Normal/Abnormal Cavity Development - Severson Flashcards
What body cavities develop from the intraembryonic coelom?
- Pericardial cavity
- Pleural cavity
- Peritoneal cavity
What part of the lateral plate mesoderm forms the parietal layer of the serous cavity?
Somatic mesoderm
What part of the lateral plate mesoderm forms the visceral layer of the serous cavity?
Splanchnic mesoderm
What developmental malformation do ectopia cordis, congenital umbilical hernia, gastroschisis, and exstrophy of the bladder have in common?
Lateral folding errors
How does the primitive pericardial cavity reach the cardiac region of the thorax?
Cephalic-caudal folding
What are the pericardioperitoneal canals?
two tubes that connect the pericardial and peritoneal cavities on each side of the foregut
***becomes the Pleural Cavity
What is the function of the dorsal mesentary?
- Carry motor branches of the Phrenic Nerve
- Form two muscular bands = R/L crura of the diaphragm
What is the purpose of the pleuropericardial membranes?
- Divide the thoracic cavity into a Pericardial cavity and two Pleural cavities
- by fusing with eachother at the root of the lungs
- Contain the Common Cardinal Veins and the Phrenic nerves
- Forms the Fibrous pericardium
What is the purpose of the pleuroperitoneal membranes?
- Close the caudal end of the pericardioperitoneal canal
- Separate the Pleural cavities from the Peritoneal cavity
What adult structure do the pleuropericardial membranes form?
Fibrous Pericardium
What are the four developmental components that contribute to the diaphragm?
- Transverse septum
- Pleuroperitoneal membranes
- Dorsal mesentery of the esophagus
- Lateral and dorsal body walls
What cervical nerves innervate the major muscle mass of the diaphragm?
Cervical Nerves 3, 4, and 5
(become phrenic nerve)
What nerves contribute to the sensory innervation of the diaphragm?
- Sensory fibers of the Phrenic nerve supply all of the diaphragm
- EXCEPT: the costal margin, which receives sensory innervation from lower intercostal nerves
Why is the Phrenic Nerve associated with the fibrous pericardium in the adult?
The Phrenic Nerve passes through the Pleuropericardial Fold which later becomes the Fibrous Pericardium.
What fails to occur when a congenital diaphragmatic hernia develops?
Fusion of the Pleuroperitoneal membranes with the other diaphragmatic components
Why may polyhydramnios be present with a congenital diaphragmatic hernia?
***
(polyhydramnios = excess amniotic fluid)
Why does herniation of abdominal viscera usually occur on the left side?
Defect is usually unilateral and on the left side because the left Pericardioperitoneal canal is larger than the right and closes later.
What happens to the thoracic viscera with a congenital diaphragmatic hernia?
displaced to the right
What is the difference between a congenital diaphragmatic hernia (CDH) and eventration of diaphragm?
- CDH - diaphragm does not completely fuse/form
- Eventration - diaphragm fuses completely, but half of diaphragm has defective musculature
Where do congenital esophageal hiatal and retrosternal hernias occur?
- Hiatal
- herniation of stomach through esophageal hiatus
- Retrosternal
- herniation between sternum/ribs and the diaphragm