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NT Flashcards

1
Q

AchRN pore et pied

A

3nm 6nm

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2
Q

AchRN structure

A

5SU
each one with 4STM:
-NH2COOH EC
-boucle P
-paroi interne
-recepteur ach

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3
Q

1 quantum d’Ach

A

2pA

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4
Q

courant conductance unitaire

A

1.3pA
60pS

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5
Q

recepteur muscarinique

A

M1-M5
M2-M4 Go Gi
M1.M3.M5 Gq G11

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6
Q

Recepteur dopaminergique

A

so métabotrope

D1-D5

D1 et D5 adénylate cyclase act, Gs

D2 D3 D4 adénylate inhib, Gi Go

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7
Q

NMDA conductance vitesse

A

50pS
8-10ms

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8
Q

n-NMDA conductance vitesse

A

8pS
1-2ms

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9
Q

NMDA et n-NMDA caractéristiques

A

tetramères chaque sous unités comprend 4segments dont 3stm

NH2 EC COOH IC

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10
Q

mGLUr

A

3classes

classe I: Gq

CLASSE II III: Gi

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11
Q

GABA-A structure conductance

A

pentamère chaque sous unités 4stm

NH2 COOH IC
pore 0.5nm

20pS

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12
Q

GABA-B

A

potéine Gi

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13
Q

neuropeptides

A

3-100 AA

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14
Q

agoniste msucarinique

A

muscarine
pilocarpine

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15
Q

antagoniste muscarinique reversible compétitif

A

atropine

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16
Q

antagoniste non réversibles

A

pirenzépine

17
Q

agoniste recepteur nicotinique

18
Q

antagoniste reversible compet nicotinique

A

curare
dp: succynilcholine
ndp: atricrium

19
Q

antagoniste non reversible non compet nicotinique

A

neuroleptique

20
Q

inhibiteurs esterase acétylcholine

A

reversible: prostigmine

non reversible: organo phosphorés insecticides soufrés

21
Q

agoniste antagoniste recepteur dopamine

A

agoniste: apomorphine
antagoniste: neuroleptiques

22
Q

antagoniste glutamate nicotinique NMDA

A

mémantine

23
Q

antagoniste recepteur métabotrope glutamate

24
Q

recepteur gaba agoniste ionotrope

A

benzo
barbi

25
Q

recepteur gaba antagoniste ionotrope

A

bicuculline

26
Q

recepteur gaba antagoniste métabotrope

Chiffres (9 decks)

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