Nucleotide met Flashcards

1
Q

degradation pathway

A

DNA/RNA -> denatured nucleotide -> oliconucleotide -remove PPD-> nucleotide -nucleotidase (remove P)-> nucleoside -nucleosidase (remove base) -> sugar

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2
Q

Pyrimidine pathway (products)

A

FAcoa -> malonyl -> ,slonyl semialdehyde -> beta-urido.. -> dihydrouracil -> uracil -> (salvage) -> cytocine

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3
Q

Pentose biosyn starter

A

hexose

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4
Q

Pentose syn pathwya

A

Pentose phosphorylation pathway -> PRPP -> pentose

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5
Q

Pyrimidine biosyn starter

A

Glutamine

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6
Q

Pyrimidine biosyn pathway

A

Glumatmine + hco3 - > carbomoid phosphate -> carbomoid aspartate -> dihydrorotate -> orotate - omp -> gmp -> utp (can be used as regulatory =)

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7
Q

Salvage pathway

A

PRPP -> Amp
PRPP -HRGPP-> I/gmp

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8
Q

UTP can be changed into

A

CTP

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9
Q

ATP can change GMP to

A

GDP and then GTP

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10
Q

adding ATP will

A

decrease ATP to ADP and increases the substrate by 1 P

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11
Q

what is PRPP

A

sugar

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12
Q

whats deoxy used for

A

DNA

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13
Q

ribonucleotide function

A

add P into the sugar to convert ribo to deoxyribo

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14
Q

ribo is OH or H

A

OH

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15
Q

glutathione is a carrier of

A

NADPH

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16
Q

thymidylate synthase function

A

dUMP -> dTMP

17
Q

for dTMP to be produced, the simplified pathway is to

A

add methyl then recycle

17
Q

for dTMP to be produced, the simplified pathway is to

A

add methyl then recycle

17
Q

for dTMP to be produced, the simplified pathway is to

A

add methyl then recycle

18
Q

purine syn pathways can be broken down into

A

salvage and de novo

19
Q

salvage pathway

A

ribose-5-phosphate -> PRPP

20
Q

de novo pathway

A

IMP -> AMP and GMP