Normal Microbiota and Nosocomial Infections Flashcards
What does a commensalism mean?
Organsisms living together, sharing nutrients; Co-existing
What are normal/indigenous microbiota?
Microbes found in healthy people; Not in the process of causing disease.
Define Transient flora
Present in some healthy people for a short time, without causing disease and is eventually cleared.
Define carriage
Asymptomatic; Colonized with pathogen but no disease symptoms can transmit to others.
Define Persistence/Latency
Pathogen remains in body following disease, but symptoms may reactivate later to produce symptoms
What are the benefits of Normal Microbiota?
Development and priming of the immune system, Production of vitamins and essential nutrients, and competing with pathogens.
How does normal microbiota help develop the immune system?
Low levels of antibody against normal flora can prevent disease should the organism enter another site where it could cause a disease.
What are the dangers of the normal microbiota?
Opportunistic infection.
Describe a newborns microbiota.
Their guts are sterile at birth but colonized soon after birth; Composition of microbiota changes with geography, diet, age, hormonal state, and physiologic differences.
Name the resident microbes of the skin.
Staphylococcus, Proprionibacterium, Acinetobacter
Are gram - cells on the skin?
Not many; Too dry for them to thrive.
Name the resident microbe of the eyes and ears.
Coagulase negative staphylococci
Whats common in the external nares?
Strep, Coagulae negative staph
Whats common in the naso/oropharynx?
Staphylococci, Veillonella, Acinetobacter
Which bacteria can live in the stomach?
Heliobacter; Can cause ulcers
