nPsych Vocab Flashcards

1
Q

Inability to perform transitive or intransitive gestures to command. Performance usually but not invariably improves with imitation and usually becomes normal when the actual object to use is provided.

A

Ideomotor apraxia.

NOTES: Left handed ideomotor apraxia may be seen with lesions of the corpus callosum. Conceptual apraxia and ideomotor apraxia may coexist, most often in the setting of Alzheimer disease.

Ideomotor apraxia is generally associated with left hemisphere lesions (inferior parietal lobule or supplementary motor area). Partial deficits, e.g., ideomotor apraxia in pantomime but preserved ability to discriminate correct from incorrect pantomimes, or vice versa, may be seen.

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2
Q

What condition manifests the following errors?

Body part as tool errors, in which the hand is used to form the tool being demonstrated, are particularly common (for example, persisting in using the fingers as the blades of scissors despite correction).

Errors of detail, for example imitating the twisting movement of the forearm necessary to use a screwdriver but not maintaining the handgrip on the axis of rotation, are also frequent.

A

Ideomotor Apraxia

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3
Q

What condition is assessed by asking the patient to pantomime the use of common objects (e.g., hammer, scissors, screwdriver, key) and symbolic gestures (e.g., saluting, making the thumb-out gesture of a hitchhiker).

A

Ideomotor Apraxia

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4
Q

This theory of aging postulates that some genes that are beneficial at earlier ages are harmful at later ages.

A gene that increases survival to reproductive age will be favored by natural selection if it decreases the chances of dying prior to age 20. Harmful late-acting genes can remain in a population if they have a beneficial effect early in life (e.g., increasing fitness or increasing reproductive success).

A

Antagonistic pleiotropy

NOTES: Natural selection will frequently maximize vigor in youth at the expense of vigor later on and thereby produce a declining vigor (aging) during adult life (Greek anti-, against + agonizesthai, to struggle, from agon, contest; ple(i)on, more + -trope, change).

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5
Q

The development of an adverse event resulting from negative expectations associated with expecting treatment failure.

A

Nocebo effect

The nocebo effect represents the negative side of a placebo effect and may not only occur in response to taking an inactive drug but also in the context of clinical trials (or clinical care) when placebos are not administered (Latin nocebo, I will harm; c.f., placebo, I will please).

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6
Q

An involuntary slow, regular writhing movement resulting from kernicterus, hypoxia, prematurity, and may also be present in many diseases of the basal ganglia.

A

Athetosis.

Distal limbs are usually more affected, although athetosis may be present in any muscle group. Willed movement of one hand may result in synkinesia, the contraction of distant muscles. Athetosis is commonly associated with intellectual disability, although relatively normal IQs may be seen if damage is restricted to the basal ganglia (Greek a-, without; from tithemai, to place myself).

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7
Q

A consonant trigram (e.g., d-w-l) is presented, and the task is to recall the three-letter sequence following distractor delays of differing lengths. Typically, the patient is instructed to count backward by 3’s, and distractor intervals of 9, 18, and 36 seconds are employed.

A

Auditory consonant trigrams.

Notes: This is a procedure rather than a formal test, however, and the above parameters can be modified to suit individual patient needs or the requirements of a particular experiment. Auditory consonant trigram testing has been demonstrated to be sensitive to certain types of frontal lobe impairment

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8
Q

What is the Brown-Peterson technique?

A

Essentially, the inclusion of a distraction trial or task to prevent rehearsal on memory tasks.

Notes: After hearing a trigram participants were asked to count backwards in threes or fours from a specified random number until they saw a red light appear (then they recalled the trigram). This is known as the brown peterson technique, and the purpose was to prevent rehearsal.

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9
Q

Generalized seizures that result in a sudden loss of motor tone. These spells typically occur without warning, and patients run the risk of head or other physical injury. Protective headgear is sometimes used by children and adults.

A

Atonic seizures/drop attacks

Notes: Atonic seizures tend to be resistant to anti-epilepsy drug therapy.

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10
Q

Method of assessment that emphasizes the qualitative aspects of how patients attempt to solve problems rather than relying solely on quantitative scores.

A

Boston process approach

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11
Q

This approach was popularized by Edith Kaplan that analyzes the process by which a specific score is achieved including an analysis of the errors that are generated during task performance

A

Boston process approach

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12
Q

Parkinsonism that develops as a result of ischemic cerebrovascular disease, and generally accounts for < 5% of cases classified of parkinsonian patients but figures of up to 30% of strokes may cause some parkinsonism.

