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Tox > Final TQ > Flashcards

Final TQ Flashcards

1
Q

Initial effect of inhaling CO

A

Headache

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2
Q

Chronic use of steroidal anti-inflamatory meds will cause what 3 effects?

A

Ulcers
Hyperglycemia
Cataracts

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3
Q

What does NO do?

A

Oxidizes Hb to form methemoglobin

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4
Q

Aspirin should not be used to manage what?

A

Gouty Arthritis

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5
Q

Chronic steroidal anti-inflammatory use can cause GI ulcers because of inhibition of which enzyme?

A

Phospholipase A2

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6
Q

Effects of CO inhalation

A
  • reduces Hb available to transport O2
  • mis-Dx as flu
  • can cause fetal damage
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7
Q

Air pollutants wcause which symptom?

A

Pulmonary edema

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8
Q

Whats happens with dermal contact with a strong acid (HCl)

A

Superficial damage with eschar formation

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9
Q

Hypertensive crisis is a serious adverse interaction involving which substances?

A

Monoamine Oxidase Inhibitors

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10
Q

Delayed-onset pulmonary toxicity is characteristic of which chemical exposure?

A

Inhalation of irritant gas with low water solubility

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11
Q

Methemoglobinemia is characterized by what?

A

Caused by exposure to oxidizing chemicals

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12
Q

Person using corticosteroids for OA over a chronic duration will have hyperglycemia due to what reason?

A

Stimulation of GNG

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13
Q

Exposure to organophosphate insecticide (ACh transferase inhibitor) will cause what effect?

A

increased exocrine secretions

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14
Q

CO has the greatest binding affinity for which Hb?

A

Fetal Hb

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15
Q

Mad Hatter’s Dz is a consequence of chronic exposure to what?

A

Mercury

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16
Q

Risk for Parkinson’s and angina is increased upon exposure to what?

A

CO

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17
Q

Daily use of low doses of aspirin is prescribed to pts to prevent intra-vascular clotting after CV surgery. What is the rationale?

A

Inhibits thromboxane synthetase

18
Q

Cheyne-Stokes resiration is caused by fluctuations in PCO2 level. This is a characteristic effect of what?

A

Narcotic analgesic ovedose

19
Q

Chronic use of what therapeutic agent is most liley to increase risk for fx and osteoporosis

A

Proton pump inhibitor

20
Q

NO must be combined w/ adequate O2 when used to perform denatl procedures in order to prevent what?

A

Methemoglobinemia

21
Q

CO does NOT cause which effect?

A

Coughing

22
Q

Highly soluble irritant gases pose the highest risk for adverse effects in pts. with what condition?

A

Asthma

23
Q

The best confirmation of CO poising is what?

A

Carboxymethemoglobin blood levels

24
Q

What toxic chemical has a sweet taste?

A

Lead acetate

25
Q

What category of chemicals will cause liquefactive necrosis upon contact with living tissues?

A

Strong bases

26
Q

Excessive consumption of what food item will increase risk for mercury poisoning?

A

Bigeye tuna

27
Q

What poison causes psychosis?

A

mercury

28
Q

non-steroida anti-inflammatory meds. provide palliative relief by inhibiting what enzyme?

A

Cyclo-oxygenase

29
Q

Acute overdose w/ aspiring can cause hyperthermia. Why does this occur?

A

Aspirin uncouples Ox-Phos

30
Q

Even low dose use of aspirin on chronic basis can increas risk for GI ulcers b/c why?

A

Aspirin inhibits Cox 1 in teh gastric mucosa

31
Q

Which is Not an anti-inflammatory steroid?

A

Testosterone

*Cortisol, prednisone, and Dexamethasone are inflammatory

32
Q

Acute overdose w/ what produces centrilobular hepatic necrosis?

A

tylenol

33
Q

Associated with Reyes syndrome

A

Aspirin

34
Q

Causes Hyperglycemia through Glycogenolysis

A

Epinephrine

35
Q

Stimulate GNG

A

Prednisone

36
Q

Used to manage viral fevers in children

A

Tylenol

37
Q

Causes Hypoglycemic coma

A

Insulin

38
Q

Can cause toxic effects during rapid weight loss

A

Lipophilic chemicals

39
Q

Can increase bio-inactivation by liver enzymes

A

Smoking

40
Q

Can increase toxicity due to therapeutic doses of any chemical

A

Inadequate H2O intake/ dehydration

41
Q

Overdoses can cause cardiac palpitations

A

Synthroid

42
Q

Therapeutic use can cause hyperglycemia

A

Hydrocortisone

Tox (3 decks)

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