Cell Cycle Flashcards

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1
Q

Name the 3 stages of cell cycle

A

Interphase
Mitosis
Cytokinesis

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2
Q

Explain the 3 steps in interphase

A

G1 - cell increases in size and new biomass is created

S - semi conservative replication

G2 - cell gets ready for division
ATP is synthesised and stored
New organelles synthesised

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3
Q

Explain cytokineses

A

When the cytoplasm splits into 2 (mitosis) or 4 (meiosis) new cells

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4
Q

Define Gene

A

Section of DNA which codes for a specific protein

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5
Q

Explain Prophase

A

1- nuclear membrane starts to break down
2- centrioles move to the poles and start spindle fibre production
3- chromosomes super coil and become visible
4- chromosomes are now presented as sister chromatids

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6
Q

Purpose of mitosis

A

To increase cell number and growth of of organelles
To repair damaged tissues
To replace dead/worn out cells

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7
Q

Purpose of Metaphase

A

1- centrioles complete production of spindle fibre
2- spindle fibre attach to chromosomes centromere
3- chromosomes align on the equator

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8
Q

Purpose of Anaphase

A

1- spindle fibre shorten
2- centromere split
3- identical sister chromatids pulled to opposite poles
4- v shape is created

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9
Q

Purpose of Telophase

A

1- nuclear membrane starts to form around each set of chromosomes
2- chromosomes unwind and become invisible

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10
Q

Unregulated mitosis

A

Cells go under cell division in mitosis
They differentiate into tissue and organs

If mutation occurs - uncontrolled cell division can occur
This is rapid and a tumour develops
If it goes into the tissue/body this means cancer

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11
Q

What is binary fission

A

It’s Asexual reproduction in prokaryotic cells which involves

  • replication of circular DNA and plasmids
  • cytoplasm dividing into 2 daughter cells, each with one copy of DNA and variable number of plasmids
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12
Q

How does binary fission divide into 2

A

Cell elongates from the middle
Separates 2 DNA molecules
New cell wall (murein) formed down the middle
Divides into 2 cells

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13
Q

Mitotic index equation

A

MI = N.O condensed chromosomes
——————————————
Total N.O cells

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14
Q

Haploid definition

A

Single set of chromosomes

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15
Q

Diploid definition

A

Two sets of chromosomes

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16
Q

Process of meiosis

A

Dna replicated in S phase
Chromosomes go through 2 nuclear divisions (Pmat)

1st division - homogulous chromosomes (2n) pair up and separate forming (2n)

2nd division - chromatids (2n) separate (1n) in one cell

17
Q

Meiosis extra info

A

Diploid organisms produce haploid gametes
Creates 4 genetically identical daughter cells
Gametes (1n) fuse firming zygote (2n)

Ensure chromosome number stays constant from one generation to the next

18
Q

Crossing over - (1st division) P M

A

1- homogulous chromosomes associate (bivalent forms)
2- chiasmata form (entanglement)
3- equal lengths of alleles exchanged
4- new combination of alleles produced

19
Q

Independent segregation (1st division ) Metaphase

A

Homologous chromosomes attach to spindle fibres and they pair up side y side and can be reshuffled in any combination

20
Q

Importance of meiosis

A

1- halves the number of chromosomes
2- restores full number at fertilisation