Normal Aging Flashcards
when do the major developmental changes occur?
first 3 years of life
when does a modest increase in brain weight occur?
3-18 years
myelination of new cortical areas continues into
4th decade
gross anatomical change: brain weight
- plateus at 18
- slowly declines by age 50
gross anatomical changes: ventricles
- increased in size found between 3rd and 7th decade
- more rapid thereafter
gross anatomical changes: cortical atrophy
- gyri appear thinner, sulci widen
- no correlation with amount of ventricular dilation
microscopic changes
- neuronal dropout
- lipofuscin accumulation
- granulovascular degeneration
- neurofibrillary tangles
- neuritic (senile) plaques
microscopic changes: neuronal dropout
significant loss of neurons in superior temporal gyrus, precentral gyrus, and striate cortex
microscopic changes: lipofuscin accumulation
- yellow-brown pigment (lipid and protein) accumulates in the cytoplasm of neurons
- increases with chronological age
- healthy diet helps prevent this
microscopic changes: granulovascular degeneration
small, clear vacuoles with a smaller central granule (often found in the hippocampus)
the hippocampus helps with
memory
microscopic changes: neurofibrillary tangles
- Alzheimer’s disease
- thick, fibrous brand arranged irregularly in the cytoplasm of neurons
microscopic changes: neuritic (senile) plaques
found in neuronal processes and supporting cells
psychological aspects of aging
- fluid intelligence
- crystalized intelligence
- practical intelligence
fluid intelligence
- general cognitive capacity within the individual that requires relational thinking
- ability to develop creative solutions to problems
crystalized intelligence
- acculturated skills that are cumulative
- ability to understand concepts based on prior learning
- knowledge gained by experience
example of crystalized intelligence
playing wordle and knowing that /t/ and /k/ can go in front of /r/
practical intelligence
ability to apply intellectual skills to everyday activities
adult cognitive changes
- fluid intelligence
- crystalized intelligence
- practical intelligence
- non-verbal intelligence
adult cognitive changes: fluid intelligence
- decreases with age, rigidity
- abilities such as inductive reasoning, figural relations, associative memory