NSG 219- Pharmacology Flashcards

1
Q

What is pharmacokinetics? What is ADME?

A

How medications travel throughout the body. Absorption, Distribution, Metabolism Excretion

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2
Q

What is absorption?

A

Transmission of med from site of administration

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3
Q

What are the most common routes for absorption?

A

Eternal and parenteral

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4
Q

What determines intensity of a medication effect?

A

The amount absorbed

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5
Q

What determines how soon medication takes effect?

A

The rate

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6
Q

What effects the rate and amount of absorption?

A

Route

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7
Q

What is distribution?

A

The transport of meds throughout the body

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8
Q

What factors influence the distribution of meds?

A

Circulation, permeability of membrane and plasma protein binding

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9
Q

What is metabolism? Where does it happen?

A

How quickly a med is processed. Happens usually in the liver, but can happen in the lungs, kidney and blood vessels

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10
Q

What factors effect metabolism?

A

Age, nutritional status, first pass effect, similar metabolic pathway

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11
Q

What is excretion? How is this done?

A

Eliminating a med from the body. Done by the kidneys

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12
Q

What labs must be monitored?

A

BUN and Creatinine

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13
Q

Oral Meds: Barrier to absorption and Absorption pattern

A

Barrier to Absorption: Cells of GI. Absorption Pattern: Varies based on many factors

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14
Q

Sublingual Meds: Barrier to absorption and Absorption pattern

A

Barrier to absorption: Swallowing before dissolved. Absorption pattern: Quick

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15
Q

Other Mucous membrane Meds: Barrier to absorption and Absorption pattern

A

Barrier to absorption: stool, or tissue. Absorption pattern: easy

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16
Q

Inhalation Meds: Barrier to absorption and Absorption pattern

A

Barrier to Absorption: Inspiratory effect. Absorption pattern: Rapid

17
Q

Intradermal or Topical Meds: Barrier to absorption and Absorption pattern

A

Barrier to absorption: Cells. Absorption pattern: slow

18
Q

SubQ and IM Meds: Barrier to absorption and Absorption pattern

A

No barrier and rapid absorption

19
Q

IV Meds: Barrier to absorption and Absorption pattern

A

No barrier and immediate absorption

20
Q

What is Half-life?

A

Time it takes for the amount of med to decrease by 50% in the body

21
Q

Short half-life

A

Med leaves body quickly (4-8 hours)

22
Q

Long half life

A

Med stays in body longer (24+ hours)