Non Melanoma Skin Cancer Flashcards
0
Q
7 risk factors?
A
Uv exposure Fair skin Increasing age Immunosuppression Genetic (Gorlin's syndrome/xeroderma pigmentosum) Sites of chronic inflammation HPV
1
Q
2 precursors to scc
A
Actinic keratosis
Intraepidermal carcinoma
2
Q
Broad features of BCC
A
80% Slow growing Usually asymp Low metastatic potential Only locally invasive
3
Q
Types of BCC
A
Nodular
Superficial
Morpheic
Pigmented
4
Q
What factors confer increased risk of recurrence of bcc?
A
Increased tumour size Tumour site Poorly defined margins Morpheic subtype Histological aggression Previous treatment failure
5
Q
Broad features of SCC
A
20%
Can metastasise
5 year 75-90%
Grows over WEEKS
6
Q
8 factors increasing likelihood of mets
A
Site- ear/lip Size > 2cm Thicker depth Non sun exposed site Poorly differentiated Immunosuppressed Mucosal SCC Peri neural invasion
7
Q
3 treatment options for SCC
A
Simple excision
Radiotherapy
Mohs micrographic surgery
8
Q
What is actinic keratosis?
A
Very common Dysplastic lesion Pre cancer Hyperkeratotic 2% progress to cancer
9
Q
Treatment of AK?
A
Cryo Efudix cream C&C PDT DICLOFENAC gel Imiquoumous
10
Q
Types of intradermal carcinoma?
A
Bowers disease
Intraepithelial carcinoma
Squamous cell carcinoma
11
Q
Treatment for Intradermal carcinoma
A
Cryo Efudix C&C Excision PDT Imiquimod
12
Q
What forms when keratin compacts?
A
Cutaneous horn
13
Q
What may a cutaneous horn at its base?
A
AK, IEC, SCC