NSAIDs Flashcards
1
Q
what is the mechanism of NSAIDs?
A
COX (cyclooxygenase) inhibitors
2
Q
give some examples of NSAIDs (8)
A
ibuprofen
naproxen
diclofenac
aspirin (low-dose)
celecoxib
mefanaluic acid
etoricoxib
indomethacin
3
Q
when should you consult Dr before NSAIDs? (possible contraindications)
A
over 65
pregnant/breastfeeding
asthma
stomach ulcers
BP problems
heart, liver, kidney, bowel or circulation problems
4
Q
side effects of NSAIDs
A
indigestion
stomach ulcers - can cause internal bleedings or anaemia
flu-like symptoms
heart failure/attack
stroke
5
Q
drug interactions of NSAIDs
A
other NSAIDs
anti-coagulants e.g. warfarin
ciclosporin
diuretics
lithium
methotrexate
SSRIs (anti-depressants)