Non-narcotic Analgesics

Question 1

NSAIDs three properties

Answer 1

analgesic
antipyretic
anti-inflammatory (except Tylenol)

Question 2

NSAIDs mechanism of action

Answer 2

inhibition of COX and the synthesis of prostaglandins

Question 3

COX-1

Answer 3

platelet aggregation
hemostasis
gastric mucosal production

Question 4

COX-2

Answer 4

pain
inflammation
fever

Question 5

NSAIDs affect on bone healing

Answer 5

decrease

Question 6

sulfonamide allergy - NSAIDs

Answer 6

selective cox-2 inhibitors are contraindicated

Question 7

impaired renal function - NSAIDs to avoid

Answer 7

toradol

Question 8

toradol dosing

Answer 8

adults >65 = 15 mg IV
adults <65 = 30 mg IV
pediatrics = 0.5 mg/kg IV, up to 15 mg

for IM double the dose

Question 9

all NSAIDs are associated with a ________ risk of acute MI

Answer 9

increased

Question 10

Tylenol overdose

Answer 10

acteylcysteine, lessens hepatic injury

Question 11

Narcan - dose, onset, half-life

Answer 11

0.4-2 mg

IV: 1-2 min
IM: 2-5 min
nasal: 8-13 min

may be shorter than opioid, need to evaluate for redosing