Notes pages 3 & 4

Question 1

Narcotic Analgesics examples

Answer 1

Morphine
Hydrocodone
Codeine
Oxycontin

Question 2

Narcotic Analgesics depress the ___ which leads to depressed __ __

Answer 2

CNS

Central reflexes

Question 3

Narcotic Analgesics stimulates the __ n. and ___ center –> Sinus __ and “___ ___”

Answer 3

Vagus
Vomiting
Bradycardia
Projectile vomiting

Question 4

Narcotic Analgesics suppress the __ center and __ reflex

Answer 4

respiratory

cough

Question 5

Narcotic Analgesics cause spastic __ of GI tract.

Answer 5

Paralysis

Question 6

Narcotic Analgesics stimulate the __-__ nucleus in the pretectal region of the brain to increase activity in CN __ PNS fibers –> Sphincter mm. of __ contract –> Pin point pupil

Answer 6

Edinger- Westphal
III
Iris

Question 7

Non-Narcotic Analgesics: Most important is __ in __

Answer 7

Acetaminophen

Tylenol

Question 8

Non-Narcotic Analgesics Inhibit __ synthesis in the __ to cause relief from pain and fever

Answer 8

prostaglandin

brain

Question 9

Acute overdose of Non-Narcotic Analgesics causes ___ ___ ___

Answer 9

Centrilobular Hepatic Necrosis

Question 10

Chronic use of Non-narcotic Analgesics can cause __ __

Answer 10

kidney failure

Question 11

MAO Inhibitor Example

Answer 11

Tranylcypromine

Question 12

MAO Inhibitors are used as __ __

Answer 12

Anti-Depressants

Question 13

MAO Inhibitors increase activity at ____ synapses

Answer 13

Aminergic (NE, Serotonin)

Question 14

MAO inhibitors can cause ___ crisis when combined with ___ foods –> ___

Answer 14

hypertensive
Fermented
Stroke

Question 15

Tricyclic Antidepressants example

Answer 15

Imipramine

Question 16

Tricyclic Antidepressants prolong __ interval on the ECG

Answer 16

QT

Question 17

Tricyclic Antidepressantshave potent anti-___ adverse effects ( Block __ __ receptors in smooth muscle, exocrine glands, and SA node) –> Flaccid Intestinal stasis, pupil ___, sphincter muscles of iris relax from loss of PSNS input , decreased secretions, dy mucous membranes in nose and mouth. Difficulty chewing food and swallowing, eye irritation- no tears, hyperthermia- no sweat.

Answer 17

Cholinergic
muscarinic ACh
Dilation

Question 18

SSRI examples

Answer 18

Prozac
Zoloft
“Serotonin Syndrome”

Question 19

Ethylene Glycol AKA

Answer 19

Antifreeze

Question 20

Ethylene Glycol causes ___ depression like ethyl alcohol

Answer 20

CNS

Question 21

Ethylene Glycol forms __ acid in the __ –> ___ –> ___ myocardial contractility; __ peristalsis

Answer 21

Oxalic
Liver
Hypocalcemia
Decreaed
Decreased

Question 22

Ethylene Glycol causes __ __ formation in soft tissue

Answer 22

Calcium Oxalate

Question 23

Ethylene Glycol ingestion is TX with titrated doses of __ __ which is a prefered substrate for the enzymes.

Answer 23

Ethyl Alcohol

Question 24

Methyl Alcohol Examples

Answer 24

Methanol

Woos Spirit

Question 25

Methyl Alcohol is used as a __ and as a __ __

Answer 25

solvent

de icer

Question 26

Methly alcohol forms ___ and then ___ (same enzymes as anti-freeze)

Answer 26

Formaldehyde

Formate

Question 27

Formate Enzyme destroys __ cells in the ___ –> ___

Answer 27

ganglion
retina
blindness

Question 28

Methyl Alcohol ingestion is Tx by giving triated doses of ___ ___ which is the prefered substrate for enzymes.

Answer 28

Ethyl Alcohol