Non-Neoplastic Salivary Gland Disease Flashcards

1
Q

Which glands are major salivary glands?

A

Parotid
Submandibular
Sublingual

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2
Q

What glads are minor salivary glands?

A

Throughout the mouth e.g on palate and lips

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3
Q

Where is partoid gland and what type of saliva?

A

Preauricular

Serous secretions

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4
Q

How much saliva does parotid contribute?

A

20-40%

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5
Q

What type of saliva does submandibular gland produce?

A

Mixed - mucous and serous

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6
Q

How much saliva does submandibular gland contribute?

A

60-70%

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7
Q

Where is sublingual gland and what type of saliva?

A

Located floor of mouth

Mucous secretion

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8
Q

Which major salivary gland is biggest?

A

Parotid

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9
Q

What saliva do minor salivary glands produce?

A

Mucus

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10
Q

Exception of mucus producing minor salivary gland?

A

Serous gland of von ebner - posterior-lateral of tongue

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11
Q

What are 3 types of non-neoplastic lesions?

A

Developmental
Inflammatory
Obstructive/ trauma

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12
Q

Example of developmental non-neoplastic lesion?

A

Stafne bone cavity

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13
Q

What is stafne bone cavity

A

Heterotropic salivary tissue - push into mandible = indentation

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14
Q

How does starfne bone cavity present?

A

Unilocular, corticated well defined radiolucency at angle of mandible
Always under ID canal

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15
Q

Example inflammatory non-neoplastic disease?

A

Sialodenitis - can be chronic or acute

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16
Q

Example of acute sialodenoitis

A

Bacterial

Viral

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17
Q

Examples chronic sialodenitis?

A

Bacterial
Post-irradiation
Sjogrens

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18
Q

Example of bacterial sialodenitis?

A

Acute parotitis

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19
Q

What is acute parotitis?

A

Ascending infection - travel from mouth into parotid duct then gland
Causes actue swelling and pain
Pus exudes from duct

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20
Q

What cause acute parotitis?

A

Oral bacteria e.g staph aurus

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21
Q

How does recurrent parotitis vary in children and adults?

A

Adults - recurrent to dry mouth

Children - recurrent from childhood

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22
Q

How does recurrent parotitis present in adults?

A
40-60 yrs 
F>M
Unilateral 
Secondary xerostomia : sjogrens, drug-induced, radiattion damage 
Ascending infection
23
Q

How does recurrent parotits present in children?

A
up to 15yrs
M = F
Bilateral
No obvious cause/ predisposing factors
Suddent onset 
Weeks duration w/ periods of quiescence 
Not suppurative
24
Q

How does reccurent parotitis in children present sialogram?

A

Snow storm appearnace

Punctate sialectasis - gradular destruction acinar elements = reduced flow

25
Q

What see in histology of recurrent parotitis?

A

Non-specific
Dilation of epithelial lines salivary ducts w/ prominent fibrosis around duct (replace salivary tissue)
Acini and duct damaged
Blue dots = lymphocytes

26
Q

Most common type of viral sialodenitis?

A

Mumps

27
Q

What causes mumps?

A

Mumps virus = paramyxovirus

28
Q

How does mumps presnet clinically?

A

Acute bilateral parotid swelling
Pain, fever and malaise
Can spread to other glands/organs

29
Q

How long does mumps last?

A

Self limiting 10-14 days

Incubation period 2-3 wweeks

30
Q

Complications of mumops?

A

Orchitis
Meningitis
Oophoritis
Pancreitis

31
Q

What is chronic sialodenitis usually secondary to?

A

Duct obstruction - often due calculi

32
Q

When does radiation sialodentitis occur?

A

Doses over 20Gy
High risk above 30Gy
Severe damage 50Gy

33
Q

What types of acini are most sensitive to radiation?

A

Serous

34
Q

What does radiation sialodenitis cause?

A

Inflammation and fibrosis of glands = loss of function

35
Q

What is salivary calculi?

A

Accumulation of calcium and phosphate salts which deposit in salivary duct/ gland

36
Q

Where is most common gland for salivary calculi?

A

Submandibular gland

37
Q

Why is most common gland for calculi submandibular gland?

A

Only major gland pushing saliva up against gravity - ascending duct
Duct - bend (mylohyoid) can cause obstruction

38
Q

How does salivary calculus present on radiograph?

A

Opaque

39
Q

What does obstruction of calculi cause?

A

Obstruction –> saliva retnetion –> inflammation –> fibrosis –> loss of function –> further swelling and fibrosis

40
Q

What see histology of salivary calculi?

A

Fibrosis and inflammation
Destruction of architecture
Loss acini

41
Q

Examples of non-neoplastic disease caused by obstruction/ trauma?

A

Salivary calculi
Mucous cysts
Necrotising sialometaplasia

42
Q

Types of mucoceles?

A

Mucous retention

Mucous extravasation

43
Q

Where is most common site of mucocele?

A

Lower tip - most common site for trauma

44
Q

How do mucoceles present?

A

Usually in children

Painless swellings - rupture and recur

45
Q

What is most common mucoele?

A

Mucous extravasation

46
Q

What is mucous extravasation cyst?

A

Caused by ruptured duct - mucous spills into adjacent connective tissue

47
Q

Histology of mucous extravasation cyst?

A

Lining of fibrous and granulation tissue
Lumen of cyst filled w/ mucous
Macrophage filled with mucous
No epithelial lining

48
Q

Where is most common to see mucous retention cyst?

A

Floor of mouth/ buccal mucosa

Often older age groups

49
Q

What cause mucous retention cyst?

A

Blocked duct - collection mucous

No ruptured duct

50
Q

What see histology mucous retention cyst?

A

Blocked duct - duct dilation
Lumen filled with mucous
Lined w/ ductal epithelium
Cyst wall - fibrous tissue w/ glands

51
Q

What is a ranula?

A

Mucocele in the floor of the mouth - arise from sublingual gland

52
Q

How does necrotising sialometaplasia present?

A

Indurated, ulcerated swelling, often on palate - often mistaken for malignancy

53
Q

What is necrotising sialometaplasia?

A

Benign inflammatory disease

54
Q

What histology of necrotising sialometaplasia?

A

Squamous metaplasia of salivary ducts - islands of epithelium deep connective tissue
Necrosis of acini