Nuclear receptors Flashcards
1
Q
Major receptor superfamilies
A
2
Q
How can receptors be regulated?
A
3
Q
Where are nuclear receptors?
- What do they regulate?
- What do NRs bind to?
- If they do not have a ______, what are they called/
- What happens when a _______ binds?
A
4
Q
Natural NR ligands
A
5
Q
Synthetic NR ligands
A
6
Q
Xenobiotic NR ligands
A
7
Q
What do NR ligands act as?
A
8
Q
NR domain structure
A
9
Q
Ligand binding domain
A
10
Q
Function of NR domain
A
11
Q
What promote NR complexes?
A
12
Q
CoRepressor complexes
A
13
Q
CoActivator complexes
A
14
Q
LBD = Heterodimers + RXR
A
15
Q
What is the activation helix?
A
