nucleic acids Flashcards
what is the monomer and polymer of a nucleic acid
monomer = nucleotide
polymer = polynucleotide (nucleic acid)
what 3 components make a nucleotide ?
1) phosphate group
2) nitrogenous base
3) (DNA) deoxyribose sugar
(RNA) ribose sugar
base pairs in DNA and RNA
DNA
Adenine-thymine
Cytosine-guanine
RNA
Adenine-uracil
Cytosine-guanine
what happens when many nucleotides join together ?
through a condensation reaction a polynucleotide chain is formed
this forms a phosphodiester bond between phosphate group and 3rd carbon
covalent bond which males sugar phosphate back bone very strong
must know
a nucleotide is a nitrogenous base
a DNA molecule has a double helix structure
this is due to the 2 polynucleotide chains held together by many week hydrogen bonds between specific complimentary base pairings
3 bases =
1 triplet
DNA codes for ?
the primary structure of polypeptide chains or proteins
DNA and RNA are important
information carrying molecules
Structure of DNA
1- Sugar phosphate backbone which provides strength
2- larger molecules so can store lots of information
3- base sequence allows info to be stored
4- coiled so compact
5- double stranded so replication can happen semi-conservatively
6- complimentary base pair so accurate replication
7- weak hydrogen bonds for unzipping
8- many weak hydrogen bonds so stable molecule
Compare and contrast DNA and RNA
DNA. - .RNA
Double stranded - single stranded
Deoxyribose - ribose
Thymine - Uracil
Has H bonds. - no H bonds
Semi conservative replication
1- DNA helicase (enzyme) attached and moves along DNA molecule, unwinding the DNA and breaks H bonds between complimentary Bases
2- two strands separate
3- each strand acts as a template, free nucleotides join to exposed bases via base pair ruling
4- DNA polymerase joins adjacent nucleotides together developing new strand via condensation reaction forming a phosphodiester bond
5- semi-conservative REP ensures 1 new strand and 1 old strand and is identical to DNA
Significance of Semi Conservative REP
- accurate replication occurs
- no mutations