Mucosal Melanoma

Question 1

Mucosal sites

Answer 1

Glabrous portion of the lips
Mucosal aspect of the lips
Glabrous portion of male/female genitalia

Question 2

Dermoscopic features of mucosal naevus/melanosis

Answer 2

Dotted/globular pattern
Homogenous pattern
Ring-like pattern
Fish scale-like pattern (variant of ring-like pattern)
Hyphal pattern (parallel, reticular-like)

Question 3

Dermoscopic feature of mucosal melanoma

Answer 3

Homogenous pattern with blue, grey, white colours

Multiple colours and structures distributed in a disorganised manner

Question 4

Histopathologic correlate of dotted/globular pattern

Answer 4

Aggregates of melanin the the upper lamina propria

Question 5

Histopathologic correlate of homogenous pattern

Answer 5

Flattened rete ridges

Acanthosis

Question 6

Histopathologic correlate of ring-like pattern/fish scale-like pattern

Answer 6

Hyperpigmented epithelial cells

Broadened rete ridges which skip the papillae

Question 7

Histopathologic correlate of hyphal pattern

Answer 7

Hyperpigmentation of tip of rete ridges distributed obliquely