Nucleic Acids & Proteins Flashcards

1
Q

Function of nucleic acids

A

Store, transmit, and express genetic information

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2
Q

Function of proteins

A

Do almost everything else that the cells need

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3
Q

The genome

A

Provides instructions for making that organism

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4
Q

DNA

A

Stores and transmits biological information

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5
Q

RNA

A

Expresses genetic information

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6
Q

Constituents of nucleotides

A
  • Phosphate group
  • Five carbon sugar
  • Nitrogen-containing aromatic base
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7
Q

Nucleoside

A

A nucleotide without a phosphate group

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8
Q

Deoxynucleotides

A

A nucleotide with a deoxy sugar

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9
Q

What bonds link nucleotides?

A

3’, 5’ phosphodiester bonds

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10
Q

Is the phosphate at the 3’ or 5’ end of the nucleotide?

A

5’

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11
Q

Is the hydroxyl at the 3’ or 5’ end of the nucleotide?

A

3’

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12
Q

A forms ___ hydrogen bonds with __

A

Two, T

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13
Q

G forms __ hydrogen bonds with ___

A

Three, C

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14
Q

Purines

A

Guanine and Adenine

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15
Q

Pyramidines

A

Cytosine and Thymine/Uracil

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16
Q

Proteins are polymers of ____

A

Amino acids

17
Q

There are L and D enantiomers. What enantiomer is used in proteins?

A

L enantiomer

18
Q

Polypeptide

A

Product of amino acid polymerization

- The process of elongating a chain of amino acids is called protein synthesis

19
Q

Non-polar amino acids

A

Glycine
Alanine
Leucine

20
Q

Polar, uncharged

A

Serine
Tyrosine
Threonine

21
Q

Polar, charged

A

Lysine
Aspartic acid
Glutamic acid

22
Q

The end of a polypeptide with the amino group is called the ____

A

N-terminus (beginning of the protein)

23
Q

The end of a polypeptide with the carboxyl group is called the ___

A

C-terminus (end of the protein)

24
Q

Amino acid covalent bond

A

Disulfide bonds

25
Amino acid non-covalent bonds
- Hydrogen bonds - Ionic bonds - Van der waals forces - Hydrophobic forces
26
What determines the 3D shape of a protein?
The bonds between the R groups
27
How does the secondary structure of a protein arise?
Results from hydrogen bonding between NH and CO groups along the polypeptide backbone
28
The alpha helix
R-groups jut-out from the spiral | - Some amino acids form helices; some don't
29
The beta sheet
Sheet-like conformation formed by multiple polypeptide strands - R groups jut-out on alternating sides of the sheet
30
What determines tertiary structure?
1. Hydrophobic residues avoiding water 2. Hydrophilic residues interacting with water 3. Repulsion of similarly charged residues 4. Attraction between oppositely charged residues
31
What determines quaternary structure?
Concerned with subunit interactions and assembly