NT (book) Flashcards
Function of DA
Fine muscle movement
Integration of thoughts & emotions
Decision making
Stim. Hypothalamus to release hormones (ex: sex, thyroid, adrenal)
Increase of DA vs Decrease of DA
Increase= (schiz like symptoms) mania/psychosis
Decrease= Parkinson’s disease, depression
Norepinephrine (NE) function
Mood
Attention & arousal
stim. Sympathetic branch of ANS for “flight or fight”
Increase vs Decrease of NE
Increase: mania, anxiety, psychosis
Decrease: depression
Serotonin function (5-HT)
Mood
Sleep regulation
Hunger
Pain perception
Aggression & libido
Hormonal activity
Increase vs decrease of 5HT
Increase: anxiety
Decrease: depression
Histamine function
Alertness
Inflammatory response
Stim. Gastric response
Increase vs decrease histamine
No increase affects
Decrease: sedation, weight gain
GABA function
Inhibitor NT
Reduces anxiety, excitation, aggression
May play role in pain perception
Anticonvulsant & muscle relaxer effects
May impair cognition and psychomotor functioning
Increase vs decrease GABA
Increase: reduce anxiety
Decrease: mania, anxiety, psychosis
glutamate function
Excitatory NT
Learning and memory
Increase vs decrease of glutamate
Increase too much:
prolonged increase can kill neurons (neurotoxicity)
Neurodegeneration in Alzheimer’s
Increase:
Improvement of cognitive performance in behavioral tasks
Decrease:
Psychosis
ACh function
Plays a role in learning and memory
Regulates mood: mania, sexual aggression
Affects sexual and aggressive behavior
Stim, para sympathetic nervous system
