Normal pressure hydrocephalus Flashcards

1
Q

Normal pressure hydrocephalus (NPH) is an abnormal buildup of cerebrospinal fluid (CSF) in the brain’s ventricles (cavities). What is the incidence of NPH?

1 - 600 cases per 100,000
2 - 60 cases per 100,000
3 - 6 cases per 100,000
4 - 0.6 cases per 100,000

A

3 - 6 cases per 100,000

Affects men and women equally

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2
Q

Normal pressure hydrocephalus (NPH) is an abnormal buildup of cerebrospinal fluid (CSF) in the brain’s ventricles (cavities). What age does the prevalence of NPH peak at?

1 - 20-30
2 - 30-40
3 - 40-50
4 - 60-70

A

4 - 60-70

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3
Q

What is thought to be the cause of Normal pressure hydrocephalus (NPH)?

1 - increase CSF production
2 - reduced CSF absorption
3 - narrowing of ventricles
4 - narrowing of the foreman magnum

A

2 - reduced CSF absorption

Ventricles become enlarged

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4
Q

Patients with normal pressure hydrocephalus (NPH) can present with all of the following EXCEPT which one?

1 - urinary incontinence
2 - dementia and bradyphrenia
3 - gait abnormality (may be similar to Parkinson’s disease)
4 - respiratory depression

A

4 - respiratory depression

3 Ws:
- water/wetting
- wacky
- wobbly

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5
Q

Is normal pressure hydrocephalus (NPH) always idiopathic?

A
  • no

Can occur following head trauma
- May present months after trauma

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6
Q

How is normal pressure hydrocephalus (NPH) diagnosed?

1 - invasive catheter measurement of intracranial pressure
2 - urine diary
3 - renal function
4 - head CT/MRI

A

4 - head CT/MRI

  • enlarged ventricles
  • no major sulcus atrophy
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7
Q

Which ventricle is typically enlarged the most in normal pressure hydrocephalus (NPH)?

1 - lateral ventricles
2 - 4th ventricle
3 - 3rd ventricle
4 - cerebral aqueduct

A

2 - 4th ventricle

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8
Q

What is the definitive treatment for normal pressure hydrocephalus (NPH)?

1 - ventriculoperitoneal shunting
2 - mannitol
3 - repeated spinal taps
4 - furosemide

A

1 - ventriculoperitoneal shunting

10% of patients who have shunts experience significant complications such as seizures, infection and intracerebral haemorrhages

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