A

Vascular parkinsonism (AKA arteriosclerotic parkinsonism, vascular pseudo-parkinsonism, and lower body parkinsonism)

Vascular parkinsonism differs from idiopathic PD by greater gait disorder (frequently freezing of gait), postural instability, and falls rather than with upper limb rest tremor or bradykinesia. Pyramidal sign findings and subcortical dementia are more common than in PD.

The therapeutic options for vascular parkinsonism are largely limited to levodopa, although poor or non-sustained response to levodopa is common.

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13
Q

A test of sustained and divided auditory attention in which a series of randomized numbers is presented. The task is to add each number to the digit immediately preceding it. For numbers “2-8-6-1-9,” for example, the correct responses beginning after number “8” are “10-14-7-10.” The digits are presented at four differing rates.

A

Paced Auditory Serial Addition Test (PASAT)

Note: The PASAT has predictive ability for return to work following traumatic brain trauma. The PASAT is susceptible to practice effects, and is also negatively affected by increasing age, decreasing IQ, and low math ability/math anxiety

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14
Q

The tendency to walk backward involuntarily leading to postural instability and which is often seen in Parkinson’s disease and other extrapyramidal diseases.

A

Retropulsion

NOTE: Retropulsion is also observed when testing postural stability using the pull test, which is part of the Unified Parkinson’s Disease Rating Scale (UPDRS), in which an examiner standing behind a patient gives sudden, brief backward pull to the patient’s shoulders to elicit possible retropulsion

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15
Q

A syndrome that affects an individuals’ phonological ability and orthographic memory. Deep agraphia is often the result of a lesion involving the left parietal region (supramarginal gyrus or insula). Individuals can neither remember how words look when spelled correctly, nor sound them out to determine spelling.

A

Deep agraphia

Additional Notes: A syndrome that is similar to phonological agraphia in that there is an impairment of the nonlexical spelling route so that nonwords and unfamiliar words are misspelled. There is also damage to the lexical spelling route, however, resulting in semantic errors in writing.

Spelling is strongly influenced by word class (content words are easier to spell than function words), frequency (high frequency words are easier to spell than low frequency words), and imagery/concreteness (high imagery words are easier to spell than low imagery words).

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16
Q

Differential performance of aphasic patients that is related to word type or class.

A

Word class effects

NOTES: Broca aphasics omit more function words (grammatical or connecting words) than content words (nouns and verbs).

Patients with reading disorders may make more errors reading abstract than concrete nouns.

17
Q

Technique used to demonstrate psychogenic hemiparesis. While supine, the patient’s paretic arm is raised over the face and is dropped by the examiner. Patients with psychogenic hemiparesis typically avoid hitting their face, demonstrating preserved muscle strength.

A

Face-Hand Test.

18
Q

Method of double simultaneous stimulation designed to assess tactile extinction. Both hands, a face and hand, or both cheeks are touched simultaneously.

A

Face-Hand Test.

19
Q

A standardized instrument widely used to monitor disease progression and treatment response in clinical settings and as end points in drug trials. Items are scored from 0 (normal) to 4 (severely affected), with a composite score ranging from 0 points (no disability) to 199 points (severe disability).

A

Unified Parkinson Disease Rating Scale (UPDRS).A standardized instrument widely used to monitor disease progression and treatment response in clinical settings and as end points in drug trials. Items are scored from 0 (normal) to 4 (severely affected), with a composite score ranging from 0 points (no disability) to 199 points (severe disability). The scale assesses the following areas: Cognition, mood, motivation, and thought disorder (Part I); Activities of daily living and tremor or sensory symptoms in walking, both in an “on” and “off” state (Part II); motor symptoms such as bradykinesia, tremor, speech, facial expression, rising from a chair (Part III); Therapy complications including dyskinesias, motor fluctuations, anorexia, sleep disturbance, etc. (Part IV); Overall rating of disease severity based on a modified Hoehn and Yahr Scale (Part V); and Degree of dependency based on the Schwab andEngland Activities of Daily Living Scale (Part VI)

20
Q

A purported perceptual disorder that causes an individual to experience visual distortions and illusions when viewing text, and thus interferes with reading ability.

