not inc Flashcards
what equation gives the rate of dissolution
modified Noyes-Whitney equation
Cs represents
the solubility of the drug in the solvent
USP dissolution systems aim to find what value?
k value – dissolution rate constant
in fick’s first law, k represents the partition coefficient.
if K is zero, what does this mean?
NO PERMEABILITY
If Cs is high….
high permeability and high bioavailability
for most oral drugs, absorption is via what mechanism?
first order
concentration dependent
albumin is a ____
lyophilic colloidal
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