NSAIDs Flashcards by Yasser Beeharry | Brainscape

Q

Which PGs are vasodilators in CVS?

A

PGE2 and PGI2

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Q

Which PGs are vasoconstrictors in CVS?

A

PGF2 and TXA2

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Q

Uses of PGE analogs?

A

Abortion
Erectile dysfunction
Peptic ulcer

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Q

Uses of PGI analogs?

A

Pulmonary Hypertension

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Q

Best NSAID for chronic gout?

A

Allopurinol

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Q

Best NSAID for chronic gout?

A

Allopurinol

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Q

Misoprostol is an analogue of what? Use?

A

PGE1
Protection of mucosal lining in stomach

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Q

Contraindications of paracetamol

A

Nephritis
Hepatitis

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Q

Which nsaids undergo enterohepatic circulation?

A

Long-acting NSAIDs: Piroxicam

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Q

Effect of COX Inhibition on kidney?

A

Water retention
Decreased renal perfusion
-> Increased hypertension

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