A

Scotopic sensitivity syndrome (Irlen syndrome)

Additional notes: Individually prescribed colored filters, either tinted spectacle lenses or colored sheets of plastic (overlays), are posited to alleviate these visual distortions, removing an “obstacle” to reading instruction. The existence of scotopic sensitivity syndrome and the efficacy of the colored-filter treatment are controversial.

21
Q

Speech disorder of cerebellar origin characterized by variable intonation associated with involuntary interruption between syllables. Each syllable may be uttered with more or less force than normal (“explosive” or “staccato” speech). In addition, speech is slow. Scanning speech is one of the characteristics of ataxic dysarthria.

A

Scanning speech (ataxic dysarthria).

22
Q

A standardized mental status examination with scores ranging from 0-30 that was developed to be sensitive to early cognitive impairment and progressive dementia in patients who are relatively well educated. It reportedly has greater sensitivity to mild cognitive impairment (MCI) than other screening measures due to multiple memory components including a brief recognition test for information presented as a prose passage in addition to more traditional recall of concrete nouns (animal naming).

A

Saint Louis University Mental Status Examination (SLUMS).

23
Q

A genetic disease of childhood transmitted as a sex-linked recessive trait marked by diffuse abnormality of the cerebral white matter and adrenal atrophy. It is characterized by cognitive impairment that progresses to dementia and by aphasia, apraxia, dysarthria, and impaired vision. An adult onset variant exists in which the disease progresses more slowly, although it too is associated with deterioration of brain function

A

Adrenoleukodystrophy.

(adrenal + Greek leukos, white; dys-, hard, ill, bad; trophe, nourishment, from trephein, to nourish).

24
Q

A technique developed for decreasing seizure frequency in patients with medically refractory focal epilepsy. A pacemaker-like device is attached to the tenth (vagus) cranial nerve to deliver electrical pulses.

A

Vagus nerve stimulation (VNS).

Notes: The effectiveness of VNS stimulation generally improves over the initial post-operative year. VNS is also an FDA approved treatment option for medically refractory depression, and VNS application for other areas including obesity and cognition are being investigated. Possible side effects include voice alteration, dysphagia, coughing, neck pain, and cardiac arrhythmia.

25
Q

Rapidly progressive and potentially reversible cognitive impairment associated with neurologic autoimmunity. Autoimmune dementias have historically be been classified eponymously (e.g., Morvan syndrome, Hashimoto encephalopathy, syndromically (e.g., progressive encephalomyelopathy with rigidity and myoclonus), serologically (e.g., VGKC antibody–associated encephalopathy), or pathologically (e.g., nonvasculitic autoimmune meningoencephalitis), and the presence of neural autoantibodies are suggestive of paraneoplastic causes. Intravenous corticosteroids often aid in diagnosis and chronic therapy.

A

Autoimmune dementia

26
Q

A condition from emboli that pass through the termination of the basilar artery and occlude the thalamoperforant arteries. It consists of visual, oculomotor, and behavioral abnormalities without significant motor dysfunction. Memory impairment is common with infarction of the medial thalamus, although it is not as dense as that associated with hippocampal infarction

A

Top-of-the-basilar syndrome.

Caplan, L.R. (1980). “Top of the basilar” syndrome. Neurology, 30, 72-79].

27
Q

A planning test assessing the ability to time-manage and distribute the execution of several tasks during a 10-minute time frame. It contains three main assignments (Dictation, Arithmetic, Object Naming), each of which has two parts. The task is to attempt at least part of each of the 6 tasks within 10 minutes, with the constraint that they cannot perform both parts of the same task consecutively.

Dictation consists of two topics to tell a story about: a holiday (version A) and a happy event (version B).

Arithmetic consists of two booklets (Version A and B) with 60 arithmetic problems.

Object naming consists of two booklets (Version A and B) containing 60 pictures of objects with the task to name each picture in writing. The score is the number of tests attempted (maximum= 6) minus the number of time the switching rule is violated.

A

Modified Six Elements (6E)

Extra Notes: The Modified 6 Elements is a simplified version of the original Shallice and Burgess (1991) task, and is subtest from the Behavioral Assessment of the Dysexecutive Syndrome (BADS)

28
Q

What is the Multi-trait multi-method matrix (MTMM)?

A

An approach to establishing construct validity in a set of measures.

Multi-trait refers to the inclusion of similar and dissimilar traits to establish both convergent (one trait and two methods) and discriminant validity (two traits and one method), and

Multi-Method refers to separate approaches for trait characterization to determine the possible contribution of shared method variance.