Non statin Add on

Question 1

What add on with statins

Answer 1

ezetimibe or PCSK9 inhibitor

Question 2

Ezetimibe MOA

Answer 2

inhibit absorption of cholesterol in small intestines

Question 3

Ezetimibe

Answer 3

zetia

Question 4

ezetimibe dosing

Answer 4

10mg QD

Question 5

Side effects of ezetimibe

Answer 5

myalgias
diarrhea
Upper respiratory tract infections
arthralgias
sinusitis
pain in extremities

Question 6

When should ezetimibe be given when taking bile acid sequestrants

Answer 6

2hr before or 4 hrs after

Question 7

What happens when ezetimibe and cyclosporine are given together

Answer 7

both concetrations can be increased
monitor cyclosporine levels

Question 8

What should not be used with ezetimibe

Answer 8

gemfibrozil

Question 9

What happens when ezetimibe and fibrates are used together

Answer 9

increase risk of choleithiasis

Question 10

PCSK9 inhibitors

Answer 10

Alrocumab
evolocumab

Question 11

Alrocumab

Answer 11

praluent

Question 12

evolocumab

Answer 12

repatha

Question 13

Praluent dosing ASCVD

Answer 13

75-150 q2wks

Question 14

Repatha dosing ASCVD

Answer 14

140 mg q2wks
420 every month

Question 15

Repatha dosing hypocholestremia

Answer 15

420 every month