nondisjunctin Flashcards
What is non-disjunction?
Non-disjunction is the failure of homologous chromosomes or sister chromatids to separate properly during cell division.
True or False: Non-disjunction can occur during both meiosis and mitosis.
True
Fill in the blank: Non-disjunction often leads to __________.
aneuploidy
What is aneuploidy?
Aneuploidy is a condition in which there is an abnormal number of chromosomes in a cell.
Which chromosome abnormality is commonly associated with Down syndrome?
Trisomy 21
Multiple Choice: What is the most common cause of Down syndrome?
A. Non-disjunction during maternal meiosis
True or False: Non-disjunction can lead to conditions such as Turner syndrome.
True
What is Turner syndrome?
Turner syndrome is a condition caused by the absence of one X chromosome in females, leading to a total of 45 chromosomes.
Fill in the blank: Non-disjunction can result in __________ gametes.
abnormal
Short Answer: Name one method used to detect non-disjunction in humans.
Karyotyping
Multiple Choice: Which phase of meiosis is most commonly associated with non-disjunction?
B. Anaphase I
True or False: Non-disjunction can occur in both meiosis I and meiosis II.
True
What is the result of non-disjunction during meiosis I?
It results in two gametes with an extra chromosome and two with one less chromosome.
Fill in the blank: Non-disjunction can lead to __________ in offspring.
genetic disorders