NPCA (must knows) (both NCCN and Perez) (under construction) Flashcards
NPCA
AJCC Staging 2017
Identify the T Stage:
parapharyngeal space involvement
T2
NPCA
AJCC Staging 2017
Identify the T Stage:
medial and lateral pterygoid “muscles” extension
T2
NPCA
AJCC Staging 2017
Identify the T Stage:
prevertebral muscles involvement
T2
NPCA
AJCC Staging 2017
Identify the T Stage:
hypopharyngeal involvement
T4
NPCA
AJCC Staging 2017
Identify the T Stage:
infiltration of the bony structures of the skull base
T3
NPCA
AJCC Staging 2017
Identify the T Stage:
involvement of pterygoid plates
T3
NPCA
AJCC Staging 2017
Identify the T Stage:
involvement of paranasal siuses
T3
NPCA
AJCC Staging 2017
Identify the T Stage:
extension to nasal cavity
T1
NPCA
AJCC Staging 2017
Identify the T Stage:
oropharyngeal extension
T1
NPCA
AJCC Staging 2017
Identify the T Stage:
no tumor identified but EBV+ cervical node+
T0
NPCA
AJCC Staging 2017
Identify the N Stage:
solitary lymph node less 4 cm, level 4
N3
unilateral or bilateral metastasis in cervical lymph node(s),
larger than 6 cm,
and/or
“extension below the caudal border of the cricoid.”
NPCA
AJCC Staging 2017
Identify the N Stage:
multiple bilateral retropharyngeal lymph nodes none larger than 6 cm.
N1
Unilateral metastasis in cervical nodes above the cricoid, none more than 6 cm,
and/or
“bilateral RPN”
NPCA
AJCC Staging 2017
Identify the N Stage:
multiple bilateral lymph nodes at the level 2-3 cervical chains, none larger than 6 cm.
N2
bilateral above the cricoid, none more than 6
NPCA
AJCC Staging
Identify the grade:
Well differentiated
NONE
Grading system is not used for NPCa.
NPCA
AJCC Staging
Identify the Prognostic Group
T0, N2, M0
Stage III
T0-2 N1-2
or
T3 N0-2
NPCA
AJCC Staging
Identify the Prognostic Group
T4, N0 M0
Stage IVA
Any T, N3
T4, N0-2
NPCA
AJCC Staging
Identify the Prognostic Group
T1, N0, M0
Stage I
T1 N0
NPCA
AJCC Staging
Identify the Prognostic Group
T2, N1, M0
Stage II
T0-1, N0-1
T2, N0-1
NPCA
What is the preferred treatment for Stage I disease?
RT alone
NPCA
What is the preferred treatment for Stage II-IVA disease?
induction chemo + CCRT
or
CCRT + adjv. chemo
CCRT alone is category 2B
NPCA
What is the preferred chemotherapy regimen for CCRT?
cisplatin
NPCA
What is the preferred drug combination for induction therapy?
Cisplatin+Gemcitabine
(cat1)
TPF (cat1 only for non-EBV associated)
NPCA
What is the preferred drug combination for adjuvant therapy?
PF
NPCA
Where is the most common origin of NPCA?
lateral walls (incl. fossa of Rosenmüller)
