lipid met Flashcards
What are the products of beta oxidation
NADH, FADH and acetyl-coa
how to transport acetylcoa
acetyl coa + carnitine ( to remove coa) -> acetylcarnitine (moved across the mêmbrane via ac1) -> (remove carnitine and connects coa via ac2) -> acetyl coa
even chain syn. products
nadh, fadh2 and acetyl coa
what is a thiolase
an enzyme that cuts the compound into halves ( keto acetyl coa + coa-> acetyl coa and coa)
odd chains
propanyl coa -(b12)-> succinyl coa
ketone body pathway
2 acetyl coa -(+coa)-> acetoacetyl coa -> remove acetyl coa -> acetoacetate-> acetone + alpha-beta-hrodroxylbutylrate
ketone body products
acetone and alpha-beta-hydroxylbutyraye
too much ketone body?
acidosis
fatty syn is the opposite of
beta oxidation
transport of FA syn
citrate (out of mitochon.) -> acetyl coa -> oxaloacetate (can regulate citrate) -> malonyl coa-> acetyl coa
ecosanoids pathways
cyclooxygenase and lipioxygenase
proglandins functions
physiological fumerions eg blood vessels tone
leukotreines function
inflammations
cholic acid makes
cherodeoxycholine acid
cholesterol makes
cholesterol ester
cholesterol makes (the second product)
pregnenolone -> progesterone -> cortisol, aldosterone, testosterone and estadiol
isoprenoids pathway
acetyl coa ->actoacetyl coa -(hmg synthase) -> hmg coa -> mevalonate —> isoprene units -> squalene -> squalene 2,3 epoxide -> cholesterol -> pregnenolone