nucleic acids Flashcards

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1
Q

what is the monomer and polymer of a nucleic acid

A

monomer = nucleotide
polymer = polynucleotide (nucleic acid)

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2
Q

what 3 components make a nucleotide ?

A

1) phosphate group
2) nitrogenous base
3) (DNA) deoxyribose sugar
(RNA) ribose sugar

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3
Q

base pairs in DNA and RNA

A

DNA
Adenine-thymine
Cytosine-guanine

RNA
Adenine-uracil
Cytosine-guanine

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4
Q

what happens when many nucleotides join together ?

A

through a condensation reaction a polynucleotide chain is formed
this forms a phosphodiester bond between phosphate group and 3rd carbon
covalent bond which males sugar phosphate back bone very strong

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5
Q

must know

A

a nucleotide is a nitrogenous base

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6
Q

a DNA molecule has a double helix structure

A

this is due to the 2 polynucleotide chains held together by many week hydrogen bonds between specific complimentary base pairings

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7
Q

3 bases =

A

1 triplet

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8
Q

DNA codes for ?

A

the primary structure of polypeptide chains or proteins

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9
Q

DNA and RNA are important

A

information carrying molecules

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10
Q

Structure of DNA

A

1- Sugar phosphate backbone which provides strength
2- larger molecules so can store lots of information
3- base sequence allows info to be stored
4- coiled so compact
5- double stranded so replication can happen semi-conservatively
6- complimentary base pair so accurate replication
7- weak hydrogen bonds for unzipping
8- many weak hydrogen bonds so stable molecule

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11
Q

Compare and contrast DNA and RNA

A

DNA. - .RNA

Double stranded - single stranded
Deoxyribose - ribose
Thymine - Uracil
Has H bonds. - no H bonds

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12
Q

Semi conservative replication

A

1- DNA helicase (enzyme) attached and moves along DNA molecule, unwinding the DNA and breaks H bonds between complimentary Bases

2- two strands separate

3- each strand acts as a template, free nucleotides join to exposed bases via base pair ruling

4- DNA polymerase joins adjacent nucleotides together developing new strand via condensation reaction forming a phosphodiester bond

5- semi-conservative REP ensures 1 new strand and 1 old strand and is identical to DNA

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13
Q

Significance of Semi Conservative REP

A
  • accurate replication occurs
  • no mutations
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