Nucleic acids and proteins Flashcards
Proteins are made up of…
Proteins are made up of one or more polypeptide chains
Proteins
Functional groups
- COOH, carboxyl
- NH2, amino
Proteins
Where is the peptide link
O
||
C - NH
Proteins
Amino acids join via a …
condensation reaction
Proteins
How do polypeptides form
Combine numerous amino acids ( same side chains ) in a chain to form a polypeptide.
Proteins
Polypeptides are…
Monomers are…
- polymers (large molecule composed of many repeated units)
- Monomers (Basic unit-amino acids)
Proteins
-bond type
- Specific sequence of amino acids in the polypeptide chain
- Peptide bonds (covalent)
Proteins
-bond type
- Consists of localized coiling and folding of segment of the polypeptide chain.
- Hydrogen bonding between nearby peptide groups, form alpha helices, beta pleated sheets and random coils
Proteins
-bond type
- Structure due to global (spanning the entire molecule) folding and coiling.
- H bonding, ionic interactions, covalent bonding (disulfide bridges), hydrophobic interactions (since non- polar side chains tend to aggregate together.
Proteins
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- Multiple polypeptide chains (same four interactions)
- 3-D shape structure of a protein dictates its function. Globular proteins can only bind molecules of a complementary shape, like a lock and key
Nucleic acids
Define DNA
Is the chemical that encodes how each organism is made. It is the blueprint for the synthesis of every protein in your body (genes)
Nucleic acids
Define RNA
Is a chemical inside cells with a variety of functions. There are three types of RNA
Nucleic acids
RNA Messenger RNA (mRNA) - - - -
- mRNA carriers a copy of nucleotide sequence of DNA that specifics the amino acid sequence for a particular protein.
- Pre mRNA is formed by enzymes RNA polymerase
- Pre mRNA is processed to form mature mRNA
- The mature mRNA travel to cytosol where it binds to ribosomes ready for translation
Nucleic acids
RNA Ribosomal RNA (rRNA)
Together with proteins, rRNA forms organelles ribosome, ribosome are the site where information in mRNA is translated into chains of amino acid
Nucleic acids
RNA
Transfer RNA (tRNA)
-
-
- Transfer amino acid from the cytoplasm to ribosome where they join to form polypeptide chains.
- On tRNA there is a sequence of nucleotide (anticodon) which recognize a sequence of nucleotide in the mRNA