Note Cards Flashcards
Meds that cause reflex bradycardia
Phenylephrine
Dopamine
Drugs that are Racemix Mixtures
Dobutamine Verapamil Sotalol Mepivacaine Bupivacaine
+/- isotomiers of Dobutamine
(-) potent alpha agonist; weak beta agonist
(+) competative agonist at alpha; potent Beta agonist
+/- isotomiers of Verapamil
(-) reason CCB classification
(+) Na-channels –> LA effect
+/- isotomiers of Sotalol
(-) beta blocker (+) class III
(+) S of bupivacaine
less toxic than that of mepivacaine?
Drugs to avoid with LHF
“CBL”
- CCB (verapamil)
- Beta blockers
- left sided HF
Drugs to avoid in RHF
“DNR”
- Dopamine
- Norepi
- right sided HF
Drugs that have Tachyphylaxis
- Dobutamine (beta)
- Ephedrine ( alpha inhibition p first dose)
- NTG – more of a tolerance
Drugs it’s important to HYDRATE before administering :
- Phenoxybenzamine
- CCB’s
- BB’s
Drugs known to cause ORTHOSTATIC hypotension
- Phenoxybenzamine
- Prazosin
- Labetalol
Prodrugs:
- SNP
- Enalipril
- Lovastatin
- Simvastatin
- ASA
- Clopidegrel (Plavix)
- Parsurgrel (effient)
- T4 to T3
- Fenofibrate?
Drugs to decrease w/Liver dx
- cardizem
- Labetalol
Interactions with volitiles:
Yohimbine (alpha 2)
Interactions with NMBD:
CCB - decrease AcH at presynaptic cleft
Interactions with LA:
Verapamil
Diltaizem
Increase IOP:
Dopamine
Versed?
Fenoldopam
Succ
DUMBELLS
For Cholinergics – “Wet”
what increases ACh but is breaking on the heart?
cholinergics
Anti-Cholinergics (antimuscarinics) are:
- atropine
- Scopolamine
- glycopyrrolate
- Ipartropium
- Oxybutinin
Protein binding Greatest to least - Beta Blockers:
“-PENAMA”
- Propranolol
- Esmolol
- Nadolol
- Acebutolol
- Metoprolol
- Atenolol
Vd of Opioids greatest to least:
“FMMSRA”
- Fentanyl
- Meperidine
- Morphine
- Sufentanil
- Remifentanil
- Alfentanil
Protein binding (greatest to least) - LA:
“LBRMTLPPC”
- Levo
- Bupivacaine
- Ropivacaine
- Mepivacaine
- Tetracaine
- Lidocaine
- Prilocaine
- Chloroprocaine (zero)
LA Metabolism fastest to slowest (esters)
“PLEB”
- Prilocaine
- Lidocaine/Mepivacaine
- Etiocaine
- Bupivacaine/Ropivacaine
RPM - “start slow and speed up”
Ropiviacaine, Prilocaine = Metabolism
Protein binding of antiarrhymics (greatest to least)
- Amiodarone
- Propranolol
- Verapamil
- Quinidine
- Lidocaine
- Procainanide
- Sotalol (zero)
Gases - hepatic effects greatest to least:
“HEIDes”
H > E> I > Des
NMB’s in order of R/O anaphylaxis (greatest to least)
-Succ> Atracurium >Cis > Roc > Vec
Gases that potentiate NMB (most to least)
Des > Sevo > Halo > N2O
Order of NMD’s Sugammadex works on (best to least):
Roc > Vanc»_space; Panc
CO equation =
CO = SV x HR
Ficks Principle Equation
CO = [ O2 consumption / (O2 pulm vein) - (O2 pulm artery) ]
SV =
EDV - ESV
SV alternative (CO and HR)
SV = CO/HR
EF =
SV/EDV
SVR =
[ (MAP - CVP) / CO] x 80