nucleic acid inhibitors Flashcards
antibacterial spec of co-trimoaxzole
GIT pathogens
-E.coli
-Shigella
-V. cholera
-S. typhi
UTI pathogens
-E.coli , proteus , klebisella, enterobacter
Resp pathogens
-H.influnzae
-M. cattaharlis
-S.pnuemonia
-pneumcytitis jerovecii
nocardia, MRSA, L.monocytogenes
indications of quinolones
UTI and prostatitis
GI = gastroenteritis
Septicemia
Resp infections = bronchitis , pneumonia , tuberculosis
STDs = cervicitis, gonorrhea , urethritis
skin and soft tissue infections
Bone, joint , eye , ear infections
AE of quinolones
prolongation of QT and arrthimyas
avoided in pregnancy
tendiopathy and arthropathy
GI disturbance (C.diff colitis)
Changes in glucose levels
indications of co-trimaoxzole
traveler diarrhea
Uncomplicated UTI
Pneumocytitis
acute otitis media
exacerbation of COPD
AE of course-trimazole
-Crystalluria
-Folic acid deficiency
megoblastic anemia and leukopenia
-Hypersenstivity (RASH / PRURITITS)
-Gi effects
most common AE of quinolones
GI disturbance = C.diff colitis
co-trimoaxzole is not active against
pseudomonas aerignosa
B.fragilis
most anaerobes
penicillin-resistant S.pneumonia
spec of daptomycin
gram positive
streptococci
staphylococci (MRSA)
Vancomycin-susceptible strains of enterococci (e.faecilis)
spec of nitrofurantoin
broad spec gram positive and negative including enterococci
spec of metronidazole / secnidazole
Anaerobes:
B.fragilis
C.diff
Gardenella vaginalis
Gram -ve ; H.pylori
Protoza:
Giardia lambila
trichomonas vaginalis
what bacteria are resistant towards nitrofurantoin
pseudomonas
proteus
klebsillea
indication of daptomycin
skin and soft tissue infections
Bacteremia ; those with right sided infective endocarditis
