

Oral bioavailability (%)

  • Morphine
  • Methadone
  • Tramadol
  • Pethidine
  • Codeine
A 
Morphine 30 
Methadone 75 
Tramadol 70 
Pethidine 50
Codeine 50 (but only 10% metab to morphine)
25
Q

Oxygen consumption (adult/child)

A

Adult: 3.5 ml/kg/min
Child: 6 ml/kg/min

26
Q

NNT

A

Carbamazepine in TGN: 1.8

Gabapentin in PHN: 4

27
Q

Mortality

- 30d postop emergency laparotomy

A
  • 30d postop emergency laparotomy 10-15%

FRCA (11 decks)

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