Nucleotides and Nucleic acid Flashcards
Building blocks of nucleic acids
Nucleotides
Energy currency in cellular metabolism
ATP
It can also perform catalysis
RNA
Component of ribosomes, playing a role in protein synthesis
rRNA
Carry a genetic information from a gene to the ribosome
mRNA
Translate information in mRNA into an amino acid sequence
tRNA
It contains information needed to synthesize functional proteins and RNA
DNA
It plays a role in regulation
Nucleotides
What are the allosteric effectors
c-AMP and GMP
Structural components of many enzyme cofactors
NAD : CoASH
A secondary messenger
c-AMP
An important enzyme cofactor
NAD
A hydride transfer agent or reducing agent
NADH
NADH is derived from
Niacin
A pentose sugar (5 membered ring)
Ribose
An important derivative of ribose is
2’ deoxyribose or deoxyribose
An important regulatory nucleotide
Adenosine 3’,5’-cyclic monophosphate
A chain of nucleotides making the structure of DNA and RNA
Polynucleotide
A chain of amino acids linked by peptide bonds
Polypeptide
Can form “Hairpin double helix”
DNA
How many base pairs per turn
10.5 base pairs
The most common conformation for DNA
B form
Common for RNA because of different sugar pucker deeper minor groove , shallow major groove
A form
Is favored in conditions of low water
A form