Final TQ

Question 1

Initial effect of inhaling CO

Answer 1

Headache

Question 2

Chronic use of steroidal anti-inflamatory meds will cause what 3 effects?

Answer 2

Ulcers
Hyperglycemia
Cataracts

Question 3

What does NO do?

Answer 3

Oxidizes Hb to form methemoglobin

Question 4

Aspirin should not be used to manage what?

Answer 4

Gouty Arthritis

Question 5

Chronic steroidal anti-inflammatory use can cause GI ulcers because of inhibition of which enzyme?

Answer 5

Phospholipase A2

Question 6

Effects of CO inhalation

Answer 6

• reduces Hb available to transport O2
• mis-Dx as flu
• can cause fetal damage

Question 7

Air pollutants wcause which symptom?

Answer 7

Pulmonary edema

Question 8

Whats happens with dermal contact with a strong acid (HCl)

Answer 8

Superficial damage with eschar formation

Question 9

Hypertensive crisis is a serious adverse interaction involving which substances?

Answer 9

Monoamine Oxidase Inhibitors

Question 10

Delayed-onset pulmonary toxicity is characteristic of which chemical exposure?

Answer 10

Inhalation of irritant gas with low water solubility

Question 11

Methemoglobinemia is characterized by what?

Answer 11

Caused by exposure to oxidizing chemicals

Question 12

Person using corticosteroids for OA over a chronic duration will have hyperglycemia due to what reason?

Answer 12

Stimulation of GNG

Question 13

Exposure to organophosphate insecticide (ACh transferase inhibitor) will cause what effect?

Answer 13

increased exocrine secretions

Question 14

CO has the greatest binding affinity for which Hb?

Answer 14

Fetal Hb

Question 15

Mad Hatter’s Dz is a consequence of chronic exposure to what?

Answer 15

Mercury

Question 16

Risk for Parkinson’s and angina is increased upon exposure to what?

Answer 16

CO

Question 17

Daily use of low doses of aspirin is prescribed to pts to prevent intra-vascular clotting after CV surgery. What is the rationale?

Answer 17

Inhibits thromboxane synthetase

Question 18

Cheyne-Stokes resiration is caused by fluctuations in PCO2 level. This is a characteristic effect of what?

Answer 18

Narcotic analgesic ovedose

Question 19

Chronic use of what therapeutic agent is most liley to increase risk for fx and osteoporosis

Answer 19

Proton pump inhibitor

Question 20

NO must be combined w/ adequate O2 when used to perform denatl procedures in order to prevent what?

Answer 20

Methemoglobinemia

Question 21

CO does NOT cause which effect?

Answer 21

Coughing

Question 22

Highly soluble irritant gases pose the highest risk for adverse effects in pts. with what condition?

Answer 22

Asthma

Question 23

The best confirmation of CO poising is what?

Answer 23

Carboxymethemoglobin blood levels

Question 24

What toxic chemical has a sweet taste?

Answer 24

Lead acetate

Question 25

What category of chemicals will cause liquefactive necrosis upon contact with living tissues?

Answer 25

Strong bases

Question 26

Excessive consumption of what food item will increase risk for mercury poisoning?

Answer 26

Bigeye tuna

Question 27

What poison causes psychosis?

Answer 27

mercury

Question 28

non-steroida anti-inflammatory meds. provide palliative relief by inhibiting what enzyme?

Answer 28

Cyclo-oxygenase

Question 29

Acute overdose w/ aspiring can cause hyperthermia. Why does this occur?

Answer 29

Aspirin uncouples Ox-Phos

Question 30

Even low dose use of aspirin on chronic basis can increas risk for GI ulcers b/c why?

Answer 30

Aspirin inhibits Cox 1 in teh gastric mucosa

Question 31

Which is Not an anti-inflammatory steroid?

Answer 31

Testosterone *Cortisol, prednisone, and Dexamethasone are inflammatory

Question 32

Acute overdose w/ what produces centrilobular hepatic necrosis?

Answer 32

tylenol

Question 33

Associated with Reyes syndrome

Answer 33

Aspirin

Question 34

Causes Hyperglycemia through Glycogenolysis

Answer 34

Epinephrine

Question 35

Stimulate GNG

Answer 35

Prednisone

Question 36

Used to manage viral fevers in children

Answer 36

Tylenol

Question 37

Causes Hypoglycemic coma

Answer 37

Insulin

Question 38

Can cause toxic effects during rapid weight loss

Answer 38

Lipophilic chemicals

Question 39

Can increase bio-inactivation by liver enzymes

Answer 39

Smoking

Question 40

Can increase toxicity due to therapeutic doses of any chemical

Answer 40

Inadequate H2O intake/ dehydration

Question 41

Overdoses can cause cardiac palpitations

Answer 41

Synthroid

Question 42

Therapeutic use can cause hyperglycemia

Answer 42

Hydrocortisone