Bile acid seqestrants

Question 1

Cholestryamine

Answer 1

Questran
Prevalite

Question 2

Colesvelam

Answer 2

Welchol

Question 3

Colestipol

Answer 3

Colestid

Question 4

Questran dosing

Answer 4

Initial 4g QD or BID
Maintenance 8-16g divided BID w/meals

Question 5

Questran MAX dose

Answer 5

24g QD

Question 6

Bile acid sequestrant MOA

Answer 6

bind to bile acid in intestines excreted in feces

Question 7

Contraindication Cholestyramine

Answer 7

complete biliary obstruction

Question 8

Contraindication Colesevelam

Answer 8

bowel obstruction
TG > 500
hx of hypertriglyceridemia induced pancreatitis

Question 9

Warning Cholestyramine

Answer 9

increased bleeding due to Vit k deficiency

Question 10

Side effects bile acid sequestrants

Answer 10

constipation
abdominal pain
cramping
bloating
gas
increased TG

Question 11

Lipid effect of bile acid sequestrants

Answer 11

lower LDL
increase TG

Question 12

When should other drugs be given when taking bile acid sequestrants

Answer 12

1-4 hrs before
4-6 hrs after

Question 13

How do bile acid sequestrants affect vitamins

Answer 13

decrease absorption of fat soluble vitamins folate and iron