Non-epithelial Ovarian Cancer

Question 1

Large, round, ovoid or
polygonal cells
 With abundant, clear, very pale
staining cytoplasm  Large and irregular nuclei w/
prominent nucleoli  Mitotic figure seen

Answer 1

DYSGERMINOMA

Question 2

Immature tissues from all 3
germ cell layers
 Immature neural elements
are common and may
correlate with outcome

Answer 2

IMMATURE TERATOMA

Question 3

Presence of endodermal sinus or
SCHILLER DUVAL BODIES  Cystic spaces lined w/ a layer of
flattened or irregular endothelium into w/c projects glomerulus tuft with central vascular core
 Contains clear, glassy cytoplasm

Answer 3

ENDODERMAL SINUS TUMOR

Question 4

large predominantly cystic mass measuring 20 to 30
cms in greatest diameter o Large, solid, soft tissue components with low level
echoes intermixed with numerous septations

Answer 4

ENDODERMAL SINUS TUMOR

Question 5

Smooth, lobulated surface  Granular and frequently trabeculated
 Yellow or gray-yellow

Answer 5

GRANULOSA STROMAL CELL TUMORS

Question 6

Tumor marker: inhibin

Answer 6

GRANULOSA STROMAL CELL TUMORS