Non-spore forming anaerobes Flashcards
What are the anaerobic gram positive cocci?
Finegoldia, Micromonas, Peptostreptococcus.
What are the anaerobic gram positive rods?
Actinomyces, Propionibacterium, Lactobacillus, and Bifidobacterium
What are the anaerobic gram negative cocci?
Veillona
What are the anaerobic gram negative rods?
Bacteroides, Fusobacterium, Porphyromonas, and Prevotella
What antibiotics are the anaerobic gram positive cocci susceptible to?
Penicillins and carbapenems.
What antibiotics are the non spore forming anaerobes generally resistant to?
Aminoglycosides.
What diseases do the gram positive cocci usually cause?
They most often cause chronic sinusitis, but can cause acute sinusitis if coming from a peridontal disease.
What is the predominant disease causing anaerobic gram positive cocci?
Peptostreptococcus.
What diseases are associated with Peptostreptococcus?
Respiratory infections such as chronic sinusitis, mastoiditis, lung abscesses, aspiration pneumonia, and acute and chronic ottis media. Additionally, they cause necrotizing, subcutaneous, and soft tissue infections.
Why is Finegoldia magna an up and coming pathogen?
It possesses virulence factors similar to those found in S. pyogenes and S. aureus.
Where are you more likely to find Finegoldia magna infections?
In a hospital setting.
What are the biochemical markers for Proprionibacterium acne?
Indole positive gram positive rod.
What are the biochemical markers for Actinomyces?
Indole negative, Nitrate test positive, catalase negative gram positive rods.
What disease do Actinomyce spp cause?
Actinomycosis. It resents mostly cervicofacial, but can also be thoracic, abdominal, pelvic, and CNS.
What antibiotics are Actinomyces sensitive to?
Penicillin, carbpenems, macrolides, and clindamycin.
What diseases does Proprionibacterium acnes cause?
Acnes vulgaris and opportunistic infections, particularly of prosthetic devices.
What antibiotics are used for Proprionibacterium acnes?
Erythromycin and clindamycin.
Where are Lactobacillus spp not likely to be found?
In urinary infections, as they cannot grow in urine.
What antibiotic is Lactobacillus resistant to?
Vancomycin
What is the treatment regimen for Lactobacillus infections?
Penicilin and aminoglycoside combination.
What is the only non-spore forming anaerobic gram negative cocci?
Veillona. It is implicated in preventing dental carries by metabolizing acidic by-products into less acidic compounds.
What is the only bile loving organism listed in this lecture?
Bacteroides (Bacteroides fragilis is the most clinically relevant).
What gram negative rod is strongly associated with Chorioamnionitis?
Fusobacterium nucleatum. It appears to play a role in pre-term births.
What is Lemierre syndrome?
When a bacterial throat infection progresses to the posterior pharyngeal space (resulting in peritonsillar abscesses). It then progresses to secondary septic thrombophlebitis of the jugular vein, bacteremia, and frequent spread (most commonly to the lungs).
What is the most common pathogen responsible for Lemierre syndrome?
Fusobacterium necrophorum.
