NPCA (must knows) (both NCCN and Perez) (under construction) Flashcards

1
Q

NPCA
AJCC Staging 2017

Identify the T Stage:

parapharyngeal space involvement

A

T2

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2
Q

NPCA
AJCC Staging 2017

Identify the T Stage:

medial and lateral pterygoid “muscles” extension

A

T2

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3
Q

NPCA
AJCC Staging 2017

Identify the T Stage:

prevertebral muscles involvement

A

T2

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4
Q

NPCA
AJCC Staging 2017

Identify the T Stage:

hypopharyngeal involvement

A

T4

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5
Q

NPCA
AJCC Staging 2017

Identify the T Stage:

infiltration of the bony structures of the skull base

A

T3

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6
Q

NPCA
AJCC Staging 2017

Identify the T Stage:

involvement of pterygoid plates

A

T3

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7
Q

NPCA
AJCC Staging 2017

Identify the T Stage:

involvement of paranasal siuses

A

T3

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8
Q

NPCA
AJCC Staging 2017

Identify the T Stage:

extension to nasal cavity

A

T1

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9
Q

NPCA
AJCC Staging 2017

Identify the T Stage:

oropharyngeal extension

A

T1

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10
Q

NPCA
AJCC Staging 2017

Identify the T Stage:

no tumor identified but EBV+ cervical node+

A

T0

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11
Q

NPCA
AJCC Staging 2017

Identify the N Stage:

solitary lymph node less 4 cm, level 4

A

N3

unilateral or bilateral metastasis in cervical lymph node(s),

larger than 6 cm,

and/or

“extension below the caudal border of the cricoid.”

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12
Q

NPCA
AJCC Staging 2017

Identify the N Stage:

multiple bilateral retropharyngeal lymph nodes none larger than 6 cm.

A

N1

Unilateral metastasis in cervical nodes above the cricoid, none more than 6 cm,

and/or

“bilateral RPN”

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13
Q

NPCA
AJCC Staging 2017

Identify the N Stage:

multiple bilateral lymph nodes at the level 2-3 cervical chains, none larger than 6 cm.

A

N2

bilateral above the cricoid, none more than 6

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14
Q

NPCA
AJCC Staging

Identify the grade:

Well differentiated

A

NONE

Grading system is not used for NPCa.

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15
Q

NPCA
AJCC Staging

Identify the Prognostic Group

T0, N2, M0

A

Stage III

T0-2 N1-2
or
T3 N0-2

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16
Q

NPCA
AJCC Staging

Identify the Prognostic Group

T4, N0 M0

A

Stage IVA

Any T, N3
T4, N0-2

17
Q

NPCA
AJCC Staging

Identify the Prognostic Group

T1, N0, M0

A

Stage I

T1 N0

18
Q

NPCA
AJCC Staging

Identify the Prognostic Group

T2, N1, M0

A

Stage II

T0-1, N0-1
T2, N0-1

19
Q

NPCA

What is the preferred treatment for Stage I disease?

A

RT alone

20
Q

NPCA

What is the preferred treatment for Stage II-IVA disease?

A

induction chemo + CCRT
or
CCRT + adjv. chemo

CCRT alone is category 2B

21
Q

NPCA

What is the preferred chemotherapy regimen for CCRT?

A

cisplatin

22
Q

NPCA

What is the preferred drug combination for induction therapy?

A

Cisplatin+Gemcitabine
(cat1)

TPF (cat1 only for non-EBV associated)

23
Q

NPCA

What is the preferred drug combination for adjuvant therapy?

A

PF

24
Q

NPCA

Where is the most common origin of NPCA?

A

lateral walls (incl. fossa of Rosenmüller)

25
Q

NPCA

Boundaries of the nasopharynx.
Anterior

A

continuous with the nasal cavity, via the posterior choanae

26
Q

NPCA

Boundaries of the nasopharynx.
inferior

A

communicates with the oropharynx

27
Q

NPCA

Boundaries of the nasopharynx.
Roof

A

basilar portion of sphenoid and occipital bones

28
Q

NPCA

Boundaries of the nasopharynx.
Floor

A

superior surface of the soft palata and nasopharyngeal isthmus

29
Q

NPCA

Boundaries of the nasopharynx.
lateral walls

A

Eustachian tube bounded by the torus tubarius

30
Q

NPCA

Boundaries of the nasopharynx.
contents of the posterior wall

A

pharyngeal constrictors
pharyngobasilar fascia
buccopharyngeal fascia