Non-fermenting Gm (-) bacteria Flashcards

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1
Q

Do Non-fermenting Gram-negative bacteria (NFGNB) ferment sugars?

A

no

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2
Q

What are the Non-fermenting Gram-negative bacteria (NFGNB) (hospital acquired Gm-)?

A
  • Pseudomonas
  • Stenotrophomas
  • Acinetobacter
  • Burkholderia
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3
Q

Where do NFGNB live?

A
  • not in the GI tract
  • live in islands everywhere
  • cause lots of nosocomial infections
  • not typically found in nutrient rich areas
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4
Q

Which of the following persons is at highest risk for infection due to a non-fermenting Gram-negative bacillus?

A. 19 year-old college student with meningitis

B. 25 year-old man with a sexually transmitted disease

C. 75 year-old man with nosocomial pneumonia after admission for a stroke

D. 10 year-old boy with an ear infection

E. 57 year-old man with bronchitis

A

C. 75 year-old man with nosocomial pneumonia after admission for a stroke

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5
Q

Why Do You Need To Suspect Pseudomonas?

A
  • labs take 48 hours
  • If you are dealing with a Pseudomonas infection but do not institute effective treatment, the chance of your patient surviving go way down
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6
Q

Which of the following persons is at highest risk for infection due to Pseudomonas?

A. 30 year-old football player with a boil

B. 80 year-old women with community-acquired pneumonia

C. 3 year-old boy with septic arthritis

D. 23 year-old man with leukemia and neutropenic fever

E. 65 year-old diabetic with otitis media

A

D. 23 year-old man with leukemia and neutropenic fever

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7
Q

What are the risk factors for stenotrophomonas infection?

A
  • In light of low pathogenicity host factors are paramount in SM infection
  • Broad-spectrum antimicrobial use especially carbapenems will select for SM colonization -Malignancy (not only neutropenia)
  • Catheters
  • Prolonged ICU stay
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8
Q

Which of the following persons is at highest risk for infection due to Stenotrophomonas?

A. 53 year-old neutropenic women status-post a stem-cell transplantation recently treated for pneumonia with a broad spectrum antibiotic

B. 27 year-old man with AIDS and meningitis

C. 37 year old alcoholic with pancreatitis and subsequent pancreatic abscess

D. 23 year-old women with cystitis

A

A. 53 year-old neutropenic women status-post a stem-cell transplantation recently treated for pneumonia with a broad spectrum antibiotic

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9
Q

Which of the following persons is at highest risk for infection due to Acinetobacter?

A. 57 year-old man with community-acquired pneumonia

B. 27 year-old man with AIDS and meningitis

C. 43 year-old man with catheter-related bacteremia after 2 week stay in an intensive care unit

D. 80 year-old nursing home resident with post-influenza pneumonia

A

C. 43 year-old man with catheter-related bacteremia after 2 week stay in an intensive care unit

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10
Q

What is Cepacia syndrome and what causes it?

A
  • Necrotizing granulomatous pneumonia with bacteremia & death
  • caused by Burkholderia
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11
Q

You are on your pediatric ward month and a 18 month old boy is admitted for fever. Blood cultures grow Burkholderia cepacia. What do you need to do?

A

Do a workup for chronic granulomatous disease

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12
Q

What risk factors increase risk for Burkholderia cepacia infection?

A
  • Cystic fibrosis
  • Chronic granulomatous disease
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13
Q

Which of the following persons is NOT at significant risk for infection due to Burkholderia cepacia complex?

A. 19 year-old women with cystic fibrosis and pneumonia

B. 11 year-old boy with chronic granulomatous disease and pneumonia

C. 37 year-old man with leukemia, neutropenia, and a bloodstream catheter infection

D. 19 year-old women with cystic fibrosis and a urinary tract infection

A

D. 19 year-old women with cystic fibrosis and a urinary tract infection

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14
Q

What organism grows a blue-green colony on blood agar?

A

-Pseudomonas aeruginosa

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15
Q

What infections are caused by Pseudomonas?

A
  1. Burns
  2. Endocarditis
  3. Pneumonia
  4. Sepsis
  5. External malignant otitis media
  6. UTI
  7. Diabetic Osteomyelitis

(BE PSEUDO)

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16
Q

What organism do you suspect in nosocomial infections in chronic granulomatous and cystic fibrosis patients?

A

Burkholderia

17
Q

What are the four W’s of hospital aquired gram negative bacteria (NFGNB)?

A

Wind (pneumonia)

Water (UTI)

Wound

Wires (IV lines)

18
Q

What organism causes infections that smells like grapes?

A

Pseudomonas

19
Q

What bug are we considering in children who develop osteomyelitis secondary to a puncture wound to the foot, usually a nail through a sweaty tennis shoe?

A

Pseudomonas

20
Q

What two bugs are frequent causes of right heart valve endocarditis in IV drug users?

A

S. aureus

Pseudomonas

21
Q

What antibiotic does Stenotrophomonas love?

A

Carbapenems