Non-specific Structures (can be present in Melanocytic/Non-melanocytic Lesions) Flashcards

1
Q

Non-specific dermoscopic structures

A
Dots
Blotch
Peppering/granularity + scar-like depigmentation
Shiny white structures  - 
- streaks
- rosettes
- blotches and strands 
Blue-white veil
Scale
Erosion/ulceration
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2
Q

Dots

A

Black - Aggregates of melanocytes/melanin granules in the upper epidermis

Brown - Aggregates of melanocytes/melanin granules at the DEJ

Blue grey - free pigment in the papillary dermis/inside dermal melanophages vs BCC tumour nests

Naevus, melanoma, BCC, keratinocyte CA

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3
Q

Blotch

A

Hyperpigmentation with abundant melanin throughout epidermis

Naevi (regular centrally located)
Melanoma (multiple, off-centred)
Seborrhoeic keratosis
BCC

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4
Q

Peppering/granularity histopathologic correlate

A

Sign of regression

Free melanin in the papillary dermis/dermal melanophages

Melanoma, LPLK, naevi (if focal)

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5
Q

Scar-like depigmentation

A

Sign of regression

Dermal fibroplasia

Melanoma

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6
Q

Shiny white streak

A

Altered dermal collagen

Spitz naevi
Atypical naevi
Melanoma
LPLK
BCC
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7
Q

Rosettes (bright white four leaf clover)

A

Sun damaged skin

Hyperkeratosis of follicular openings

AK
SCC
Melanoma

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8
Q

Shiny white blotches and strands

A

? Fibrosis of underlying stroma (unclear)

BCC
LPLK
Melanoma

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9
Q

Blue-white veil over raised areas

A

Heavily pigmented melanocytes/melanophages in the dermis
Acanthosis
Compact orthokeratosis

Melanoma
Reed/Spitz naevi
Pyogenic granuloma
BCC
Seborrhoeic keratosis
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10
Q

Scale

A

Hyperkeratosis
Parakeratosis

AK
Porokeratosis
SCC
Inflammatory skin diseases

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11
Q

Erosions/ulceration

A

Erosion = epidermal loss
Multiple —> superficial BCC, SCC, trauma

Ulceration = loss of entire epidermis to depth of papillary dermis
Single —> nodular BCC, melanoma, SCC, trauma

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