nondisjunctin

Question 2

What is non-disjunction?

Answer 2

Non-disjunction is the failure of homologous chromosomes or sister chromatids to separate properly during cell division.

Question 3

True or False: Non-disjunction can occur during both meiosis and mitosis.

Answer 3

True

Question 4

Fill in the blank: Non-disjunction often leads to __________.

Answer 4

aneuploidy

Question 5

What is aneuploidy?

Answer 5

Aneuploidy is a condition in which there is an abnormal number of chromosomes in a cell.

Question 6

Which chromosome abnormality is commonly associated with Down syndrome?

Answer 6

Trisomy 21

Question 7

Multiple Choice: What is the most common cause of Down syndrome?

Answer 7

A. Non-disjunction during maternal meiosis

Question 8

True or False: Non-disjunction can lead to conditions such as Turner syndrome.

Answer 8

True

Question 9

What is Turner syndrome?

Answer 9

Turner syndrome is a condition caused by the absence of one X chromosome in females, leading to a total of 45 chromosomes.

Question 10

Fill in the blank: Non-disjunction can result in __________ gametes.

Answer 10

abnormal

Question 11

Short Answer: Name one method used to detect non-disjunction in humans.

Answer 11

Karyotyping

Question 12

Multiple Choice: Which phase of meiosis is most commonly associated with non-disjunction?

Answer 12

B. Anaphase I

Question 13

True or False: Non-disjunction can occur in both meiosis I and meiosis II.

Answer 13

True

Question 14

What is the result of non-disjunction during meiosis I?

Answer 14

It results in two gametes with an extra chromosome and two with one less chromosome.

Question 15

Fill in the blank: Non-disjunction can lead to __________ in offspring.

Answer 15

genetic disorders

Question 16

Short Answer: What is the typical chromosome number in a human zygote?

Answer 16

46 chromosomes

Question 17

Multiple Choice: Which of the following is a potential outcome of non-disjunction?

Answer 17

C. Klinefelter syndrome

Question 18

True or False: Non-disjunction only occurs in females.

Answer 18

False

Question 19

What is Klinefelter syndrome?

Answer 19

Klinefelter syndrome is a condition in males caused by the presence of an extra X chromosome, resulting in a total of 47 chromosomes.

Question 20

Fill in the blank: The risk of non-disjunction increases with __________.

Answer 20

maternal age

Question 21

Short Answer: What genetic testing can confirm non-disjunction-related conditions?

Answer 21

Amniocentesis or chorionic villus sampling (CVS)

Question 22

Multiple Choice: Non-disjunction can lead to which of the following?

Answer 22

A. Trisomy

Question 23

True or False: Non-disjunction is a rare event in cell division.

Answer 23

False

Question 24

What is the role of spindle fibers in cell division?

Answer 24

Spindle fibers help separate chromosomes during cell division.

Question 25

Fill in the blank: Non-disjunction can occur due to improper __________ of spindle fibers.

Answer 25

attachment

Question 26

Short Answer: What is the consequence of non-disjunction in meiosis II?

Answer 26

It results in two normal gametes and two abnormal gametes.

Question 27

Multiple Choice: Which of the following is NOT a result of non-disjunction?

Answer 27

D. Normal chromosome number