NTIs Flashcards
What pathogens are associated with are human African, trypanosomiasis, chugs disease and leishmaniasis
Protozoan
What pathogens are associated with Buruli Ulcer, Leprosty and trachoma
Bacterial
What pathogens are associated with ascariasis, hookworm, trichuriasis, schistosomiasis, lymphatic filariasis etc.
Helminth
Give examples of intestinal worms
Ascariasis, hookworm, trichuriasis
What is MDA and when is it possible
Mass drug administration
Drugs are safe and effective + cheap
Diagnosis is difficult or inaccurate
Give an example of a miracle drug
Praziquantel Albendazole Mebendazole Mectizan DEC Zithromycin
Describe schistosomiasis
Bilharzia
Africa
Intermediate host is a fresh water snail
Complete cycle is excretion into fresh water
What does schistosomiasis cause and how is it treated
Blood in urine, bladder fibrosis, cancer, high BP
Praziquantel (+clean water)
What is used to treat soil transmitted helminths
albendazole and mebendazole
Describe lymphatic filariasis
Adult worms live in the lymphatic nodes
Transmission by mosquitos taking up larvae
SE Asia and Africa
How is lymphatic filariasis managed
Albendazole and mectizan/DEC
Describe onchocerciasis
worms live under the skin and larvae destroy the eye
Africa
Black fly host
How is onchocerciasis managed
Mectizan
Treatment near rivers
What has helped to improve NTIs
Pharmaceutical industry e.g. Johnson and Johnson
organisations e.g. WHO, bank
Ministries of health e.g. RTI. CBM
Describe dermal leishmania
sandfly host (small)
self-cures
fever, weight loss, enlarged liver
Anaemia + low WBC
