NULLS

Question 1

Mk

Answer 1

MNS null for for GYPA and GYPB

Question 2

U

Answer 2

MNS null for absence of GYPB

Question 3

Ena

Answer 3

MNS null for absence of GYPA

Question 4

p

Answer 4

P glob null. Missing both transferases galactosyltransferase and AcetylGalactoseaminytransferase

Question 5

K null

Answer 5

K null and is associated with McLeod syndrome and linked with other X-linked diseases like Chronic Granulomatous Disease which makes ab against ag in Kell system and reacts strongly with K null cells

Question 6

Fy(a-b-)

Answer 6

Duffy null. Common in West Africans and gives resistance to P vivax infection.

Question 7

Jk(a-b-) or JK3-

Answer 7

Kidd null that is rare in most pops. Often detected after being immunized to Kidd in pregnancy or blood transfusion

Question 8

In(Lu)

Answer 8

Dominant Lutheran null. Mutation in EKLF (adds antigens of Lu, P, and I groups onto cells)

Question 9

Recessive Lu

Answer 9

True Lu NULL. Normal functioning other antigens and makes Anti-LU3

Question 10

X-linked Lu

Answer 10

Rare seen in only one family. X-linked inhibitor of lutheran antigens only. Trace Lub found on cells

Question 11

Leach Type

Answer 11

Gerbich null. You will see elliptocytosis