Nucleic acids and proteins Flashcards

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1
Q

Proteins are made up of…

A

Proteins are made up of one or more polypeptide chains

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2
Q

Proteins

Functional groups

A
  • COOH, carboxyl

- NH2, amino

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3
Q

Proteins

Where is the peptide link

A

O
||
C - NH

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4
Q

Proteins

Amino acids join via a …

A

condensation reaction

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5
Q

Proteins

How do polypeptides form

A

Combine numerous amino acids ( same side chains ) in a chain to form a polypeptide.

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6
Q

Proteins

Polypeptides are…
Monomers are…

A
  • polymers (large molecule composed of many repeated units)

- Monomers (Basic unit-amino acids)

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7
Q

Proteins

-bond type

A
  • Specific sequence of amino acids in the polypeptide chain

- Peptide bonds (covalent)

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8
Q

Proteins

-bond type

A
  • Consists of localized coiling and folding of segment of the polypeptide chain.
  • Hydrogen bonding between nearby peptide groups, form alpha helices, beta pleated sheets and random coils
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9
Q

Proteins

-bond type

A
  • Structure due to global (spanning the entire molecule) folding and coiling.
  • H bonding, ionic interactions, covalent bonding (disulfide bridges), hydrophobic interactions (since non- polar side chains tend to aggregate together.
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10
Q

Proteins

-

A
  • Multiple polypeptide chains (same four interactions)
  • 3-D shape structure of a protein dictates its function. Globular proteins can only bind molecules of a complementary shape, like a lock and key
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11
Q

Nucleic acids

Define DNA

A

Is the chemical that encodes how each organism is made. It is the blueprint for the synthesis of every protein in your body (genes)

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12
Q

Nucleic acids

Define RNA

A

Is a chemical inside cells with a variety of functions. There are three types of RNA

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13
Q

Nucleic acids

RNA
Messenger RNA (mRNA)
-
-
-
-
A
  • mRNA carriers a copy of nucleotide sequence of DNA that specifics the amino acid sequence for a particular protein.
  • Pre mRNA is formed by enzymes RNA polymerase
  • Pre mRNA is processed to form mature mRNA
  • The mature mRNA travel to cytosol where it binds to ribosomes ready for translation
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14
Q

Nucleic acids

RNA
Ribosomal RNA (rRNA)
A

Together with proteins, rRNA forms organelles ribosome, ribosome are the site where information in mRNA is translated into chains of amino acid

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15
Q

Nucleic acids

RNA
Transfer RNA (tRNA)
-
-

A
  • Transfer amino acid from the cytoplasm to ribosome where they join to form polypeptide chains.
  • On tRNA there is a sequence of nucleotide (anticodon) which recognize a sequence of nucleotide in the mRNA
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16
Q

Nucleic acid

-
-

A
  • Deoxyribose
  • Phosphate
  • Nitrogenous base
17
Q

Nucleic acid

RNA characteristics 
-
-
-
-
-
A
  • single stranded (oppoition of nitrogen bases)
  • RNA equivalent of thymine is urcail
  • Ribose
  • phosphate
  • nitrogenous base
18
Q

Nucleic acid

To join two nucleotide together…

A

the phosphate group of one nucleotide covalently bonds to the deoxyribose sugar of the next nucleotide

19
Q

Nucleic acid

Condensation between free nucleotides..

A

-Free nucleotide link together to form strands, How RNA and DNA is formed

20
Q

Nucleic acid

  • Purines (2)
  • Pyrimidines (1)
A
  • A + G

- T + U + C

21
Q

Nucleic acid

  • Adenine pairs with … via…
  • Guanine pairs with … via…
A

Thymine, by two weak hydrogen bonds

Cytosines, by three weak hydrogen bonds.