Non-operative Management of Lung Cancer Flashcards
What type of lung cancer makes up 85% of lung cancer?
Non-small cell cancer
What are the types of non-small cell lung cancer?
Squamous (30%)
Adenocarcinoma (55%)
Large cell undifferentiated
What type of cancer makes up about 15% of ung cancers?
Small cell cancer - extremely aggressive - doubles in size every 29 days
Where do you normally find squamous and adenocarcinoma cancers?
Squamous - usually more central (usually male, usually smokers)
Adenocarcinoma - more peripheral, usualy in woman
What does stage 4 mean?
Distant metastases
What is the percentage of non-small cell cancer is operable?
maximum of 25%
What are all the therapeutic options for cancer?
Surgery
Radiotherapy (radical/curative or palliative)
Chemotherapy
Combination
Targetted therapies
What determines the therapeutic options?
Tumour type, stage, ECOG performance status, patient wishes and options, aims of therapy (curative or palliative)
NSCLC: What are the scores available for the ECOG performance status measurement?
What is the average 5 year survival for non-small cell lung cancer?
Around 40%
What is meant by adjuvant therapy?
When the cancer has appeared to all have been removed – but it is post operative treatment to ensure all cancer has been removed
Is adjuvant therapy helpful in stage 1 and 2 non-small cell lung cancer?
Detrimental - but some possible benefits if mediastinal nodes (N2 or involved margins)
NSCLC: When does preoperative chemotherapy demonstrate significant survival advantage?
Stage 3 Non small cell lung cancer
What percent of Non small cell lung cancer patients have adbvanced disease?
80% of all patients
What is the dose for stage 3 Non small cell lung cancer radiotherapy?
What is the survival rate for stage 3 non small cel lung cancer?
20%